Identity
HGNC
LOCATION
10q21.3
LOCUSID
ALIAS
ARVD13,VR22
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29119
MIM: 607667
HGNC: 2511
Ensembl: ENSG00000183230
Variants:
dbSNP: 29119
ClinVar: 29119
TCGA: ENSG00000183230
COSMIC: CTNNA3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183230 | ENST00000330298 | Q5SW23 |
| ENSG00000183230 | ENST00000433211 | Q9UI47 |
| ENSG00000183230 | ENST00000494580 | V9GYW4 |
| ENSG00000183230 | ENST00000545309 | F2Z2R0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation | associated | PD | ||
| PA452229 | antidepressants | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37126683 | 2023 | Proteomics and phosphoproteomics of failing human left ventricle identifies dilated cardiomyopathy-associated phosphorylation of CTNNA3. | 4 |
| 37126683 | 2023 | Proteomics and phosphoproteomics of failing human left ventricle identifies dilated cardiomyopathy-associated phosphorylation of CTNNA3. | 4 |
| 34717601 | 2021 | CTNNA3 genetic polymorphism may be a new genetic signal of type 2 diabetes in the Chinese Han population: a case control study. | 1 |
| 34717601 | 2021 | CTNNA3 genetic polymorphism may be a new genetic signal of type 2 diabetes in the Chinese Han population: a case control study. | 1 |
| 28699631 | 2017 | Co-inheritance of mutations associated with arrhythmogenic cardiomyopathy and hypertrophic cardiomyopathy. | 9 |
| 28801652 | 2017 | Assessment of Three New Loci from Genome-wide Association Study in Essential Tremor in Chinese population. | 5 |
| 28699631 | 2017 | Co-inheritance of mutations associated with arrhythmogenic cardiomyopathy and hypertrophic cardiomyopathy. | 9 |
| 28801652 | 2017 | Assessment of Three New Loci from Genome-wide Association Study in Essential Tremor in Chinese population. | 5 |
| 26882563 | 2016 | CTNNA3 is a tumor suppressor in hepatocellular carcinomas and is inhibited by miR-425. | 24 |
| 27091189 | 2016 | Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway. | 11 |
| 27272392 | 2016 | Polymorphisms of CHAT but not TFAM or VR22 are Associated with Alzheimer Disease Risk. | 2 |
| 27765635 | 2016 | Molecular Analysis of Hybrid Neurofibroma/Schwannoma Identifies Common Monosomy 22 and α-T-Catenin/CTNNA3 as a Novel Candidate Tumor Suppressor. | 11 |
| 27797806 | 2016 | Genome-wide association study in essential tremor identifies three new loci. | 35 |
| 26882563 | 2016 | CTNNA3 is a tumor suppressor in hepatocellular carcinomas and is inhibited by miR-425. | 24 |
| 27091189 | 2016 | Genome-wide association study of antidepressant response: involvement of the inorganic cation transmembrane transporter activity pathway. | 11 |
Citation
Dessen P
CTNNA3 (catenin alpha 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-06-01
Online version: http://atlasgeneticsoncology.org/gene/47565/ctnna3
