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CTPS1 (CTP synthase 1)

Identity

Alias_namesCTPS
CTP synthase
Other aliasIMD24
HGNC (Hugo) CTPS1
LocusID (NCBI) 1503
Atlas_Id 40199
Location 1p34.2  [Link to chromosome band 1p34]
Location_base_pair Starts at 41454120 and ends at 41478237 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CTPS1   2519
Cards
Entrez_Gene (NCBI)CTPS1  1503  CTP synthase 1
AliasesCTPS; IMD24
GeneCards (Weizmann)CTPS1
Ensembl hg19 (Hinxton)ENSG00000171793 [Gene_View]  chr1:41454120-41478237 [Contig_View]  CTPS1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000171793 [Gene_View]  chr1:41454120-41478237 [Contig_View]  CTPS1 [Vega]
ICGC DataPortalENSG00000171793
TCGA cBioPortalCTPS1
AceView (NCBI)CTPS1
Genatlas (Paris)CTPS1
WikiGenes1503
SOURCE (Princeton)CTPS1
Genetics Home Reference (NIH)CTPS1
Genomic and cartography
GoldenPath hg19 (UCSC)CTPS1  -     chr1:41454120-41478237 +  1p34.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CTPS1  -     1p34.2   [Description]    (hg38-Dec_2013)
EnsemblCTPS1 - 1p34.2 [CytoView hg19]  CTPS1 - 1p34.2 [CytoView hg38]
Mapping of homologs : NCBICTPS1 [Mapview hg19]  CTPS1 [Mapview hg38]
OMIM123860   615897   
Gene and transcription
Genbank (Entrez)AI190299 AK130549 AK225899 AK297386 AK299122
RefSeq transcript (Entrez)NM_001301237 NM_001905
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_034208 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)CTPS1
Cluster EST : UnigeneHs.473087 [ NCBI ]
CGAP (NCI)Hs.473087
Alternative Splicing GalleryENSG00000171793
Gene ExpressionCTPS1 [ NCBI-GEO ]   CTPS1 [ EBI - ARRAY_EXPRESS ]   CTPS1 [ SEEK ]   CTPS1 [ MEM ]
Gene Expression Viewer (FireBrowse)CTPS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1503
GTEX Portal (Tissue expression)CTPS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17812   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17812  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17812
Splice isoforms : SwissVarP17812
PhosPhoSitePlusP17812
Domaine pattern : Prosite (Expaxy)GATASE_TYPE_1 (PS51273)   
Domains : Interpro (EBI)Class_I_gatase-like    CTP_synthase    CTP_synthase_N    GATASE    P-loop_NTPase   
Domain families : Pfam (Sanger)CTP_synth_N (PF06418)    GATase (PF00117)   
Domain families : Pfam (NCBI)pfam06418    pfam00117   
Conserved Domain (NCBI)CTPS1
DMDM Disease mutations1503
Blocks (Seattle)CTPS1
PDB (SRS)2VO1   
PDB (PDBSum)2VO1   
PDB (IMB)2VO1   
PDB (RSDB)2VO1   
Structural Biology KnowledgeBase2VO1   
SCOP (Structural Classification of Proteins)2VO1   
CATH (Classification of proteins structures)2VO1   
SuperfamilyP17812
Human Protein AtlasENSG00000171793
Peptide AtlasP17812
HPRD00465
IPIIPI00290142   IPI01013474   IPI00921944   
Protein Interaction databases
DIP (DOE-UCLA)P17812
IntAct (EBI)P17812
FunCoupENSG00000171793
BioGRIDCTPS1
STRING (EMBL)CTPS1
ZODIACCTPS1
Ontologies - Pathways
QuickGOP17812
Ontology : AmiGOCTP synthase activity  CTP synthase activity  CTP synthase activity  CTP synthase activity  ATP binding  cytosol  nucleobase-containing compound metabolic process  CTP biosynthetic process  CTP biosynthetic process  glutamine metabolic process  nucleobase-containing small molecule interconversion  membrane  T cell proliferation  B cell proliferation  response to drug  'de novo' CTP biosynthetic process  
Ontology : EGO-EBICTP synthase activity  CTP synthase activity  CTP synthase activity  CTP synthase activity  ATP binding  cytosol  nucleobase-containing compound metabolic process  CTP biosynthetic process  CTP biosynthetic process  glutamine metabolic process  nucleobase-containing small molecule interconversion  membrane  T cell proliferation  B cell proliferation  response to drug  'de novo' CTP biosynthetic process  
Pathways : KEGGPyrimidine metabolism   
NDEx NetworkCTPS1
Atlas of Cancer Signalling NetworkCTPS1
Wikipedia pathwaysCTPS1
Orthology - Evolution
OrthoDB1503
GeneTree (enSembl)ENSG00000171793
Phylogenetic Trees/Animal Genes : TreeFamCTPS1
HOVERGENP17812
HOGENOMP17812
Homologs : HomoloGeneCTPS1
Homology/Alignments : Family Browser (UCSC)CTPS1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCTPS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CTPS1
dbVarCTPS1
ClinVarCTPS1
1000_GenomesCTPS1 
Exome Variant ServerCTPS1
ExAC (Exome Aggregation Consortium)CTPS1 (select the gene name)
Genetic variants : HAPMAP1503
Genomic Variants (DGV)CTPS1 [DGVbeta]
DECIPHER (Syndromes)1:41454120-41478237  ENSG00000171793
CONAN: Copy Number AnalysisCTPS1 
Mutations
ICGC Data PortalCTPS1 
TCGA Data PortalCTPS1 
Broad Tumor PortalCTPS1
OASIS PortalCTPS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCTPS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCTPS1
BioMutasearch CTPS1
DgiDB (Drug Gene Interaction Database)CTPS1
DoCM (Curated mutations)CTPS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CTPS1 (select a term)
intoGenCTPS1
Cancer3DCTPS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM123860    615897   
Orphanet23115   
MedgenCTPS1
Genetic Testing Registry CTPS1
NextProtP17812 [Medical]
TSGene1503
GENETestsCTPS1
Huge Navigator CTPS1 [HugePedia]
snp3D : Map Gene to Disease1503
BioCentury BCIQCTPS1
ClinGenCTPS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1503
Chemical/Pharm GKB GenePA27020
Clinical trialCTPS1
Miscellaneous
canSAR (ICR)CTPS1 (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCTPS1
EVEXCTPS1
GoPubMedCTPS1
iHOPCTPS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:57:59 CEST 2017

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