CSTF1 (cleavage stimulation factor subunit 1)

2003-02-01  

Identity

HGNC
LOCATION
20q13.2
LOCUSID
ALIAS
CstF-50,CstFp50
FUSION GENES

Other Information

Locus ID:

NCBI: 1477
MIM: 600369
HGNC: 2483
Ensembl: ENSG00000101138

Variants:

dbSNP: 1477
ClinVar: 1477
TCGA: ENSG00000101138
COSMIC: CSTF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101138ENST00000217109Q05048
ENSG00000101138ENST00000415828A0A0A0MSZ9
ENSG00000101138ENST00000428552A3KFI9
ENSG00000101138ENST00000452950A0A0A0MSZ9
ENSG00000101138ENST00000490539A0A087WV92
ENSG00000101138ENST00000493039A0A087WV92

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
mRNA surveillance pathwayKEGGko03015
mRNA surveillance pathwayKEGGhsa03015
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Transcription TerminationREACTOMER-HSA-73856
Cleavage of Growing Transcript in the Termination RegionREACTOMER-HSA-109688
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
mRNA 3'-end processingREACTOMER-HSA-72187
Processing of Capped Intronless Pre-mRNAREACTOMER-HSA-75067
Processing of Intronless Pre-mRNAsREACTOMER-HSA-77595

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.32
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.25
191245062009Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.22
188420002008The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50.15
196251762009PTEN identified as important risk factor of chronic obstructive pulmonary disease.12
158782322006A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats.6
191701962009Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.5

Citation

Dessen P

CSTF1 (cleavage stimulation factor subunit 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40182/cstf1