Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1495
MIM: 116805
HGNC: 2509
Ensembl: ENSG00000044115
Variants:
dbSNP: 1495
ClinVar: 1495
TCGA: ENSG00000044115
COSMIC: CTNNA1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36928388 | 2023 | Distinct inter-domain interactions of dimeric versus monomeric α-catenin link cell junctions to filaments. | 3 |
| 36928388 | 2023 | Distinct inter-domain interactions of dimeric versus monomeric α-catenin link cell junctions to filaments. | 3 |
| 35988963 | 2022 | Familial and hereditary gastric cancer, an overview. | 9 |
| 36038258 | 2022 | First estimates of diffuse gastric cancer risks for carriers of CTNNA1 germline pathogenic variants. | 7 |
| 35988963 | 2022 | Familial and hereditary gastric cancer, an overview. | 9 |
| 36038258 | 2022 | First estimates of diffuse gastric cancer risks for carriers of CTNNA1 germline pathogenic variants. | 7 |
| 33137351 | 2021 | Clinical and Genetic Findings in CTNNA1-Associated Macular Pattern Dystrophy. | 6 |
| 33378218 | 2021 | Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling. | 6 |
| 33497368 | 2021 | Catenin α 1 mutations cause familial exudative vitreoretinopathy by overactivating Norrin/β-catenin signaling. | 26 |
| 34425242 | 2021 | Cancer predisposition and germline CTNNA1 variants. | 14 |
| 33137351 | 2021 | Clinical and Genetic Findings in CTNNA1-Associated Macular Pattern Dystrophy. | 6 |
| 33378218 | 2021 | Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling. | 6 |
| 33497368 | 2021 | Catenin α 1 mutations cause familial exudative vitreoretinopathy by overactivating Norrin/β-catenin signaling. | 26 |
| 34425242 | 2021 | Cancer predisposition and germline CTNNA1 variants. | 14 |
| 32051609 | 2020 | Loss-of-function variants in CTNNA1 detected on multigene panel testing in individuals with gastric or breast cancer. | 21 |
Citation
Dessen P
CTNNA1 (catenin alpha 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/366/ctnna1
