CSTF2T (cleavage stimulation factor subunit 2 tau variant)

2007-02-01  

Identity

HGNC
LOCATION
10q21.1
LOCUSID
ALIAS
CstF-64T

Other Information

Locus ID:

NCBI: 23283
MIM: 611968
HGNC: 17086
Ensembl: ENSG00000177613

Variants:

dbSNP: 23283
ClinVar: 23283
TCGA: ENSG00000177613
COSMIC: CSTF2T

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177613ENST00000331173Q9H0L4

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
mRNA surveillance pathwayKEGGko03015
mRNA surveillance pathwayKEGGhsa03015
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Transcription TerminationREACTOMER-HSA-73856
Cleavage of Growing Transcript in the Termination RegionREACTOMER-HSA-109688
Processing of Capped Intron-Containing Pre-mRNAREACTOMER-HSA-72203
mRNA SplicingREACTOMER-HSA-72172
mRNA Splicing - Major PathwayREACTOMER-HSA-72163
mRNA 3'-end processingREACTOMER-HSA-72187
Processing of Capped Intronless Pre-mRNAREACTOMER-HSA-75067
Processing of Intronless Pre-mRNAsREACTOMER-HSA-77595

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
127733962003Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein.73
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
197795652009Enterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylation.66
157674282005A 57-nucleotide upstream early polyadenylation element in human papillomavirus type 16 interacts with hFip1, CstF-64, hnRNP C1/C2, and polypyrimidine tract binding protein.34
241498452013Overlapping and distinct functions of CstF64 and CstF64τ in mammalian mRNA 3' processing.34
124089682002The gene CSTF2T, encoding the human variant CstF-64 polyadenylation protein tauCstF-64, lacks introns and may be associated with male sterility.14
283349772017sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs.13

Citation

Dessen P

CSTF2T (cleavage stimulation factor subunit 2 tau variant)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46387/cstf2t