CTDSPL2 (CTD small phosphatase like 2)

2014-11-01  

Identity

HGNC
LOCATION
15q15.3
LOCUSID
ALIAS
HSPC058,HSPC129,SCP4
FUSION GENES

Other Information

Locus ID:

NCBI: 51496
MIM: 618739
HGNC: 26936
Ensembl: ENSG00000137770

Variants:

dbSNP: 51496
ClinVar: 51496
TCGA: ENSG00000137770
COSMIC: CTDSPL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137770ENST00000260327Q05D32
ENSG00000137770ENST00000260327A0A024R5Q8
ENSG00000137770ENST00000558373Q05D32
ENSG00000137770ENST00000558791H0YMH7
ENSG00000137770ENST00000558966Q05D32
ENSG00000137770ENST00000558966A0A024R5Q8
ENSG00000137770ENST00000558968H0YNU2
ENSG00000137770ENST00000559793H0YNW9
ENSG00000137770ENST00000560620H0YMB4

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
209323292010CTD small phosphatase like 2 (CTDSPL2) can increase ε- and γ-globin gene expression in K562 cells and CD34+ cells derived from umbilical cord blood.5
269200472016Human SCP4 is a chromatin-associated CTD phosphatase and exhibits the dynamic translocation during erythroid differentiation.4
285067622017The nuclear phosphatase SCP4 regulates FoxO transcription factors during muscle wasting in chronic kidney disease.4
266743422016A systematic study of nuclear interactome of C-terminal domain small phosphatase-like 2 using inducible expression system and shotgun proteomics.3
296185182018C-terminal domain small phosphatase-like 2 promotes epithelial-to-mesenchymal transition via Snail dephosphorylation and stabilization.1

Citation

Dessen P

CTDSPL2 (CTD small phosphatase like 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62181/ctdspl2