| beta-catenin is a target for the ubiquitin-proteasome pathway. |
| Aberle H, Bauer A, Stappert J, Kispert A, Kemler R |
| The EMBO journal. 1997 ; 16 (13) : 3797-3804. |
| PMID 9233789 |
| |
| Yeast artificial chromosome cloning of the beta-catenin locus on human chromosome 3p21-22. |
| Bailey A, Norris AL, Leek JP, Clissold PM, Carr IM, Ogilvie DJ, Morrison JF, Meredith DM, Markham AF |
| Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology. 1995 ; 3 (3) : 201-203. |
| PMID 7780664 |
| |
| Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. |
| Behrens J, Jerchow BA, Würtele M, Grimm J, Asbrand C, Wirtz R, Kühl M, Wedlich D, Birchmeier W |
| Science (New York, N.Y.). 1998 ; 280 (5363) : 596-599. |
| PMID 9554852 |
| |
| Functional interaction of beta-catenin with the transcription factor LEF-1. |
| Behrens J, von Kries JP, Kühl M, Bruhn L, Wedlich D, Grosschedl R, Birchmeier W |
| Nature. 1996 ; 382 (6592) : 638-642. |
| PMID 8757136 |
| |
| Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma. |
| Bläker H, Hofmann WJ, Rieker RJ, Penzel R, Graf M, Otto HF |
| Genes, chromosomes & cancer. 1999 ; 25 (4) : 399-402. |
| PMID 10398436 |
| |
| A common human skin tumour is caused by activating mutations in beta-catenin. |
| Chan EF, Gat U, McNiff JM, Fuchs E |
| Nature genetics. 1999 ; 21 (4) : 410-413. |
| PMID 10192393 |
| |
| The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors. |
| Crawford HC, Fingleton BM, Rudolph-Owen LA, Goss KJ, Rubinfeld B, Polakis P, Matrisian LM |
| Oncogene. 1999 ; 18 (18) : 2883-2891. |
| PMID 10362259 |
| |
| Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin. |
| Fagotto F, Glück U, Gumbiner BM |
| Current biology : CB. 1998 ; 8 (4) : 181-190. |
| PMID 9501980 |
| |
| Frequent beta-catenin aberration in human hepatocellular carcinoma. |
| Fujie H, Moriya K, Shintani Y, Tsutsumi T, Takayama T, Makuuchi M, Kimura S, Koike K |
| Hepatology research : the official journal of the Japan Society of Hepatology. 2001 ; 20 (1) : 39-51. |
| PMID 11282485 |
| |
| Signal transduction of beta-catenin. |
| Gumbiner BM |
| Current opinion in cell biology. 1995 ; 7 (5) : 634-640. |
| PMID 8573337 |
| |
| Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. |
| Harada N, Tamai Y, Ishikawa T, Sauer B, Takaku K, Oshima M, Taketo MM |
| The EMBO journal. 1999 ; 18 (21) : 5931-5942. |
| PMID 10545105 |
| |
| Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. |
| Hart MJ, de los Santos R, Albert IN, Rubinfeld B, Polakis P |
| Current biology : CB. 1998 ; 8 (10) : 573-581. |
| PMID 9601641 |
| |
| APC mutations in sporadic medulloblastomas. |
| Huang H, Mahler-Araujo BM, Sankila A, Chimelli L, Yonekawa Y, Kleihues P, Ohgaki H |
| The American journal of pathology. 2000 ; 156 (2) : 433-437. |
| PMID 10666372 |
| |
| Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. |
| Huber O, Korn R, McLaughlin J, Ohsugi M, Herrmann BG, Kemler R |
| Mechanisms of development. 1996 ; 59 (1) : 3-10. |
| PMID 8892228 |
| |
| Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. |
| Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, Kikuchi A |
| The EMBO journal. 1998 ; 17 (5) : 1371-1384. |
| PMID 9482734 |
| |
| Beta-catenin mutations in cell lines established from human colorectal cancers. |
| Ilyas M, Tomlinson IP, Rowan A, Pignatelli M, Bodmer WF |
| Proceedings of the National Academy of Sciences of the United States of America. 1997 ; 94 (19) : 10330-10334. |
| PMID 9294210 |
| |
| Activation of the beta-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations. |
| Iwao K, Nakamori S, Kameyama M, Imaoka S, Kinoshita M, Fukui T, Ishiguro S, Nakamura Y, Miyoshi Y |
| Cancer research. 1998 ; 58 (5) : 1021-1026. |
| PMID 9500465 |
| |
| Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. |
| Koch A, Denkhaus D, Albrecht S, Leuschner I, von Schweinitz D, Pietsch T |
| Cancer research. 1999 ; 59 (2) : 269-273. |
| PMID 9927029 |
| |
| Gastrin is a target of the beta-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis. |
| Koh TJ, Bulitta CJ, Fleming JV, Dockray GJ, Varro A, Wang TC |
| The Journal of clinical investigation. 2000 ; 106 (4) : 533-539. |
| PMID 10953028 |
| |
| Localization of the human beta-catenin gene (CTNNB1) to 3p21: a region implicated in tumor development. |
| Kraus C, Liehr T, Hülsken J, Behrens J, Birchmeier W, Grzeschik KH, Ballhausen WG |
| Genomics. 1994 ; 23 (1) : 272-274. |
| PMID 7829088 |
| |
| Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity. |
| Legoix P, Bluteau O, Bayer J, Perret C, Balabaud C, Belghiti J, Franco D, Thomas G, Laurent-Puig P, Zucman-Rossi J |
| Oncogene. 1999 ; 18 (27) : 4044-4046. |
| PMID 10435629 |
| |
| Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling. |
| Liu W, Dong X, Mai M, Seelan RS, Taniguchi K, Krishnadath KK, Halling KC, Cunningham JM, Boardman LA, Qian C, Christensen E, Schmidt SS, Roche PC, Smith DI, Thibodeau SN |
| Nature genetics. 2000 ; 26 (2) : 146-147. |
| PMID 11017067 |
| |
| The transcriptional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobin. |
| Miravet S, Piedra J, Miró F, Itarte E, García de Herreros A, Duñach M |
| The Journal of biological chemistry. 2002 ; 277 (3) : 1884-1891. |
| PMID 11711551 |
| |
| Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. |
| Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW |
| Science (New York, N.Y.). 1997 ; 275 (5307) : 1787-1790. |
| PMID 9065402 |
| |
| Genomic organization of the human beta-catenin gene (CTNNB1). |
| Nollet F, Berx G, Molemans F, van Roy F |
| Genomics. 1996 ; 32 (3) : 413-424. |
| PMID 8838805 |
| |
| Oncogenic beta-catenin and MMP-7 (matrilysin) cosegregate in late-stage clinical colon cancer. |
| Ougolkov AV, Yamashita K, Mai M, Minamoto T |
| Gastroenterology. 2002 ; 122 (1) : 60-71. |
| PMID 11781281 |
| |
| Stabilization of beta-catenin by genetic defects in melanoma cell lines. |
| Rubinfeld B, Robbins P, El-Gamil M, Albert I, Porfiri E, Polakis P |
| Science (New York, N.Y.). 1997 ; 275 (5307) : 1790-1792. |
| PMID 9065403 |
| |
| Mutational analysis of beta-catenin gene in Japanese ovarian carcinomas: frequent mutations in endometrioid carcinomas. |
| Sagae S, Kobayashi K, Nishioka Y, Sugimura M, Ishioka S, Nagata M, Terasawa K, Tokino T, Kudo R |
| Japanese journal of cancer research : Gann. 1999 ; 90 (5) : 510-515. |
| PMID 10391090 |
| |
| Possible association between higher beta-catenin mRNA expression and mutated beta-catenin in sporadic desmoid tumors: real-time semiquantitative assay by TaqMan polymerase chain reaction. |
| Saito T, Oda Y, Kawaguchi K, Tanaka K, Matsuda S, Tamiya S, Iwamoto Y, Tsuneyoshi M |
| Laboratory investigation; a journal of technical methods and pathology. 2002 ; 82 (1) : 97-103. |
| PMID 11796830 |
| |
| The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. |
| Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R, Ben-Ze'ev A |
| Proceedings of the National Academy of Sciences of the United States of America. 1999 ; 96 (10) : 5522-5527. |
| PMID 10318916 |
| |
| Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer. |
| Sparks AB, Morin PJ, Vogelstein B, Kinzler KW |
| Cancer research. 1998 ; 58 (6) : 1130-1134. |
| PMID 9515795 |
| |
| Association of the APC tumor suppressor protein with catenins. |
| Su LK, Vogelstein B, Kinzler KW |
| Science (New York, N.Y.). 1993 ; 262 (5140) : 1734-1737. |
| PMID 8259519 |
| |
| Frizzled-10, up-regulated in primary colorectal cancer, is a positive regulator of the WNT - beta-catenin - TCF signaling pathway. |
| Terasaki H, Saitoh T, Shiokawa K, Katoh M |
| International journal of molecular medicine. 2002 ; 9 (2) : 107-112. |
| PMID 11786918 |
| |
| The gene for the APC-binding protein beta-catenin (CTNNB1) maps to chromosome 3p22, a region frequently altered in human malignancies. |
| Trent JM, Wiltshire R, Su LK, Nicolaides NC, Vogelstein B, Kinzler KW |
| Cytogenetics and cell genetics. 1995 ; 71 (4) : 343-344. |
| PMID 8521721 |
| |
| Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas. |
| de La Coste A, Romagnolo B, Billuart P, Renard CA, Buendia MA, Soubrane O, Fabre M, Chelly J, Beldjord C, Kahn A, Perret C |
| Proceedings of the National Academy of Sciences of the United States of America. 1998 ; 95 (15) : 8847-8851. |
| PMID 9671767 |
| |
| Assignment of the human beta-catenin gene (CTNNB1) to 3p22-->p21.3 by fluorescence in situ hybridization. |
| van Hengel J, Nollet F, Berx G, van Roy N, Speleman F, van Roy F |
| Cytogenetics and cell genetics. 1995 ; 70 (1-2) : 68-70. |
| PMID 7736793 |
| |
