Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CTRB2 (chymotrypsinogen B2)

Identity

Other alias-
HGNC (Hugo) CTRB2
LocusID (NCBI) 440387
Atlas_Id 62188
Location 16q23.1  [Link to chromosome band 16q23]
Location_base_pair Starts at 75237994 and ends at 75241072 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CTRB2   2522
Cards
Entrez_Gene (NCBI)CTRB2  440387  chymotrypsinogen B2
Aliases
GeneCards (Weizmann)CTRB2
Ensembl hg19 (Hinxton)ENSG00000168928 [Gene_View]  chr16:75237994-75241072 [Contig_View]  CTRB2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000168928 [Gene_View]  chr16:75237994-75241072 [Contig_View]  CTRB2 [Vega]
ICGC DataPortalENSG00000168928
TCGA cBioPortalCTRB2
AceView (NCBI)CTRB2
Genatlas (Paris)CTRB2
WikiGenes440387
SOURCE (Princeton)CTRB2
Genetics Home Reference (NIH)CTRB2
Genomic and cartography
GoldenPath hg19 (UCSC)CTRB2  -     chr16:75237994-75241072 -  16q23.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CTRB2  -     16q23.1   [Description]    (hg38-Dec_2013)
EnsemblCTRB2 - 16q23.1 [CytoView hg19]  CTRB2 - 16q23.1 [CytoView hg38]
Mapping of homologs : NCBICTRB2 [Mapview hg19]  CTRB2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK131056 AK225933 AK291822 BC073145 BP324399
RefSeq transcript (Entrez)NM_001025200
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)CTRB2
Cluster EST : UnigeneHs.632211 [ NCBI ]
CGAP (NCI)Hs.632211
Alternative Splicing GalleryENSG00000168928
Gene ExpressionCTRB2 [ NCBI-GEO ]   CTRB2 [ EBI - ARRAY_EXPRESS ]   CTRB2 [ SEEK ]   CTRB2 [ MEM ]
Gene Expression Viewer (FireBrowse)CTRB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)440387
GTEX Portal (Tissue expression)CTRB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6GPI1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6GPI1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6GPI1
Splice isoforms : SwissVarQ6GPI1
Catalytic activity : Enzyme3.4.21.1 [ Enzyme-Expasy ]   3.4.21.13.4.21.1 [ IntEnz-EBI ]   3.4.21.1 [ BRENDA ]   3.4.21.1 [ KEGG ]   
PhosPhoSitePlusQ6GPI1
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1    Peptidase_S1_AS    Peptidase_S1A    Trypsin-like_Pept_dom   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)CTRB2
DMDM Disease mutations440387
Blocks (Seattle)CTRB2
SuperfamilyQ6GPI1
Human Protein AtlasENSG00000168928
Peptide AtlasQ6GPI1
IPIIPI00742763   
Protein Interaction databases
DIP (DOE-UCLA)Q6GPI1
IntAct (EBI)Q6GPI1
FunCoupENSG00000168928
BioGRIDCTRB2
STRING (EMBL)CTRB2
ZODIACCTRB2
Ontologies - Pathways
QuickGOQ6GPI1
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  vitamin metabolic process  water-soluble vitamin metabolic process  digestion  cobalamin metabolic process  extracellular matrix disassembly  extracellular matrix organization  small molecule metabolic process  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  extracellular space  proteolysis  vitamin metabolic process  water-soluble vitamin metabolic process  digestion  cobalamin metabolic process  extracellular matrix disassembly  extracellular matrix organization  small molecule metabolic process  
NDEx NetworkCTRB2
Atlas of Cancer Signalling NetworkCTRB2
Wikipedia pathwaysCTRB2
Orthology - Evolution
OrthoDB440387
GeneTree (enSembl)ENSG00000168928
Phylogenetic Trees/Animal Genes : TreeFamCTRB2
HOVERGENQ6GPI1
HOGENOMQ6GPI1
Homologs : HomoloGeneCTRB2
Homology/Alignments : Family Browser (UCSC)CTRB2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCTRB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CTRB2
dbVarCTRB2
ClinVarCTRB2
1000_GenomesCTRB2 
Exome Variant ServerCTRB2
ExAC (Exome Aggregation Consortium)CTRB2 (select the gene name)
Genetic variants : HAPMAP440387
Genomic Variants (DGV)CTRB2 [DGVbeta]
DECIPHER (Syndromes)16:75237994-75241072  ENSG00000168928
CONAN: Copy Number AnalysisCTRB2 
Mutations
ICGC Data PortalCTRB2 
TCGA Data PortalCTRB2 
Broad Tumor PortalCTRB2
OASIS PortalCTRB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCTRB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCTRB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CTRB2
DgiDB (Drug Gene Interaction Database)CTRB2
DoCM (Curated mutations)CTRB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CTRB2 (select a term)
intoGenCTRB2
Cancer3DCTRB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCTRB2
Genetic Testing Registry CTRB2
NextProtQ6GPI1 [Medical]
TSGene440387
GENETestsCTRB2
Huge Navigator CTRB2 [HugePedia]
snp3D : Map Gene to Disease440387
BioCentury BCIQCTRB2
ClinGenCTRB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD440387
Chemical/Pharm GKB GenePA27023
Clinical trialCTRB2
Miscellaneous
canSAR (ICR)CTRB2 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCTRB2
EVEXCTRB2
GoPubMedCTRB2
iHOPCTRB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:00:40 CET 2017

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