Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CTRB1 (chymotrypsinogen B1)

Identity

Alias_namesCTRB
Other alias
HGNC (Hugo) CTRB1
LocusID (NCBI) 1504
Atlas_Id 62187
Location 16q23.1  [Link to chromosome band 16q23]
Location_base_pair Starts at 75218986 and ends at 75224927 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CTRB1   2521
Cards
Entrez_Gene (NCBI)CTRB1  1504  chymotrypsinogen B1
AliasesCTRB
GeneCards (Weizmann)CTRB1
Ensembl hg19 (Hinxton)ENSG00000168925 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168925 [Gene_View]  chr16:75218986-75224927 [Contig_View]  CTRB1 [Vega]
ICGC DataPortalENSG00000168925
TCGA cBioPortalCTRB1
AceView (NCBI)CTRB1
Genatlas (Paris)CTRB1
WikiGenes1504
SOURCE (Princeton)CTRB1
Genetics Home Reference (NIH)CTRB1
Genomic and cartography
GoldenPath hg38 (UCSC)CTRB1  -     chr16:75218986-75224927 +  16q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CTRB1  -     16q23.1   [Description]    (hg19-Feb_2009)
EnsemblCTRB1 - 16q23.1 [CytoView hg19]  CTRB1 - 16q23.1 [CytoView hg38]
Mapping of homologs : NCBICTRB1 [Mapview hg19]  CTRB1 [Mapview hg38]
OMIM118890   
Gene and transcription
Genbank (Entrez)AA844834 AW338596 BC005385 BT007356 BX497259
RefSeq transcript (Entrez)NM_001329190 NM_001906
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CTRB1
Cluster EST : UnigeneHs.610926 [ NCBI ]
CGAP (NCI)Hs.610926
Alternative Splicing GalleryENSG00000168925
Gene ExpressionCTRB1 [ NCBI-GEO ]   CTRB1 [ EBI - ARRAY_EXPRESS ]   CTRB1 [ SEEK ]   CTRB1 [ MEM ]
Gene Expression Viewer (FireBrowse)CTRB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1504
GTEX Portal (Tissue expression)CTRB1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17538   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17538  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17538
Splice isoforms : SwissVarP17538
Catalytic activity : Enzyme3.4.21.1 [ Enzyme-Expasy ]   3.4.21.13.4.21.1 [ IntEnz-EBI ]   3.4.21.1 [ BRENDA ]   3.4.21.1 [ KEGG ]   
PhosPhoSitePlusP17538
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)CTRB1
DMDM Disease mutations1504
Blocks (Seattle)CTRB1
SuperfamilyP17538
Human Protein AtlasENSG00000168925
Peptide AtlasP17538
HPRD00345
IPIIPI00015133   
Protein Interaction databases
DIP (DOE-UCLA)P17538
IntAct (EBI)P17538
FunCoupENSG00000168925
BioGRIDCTRB1
STRING (EMBL)CTRB1
ZODIACCTRB1
Ontologies - Pathways
QuickGOP17538
Ontology : AmiGOserine-type endopeptidase activity  serine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  digestion  serine-type peptidase activity  cobalamin metabolic process  extracellular matrix disassembly  
Ontology : EGO-EBIserine-type endopeptidase activity  serine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  digestion  serine-type peptidase activity  cobalamin metabolic process  extracellular matrix disassembly  
Pathways : KEGGPancreatic secretion    Protein digestion and absorption   
NDEx NetworkCTRB1
Atlas of Cancer Signalling NetworkCTRB1
Wikipedia pathwaysCTRB1
Orthology - Evolution
OrthoDB1504
GeneTree (enSembl)ENSG00000168925
Phylogenetic Trees/Animal Genes : TreeFamCTRB1
HOVERGENP17538
HOGENOMP17538
Homologs : HomoloGeneCTRB1
Homology/Alignments : Family Browser (UCSC)CTRB1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCTRB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CTRB1
dbVarCTRB1
ClinVarCTRB1
1000_GenomesCTRB1 
Exome Variant ServerCTRB1
ExAC (Exome Aggregation Consortium)CTRB1 (select the gene name)
Genetic variants : HAPMAP1504
Genomic Variants (DGV)CTRB1 [DGVbeta]
DECIPHERCTRB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCTRB1 
Mutations
ICGC Data PortalCTRB1 
TCGA Data PortalCTRB1 
Broad Tumor PortalCTRB1
OASIS PortalCTRB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCTRB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCTRB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CTRB1
DgiDB (Drug Gene Interaction Database)CTRB1
DoCM (Curated mutations)CTRB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CTRB1 (select a term)
intoGenCTRB1
Cancer3DCTRB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM118890   
Orphanet
MedgenCTRB1
Genetic Testing Registry CTRB1
NextProtP17538 [Medical]
TSGene1504
GENETestsCTRB1
Target ValidationCTRB1
Huge Navigator CTRB1 [HugePedia]
snp3D : Map Gene to Disease1504
BioCentury BCIQCTRB1
ClinGenCTRB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1504
Chemical/Pharm GKB GenePA27022
Clinical trialCTRB1
Miscellaneous
canSAR (ICR)CTRB1 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCTRB1
EVEXCTRB1
GoPubMedCTRB1
iHOPCTRB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:44:52 CEST 2017

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