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CSTF2 (cleavage stimulation factor subunit 2)

Identity

Alias_namescleavage stimulation factor, 3' pre-RNA, subunit 2, 64kD
cleavage stimulation factor, 3' pre-RNA, subunit 2
Alias_symbol (synonym)CstF-64
Other alias
HGNC (Hugo) CSTF2
LocusID (NCBI) 1478
Atlas_Id 52575
Location Xq22.1  [Link to chromosome band Xq22]
Location_base_pair Starts at 100820363 and ends at 100841520 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CSTF2 (Xq22.1) / CSTF2 (Xq22.1)NDRG1 (8q24.22) / CSTF2 (Xq22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CSTF2   2484
Cards
Entrez_Gene (NCBI)CSTF2  1478  cleavage stimulation factor subunit 2
AliasesCstF-64
GeneCards (Weizmann)CSTF2
Ensembl hg19 (Hinxton)ENSG00000101811 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101811 [Gene_View]  chrX:100820363-100841520 [Contig_View]  CSTF2 [Vega]
ICGC DataPortalENSG00000101811
TCGA cBioPortalCSTF2
AceView (NCBI)CSTF2
Genatlas (Paris)CSTF2
WikiGenes1478
SOURCE (Princeton)CSTF2
Genetics Home Reference (NIH)CSTF2
Genomic and cartography
GoldenPath hg38 (UCSC)CSTF2  -     chrX:100820363-100841520 +  Xq22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CSTF2  -     Xq22.1   [Description]    (hg19-Feb_2009)
EnsemblCSTF2 - Xq22.1 [CytoView hg19]  CSTF2 - Xq22.1 [CytoView hg38]
Mapping of homologs : NCBICSTF2 [Mapview hg19]  CSTF2 [Mapview hg38]
OMIM300907   
Gene and transcription
Genbank (Entrez)AI826277 AK095684 AK300600 AW016125 BC017712
RefSeq transcript (Entrez)NM_001306206 NM_001306209 NM_001325
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CSTF2
Cluster EST : UnigeneHs.132370 [ NCBI ]
CGAP (NCI)Hs.132370
Alternative Splicing GalleryENSG00000101811
Gene ExpressionCSTF2 [ NCBI-GEO ]   CSTF2 [ EBI - ARRAY_EXPRESS ]   CSTF2 [ SEEK ]   CSTF2 [ MEM ]
Gene Expression Viewer (FireBrowse)CSTF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1478
GTEX Portal (Tissue expression)CSTF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP33240   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP33240  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP33240
Splice isoforms : SwissVarP33240
PhosPhoSitePlusP33240
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)CSTF2    CSTF2_hinge    CSTF_C    Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)CSTF2_hinge (PF14327)    CSTF_C (PF14304)    RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam14327    pfam14304    pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)CSTF2
DMDM Disease mutations1478
Blocks (Seattle)CSTF2
PDB (SRS)1P1T    2J8P   
PDB (PDBSum)1P1T    2J8P   
PDB (IMB)1P1T    2J8P   
PDB (RSDB)1P1T    2J8P   
Structural Biology KnowledgeBase1P1T    2J8P   
SCOP (Structural Classification of Proteins)1P1T    2J8P   
CATH (Classification of proteins structures)1P1T    2J8P   
SuperfamilyP33240
Human Protein AtlasENSG00000101811
Peptide AtlasP33240
HPRD02652
IPIIPI00013256   IPI00607841   IPI00902991   IPI00909622   IPI01009007   IPI01012987   
Protein Interaction databases
DIP (DOE-UCLA)P33240
IntAct (EBI)P33240
FunCoupENSG00000101811
BioGRIDCSTF2
STRING (EMBL)CSTF2
ZODIACCSTF2
Ontologies - Pathways
QuickGOP33240
Ontology : AmiGOmRNA splicing, via spliceosome  RNA binding  mRNA binding  protein binding  nucleoplasm  nucleoplasm  mRNA cleavage and polyadenylation specificity factor complex  termination of RNA polymerase II transcription  mRNA polyadenylation  tRNA splicing, via endonucleolytic cleavage and ligation  nuclear body  mRNA 3'-end processing  cleavage body  pre-mRNA cleavage required for polyadenylation  
Ontology : EGO-EBImRNA splicing, via spliceosome  RNA binding  mRNA binding  protein binding  nucleoplasm  nucleoplasm  mRNA cleavage and polyadenylation specificity factor complex  termination of RNA polymerase II transcription  mRNA polyadenylation  tRNA splicing, via endonucleolytic cleavage and ligation  nuclear body  mRNA 3'-end processing  cleavage body  pre-mRNA cleavage required for polyadenylation  
Pathways : BIOCARTAPolyadenylation of mRNA [Genes]   
Pathways : KEGGmRNA surveillance pathway   
NDEx NetworkCSTF2
Atlas of Cancer Signalling NetworkCSTF2
Wikipedia pathwaysCSTF2
Orthology - Evolution
OrthoDB1478
GeneTree (enSembl)ENSG00000101811
Phylogenetic Trees/Animal Genes : TreeFamCSTF2
HOVERGENP33240
HOGENOMP33240
Homologs : HomoloGeneCSTF2
Homology/Alignments : Family Browser (UCSC)CSTF2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCSTF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CSTF2
dbVarCSTF2
ClinVarCSTF2
1000_GenomesCSTF2 
Exome Variant ServerCSTF2
ExAC (Exome Aggregation Consortium)CSTF2 (select the gene name)
Genetic variants : HAPMAP1478
Genomic Variants (DGV)CSTF2 [DGVbeta]
DECIPHERCSTF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCSTF2 
Mutations
ICGC Data PortalCSTF2 
TCGA Data PortalCSTF2 
Broad Tumor PortalCSTF2
OASIS PortalCSTF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCSTF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCSTF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch CSTF2
DgiDB (Drug Gene Interaction Database)CSTF2
DoCM (Curated mutations)CSTF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CSTF2 (select a term)
intoGenCSTF2
Cancer3DCSTF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300907   
Orphanet
MedgenCSTF2
Genetic Testing Registry CSTF2
NextProtP33240 [Medical]
TSGene1478
GENETestsCSTF2
Target ValidationCSTF2
Huge Navigator CSTF2 [HugePedia]
snp3D : Map Gene to Disease1478
BioCentury BCIQCSTF2
ClinGenCSTF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1478
Chemical/Pharm GKB GenePA26986
Clinical trialCSTF2
Miscellaneous
canSAR (ICR)CSTF2 (select the gene name)
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCSTF2
EVEXCSTF2
GoPubMedCSTF2
iHOPCSTF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:29:49 CEST 2017

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