Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CTR9 (CTR9 homolog, Paf1/RNA polymerase II complex component)

Identity

Alias (NCBI)SH2BP1
TSBP
p150
p150TSP
HGNC (Hugo) CTR9
HGNC Alias symbKIAA0155
TSBP
p150TSP
HGNC Previous nameSH2BP1
HGNC Previous nameSH2 domain binding protein 1 (tetratricopeptide repeat containing)
 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LocusID (NCBI) 9646
Atlas_Id 55370
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 10751246 and ends at 10779746 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CTR9 (11p15.3) / ATG4C (1p31.3)CTR9 (11p15.3) / TAOK3 (12q24.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CTR9   16850
Cards
Entrez_Gene (NCBI)CTR9  9646  CTR9 homolog, Paf1/RNA polymerase II complex component
AliasesSH2BP1; TSBP; p150; p150TSP
GeneCards (Weizmann)CTR9
Ensembl hg19 (Hinxton)ENSG00000198730 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198730 [Gene_View]  ENSG00000198730 [Sequence]  chr11:10751246-10779746 [Contig_View]  CTR9 [Vega]
ICGC DataPortalENSG00000198730
TCGA cBioPortalCTR9
AceView (NCBI)CTR9
Genatlas (Paris)CTR9
WikiGenes9646
SOURCE (Princeton)CTR9
Genetics Home Reference (NIH)CTR9
Genomic and cartography
GoldenPath hg38 (UCSC)CTR9  -     chr11:10751246-10779746 +  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CTR9  -     11p15.4   [Description]    (hg19-Feb_2009)
GoldenPathCTR9 - 11p15.4 [CytoView hg19]  CTR9 - 11p15.4 [CytoView hg38]
ImmunoBaseENSG00000198730
genome Data Viewer NCBICTR9 [Mapview hg19]  
OMIM609366   
Gene and transcription
Genbank (Entrez)AK291794 BC014335 BC058914 BP223102 BP250198
RefSeq transcript (Entrez)NM_001346279 NM_014633
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CTR9
Alternative Splicing GalleryENSG00000198730
Gene ExpressionCTR9 [ NCBI-GEO ]   CTR9 [ EBI - ARRAY_EXPRESS ]   CTR9 [ SEEK ]   CTR9 [ MEM ]
Gene Expression Viewer (FireBrowse)CTR9 [ Firebrowse - Broad ]
GenevisibleExpression of CTR9 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9646
GTEX Portal (Tissue expression)CTR9
Human Protein AtlasENSG00000198730-CTR9 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PD62   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PD62  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PD62
Splice isoforms : SwissVarQ6PD62
PhosPhoSitePlusQ6PD62
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)Ctr9    TPR-contain_dom    TPR-like_helical_dom_sf    TPR_repeat   
Domain families : Pfam (Sanger)TPR_8 (PF13181)   
Domain families : Pfam (NCBI)pfam13181   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)CTR9
DMDM Disease mutations9646
Blocks (Seattle)CTR9
PDB (RSDB)5ZYQ    6GMH   
PDB Europe5ZYQ    6GMH   
PDB (PDBSum)5ZYQ    6GMH   
PDB (IMB)5ZYQ    6GMH   
Structural Biology KnowledgeBase5ZYQ    6GMH   
SCOP (Structural Classification of Proteins)5ZYQ    6GMH   
CATH (Classification of proteins structures)5ZYQ    6GMH   
SuperfamilyQ6PD62
Human Protein Atlas [tissue]ENSG00000198730-CTR9 [tissue]
Peptide AtlasQ6PD62
HPRD06717
IPIIPI00477468   IPI00975493   
Protein Interaction databases
DIP (DOE-UCLA)Q6PD62
IntAct (EBI)Q6PD62
FunCoupENSG00000198730
BioGRIDCTR9
STRING (EMBL)CTR9
ZODIACCTR9
Ontologies - Pathways
QuickGOQ6PD62
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  RNA polymerase II complex binding  endodermal cell fate commitment  inner cell mass cell differentiation  trophectodermal cell differentiation  blastocyst growth  blastocyst hatching  protein binding  nucleoplasm  nucleoplasm  regulation of transcription, DNA-templated  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  JAK-STAT cascade  histone monoubiquitination  Wnt signaling pathway  protein ubiquitination  Cdc73/Paf1 complex  Cdc73/Paf1 complex  nuclear speck  stem cell population maintenance  positive regulation of transcription elongation from RNA polymerase II promoter  histone H2B ubiquitination  transcriptionally active chromatin  SH2 domain binding  negative regulation of myeloid cell differentiation  positive regulation of transcription by RNA polymerase II  regulation of histone H3-K4 methylation  positive regulation of histone H3-K4 methylation  interleukin-6-mediated signaling pathway  cellular response to lipopolysaccharide  histone H3-K4 trimethylation  negative regulation of mRNA polyadenylation  regulation of genetic imprinting  positive regulation of histone H3-K79 methylation  positive regulation of histone H2B ubiquitination  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  RNA polymerase II complex binding  endodermal cell fate commitment  inner cell mass cell differentiation  trophectodermal cell differentiation  blastocyst growth  blastocyst hatching  protein binding  nucleoplasm  nucleoplasm  regulation of transcription, DNA-templated  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  JAK-STAT cascade  histone monoubiquitination  Wnt signaling pathway  protein ubiquitination  Cdc73/Paf1 complex  Cdc73/Paf1 complex  nuclear speck  stem cell population maintenance  positive regulation of transcription elongation from RNA polymerase II promoter  histone H2B ubiquitination  transcriptionally active chromatin  SH2 domain binding  negative regulation of myeloid cell differentiation  positive regulation of transcription by RNA polymerase II  regulation of histone H3-K4 methylation  positive regulation of histone H3-K4 methylation  interleukin-6-mediated signaling pathway  cellular response to lipopolysaccharide  histone H3-K4 trimethylation  negative regulation of mRNA polyadenylation  regulation of genetic imprinting  positive regulation of histone H3-K79 methylation  positive regulation of histone H2B ubiquitination  
NDEx NetworkCTR9
Atlas of Cancer Signalling NetworkCTR9
Wikipedia pathwaysCTR9
Orthology - Evolution
OrthoDB9646
GeneTree (enSembl)ENSG00000198730
Phylogenetic Trees/Animal Genes : TreeFamCTR9
HOGENOMQ6PD62
Homologs : HomoloGeneCTR9
Homology/Alignments : Family Browser (UCSC)CTR9
Gene fusions - Rearrangements
Fusion : QuiverCTR9
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCTR9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CTR9
dbVarCTR9
ClinVarCTR9
MonarchCTR9
1000_GenomesCTR9 
Exome Variant ServerCTR9
GNOMAD BrowserENSG00000198730
Varsome BrowserCTR9
Genetic variants : HAPMAP9646
Genomic Variants (DGV)CTR9 [DGVbeta]
DECIPHERCTR9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCTR9 
Mutations
ICGC Data PortalCTR9 
TCGA Data PortalCTR9 
Broad Tumor PortalCTR9
OASIS PortalCTR9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCTR9  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCTR9
Mutations and Diseases : HGMDCTR9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CTR9
DgiDB (Drug Gene Interaction Database)CTR9
DoCM (Curated mutations)CTR9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CTR9 (select a term)
intoGenCTR9
Cancer3DCTR9(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609366   
Orphanet
DisGeNETCTR9
MedgenCTR9
Genetic Testing Registry CTR9
NextProtQ6PD62 [Medical]
TSGene9646
GENETestsCTR9
Target ValidationCTR9
Huge Navigator CTR9 [HugePedia]
snp3D : Map Gene to Disease9646
BioCentury BCIQCTR9
ClinGenCTR9
Clinical trials, drugs, therapy
Protein Interactions : CTD9646
Pharm GKB GenePA134896774
Clinical trialCTR9
Miscellaneous
canSAR (ICR)CTR9 (select the gene name)
HarmonizomeCTR9
DataMed IndexCTR9
Probes
Litterature
PubMed75 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCTR9
EVEXCTR9
GoPubMedCTR9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 14 14:07:44 CEST 2020
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