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CTSA (cathepsin A)

Identity

Other namesGLB2
GSL
NGBE
PPCA
PPGB
HGNC (Hugo) CTSA
LocusID (NCBI) 5476
Location 20q13.12
Location_base_pair Starts at 44519591 and ends at 44527458 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CTSA   9251
Cards
Entrez_Gene (NCBI)CTSA  5476  cathepsin A
GeneCards (Weizmann)CTSA
Ensembl (Hinxton)ENSG00000064601 [Gene_View]  chr20:44519591-44527458 [Contig_View]  CTSA [Vega]
ICGC DataPortalENSG00000064601
AceView (NCBI)CTSA
Genatlas (Paris)CTSA
WikiGenes5476
SOURCE (Princeton)NM_000308 NM_001127695 NM_001167594
Genomic and cartography
GoldenPath (UCSC)CTSA  -  20q13.12   chr20:44519591-44527458 +  20q13.12   [Description]    (hg19-Feb_2009)
EnsemblCTSA - 20q13.12 [CytoView]
Mapping of homologs : NCBICTSA [Mapview]
OMIM256540   613111   
Gene and transcription
Genbank (Entrez)AB209705 AF086236 AK055177 AK097786 AK172808
RefSeq transcript (Entrez)NM_000308 NM_001127695 NM_001167594
RefSeq genomic (Entrez)AC_000152 NC_000020 NC_018931 NG_008291 NT_011362 NW_001838666 NW_004929418
Consensus coding sequences : CCDS (NCBI)CTSA
Cluster EST : UnigeneHs.609336 [ NCBI ]
CGAP (NCI)Hs.609336
Alternative Splicing : Fast-db (Paris)GSHG0018793
Alternative Splicing GalleryENSG00000064601
Gene ExpressionCTSA [ NCBI-GEO ]     CTSA [ SEEK ]   CTSA [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP10619 (Uniprot)
NextProtP10619  [Medical]
With graphics : InterProP10619
Splice isoforms : SwissVarP10619 (Swissvar)
Catalytic activity : Enzyme3.4.16.5 [ Enzyme-Expasy ]   3.4.16.53.4.16.5 [ IntEnz-EBI ]   3.4.16.5 [ BRENDA ]   3.4.16.5 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)CARBOXYPEPT_SER_HIS (PS00560)    CARBOXYPEPT_SER_SER (PS00131)   
Domains : Interpro (EBI)AB_hydrolase    Peptidase_S10    Peptidase_S10_AS   
Related proteins : CluSTrP10619
Domain families : Pfam (Sanger)Peptidase_S10 (PF00450)   
Domain families : Pfam (NCBI)pfam00450   
DMDM Disease mutations5476
Blocks (Seattle)P10619
PDB (SRS)1IVY    3BP4    3BP7    3BXN    4AZ0    4AZ3    4CI9    4CIA    4CIB    4MWS    4MWT   
PDB (PDBSum)1IVY    3BP4    3BP7    3BXN    4AZ0    4AZ3    4CI9    4CIA    4CIB    4MWS    4MWT   
PDB (IMB)1IVY    3BP4    3BP7    3BXN    4AZ0    4AZ3    4CI9    4CIA    4CIB    4MWS    4MWT   
PDB (RSDB)1IVY    3BP4    3BP7    3BXN    4AZ0    4AZ3    4CI9    4CIA    4CIB    4MWS    4MWT   
Human Protein AtlasENSG00000064601
Peptide AtlasP10619
HPRD02020
IPIIPI00021794   IPI00641157   IPI00640525   IPI00643801   
Protein Interaction databases
DIP (DOE-UCLA)P10619
IntAct (EBI)P10619
FunCoupENSG00000064601
BioGRIDCTSA
IntegromeDBCTSA
STRING (EMBL)CTSA
Ontologies - Pathways
QuickGOP10619
Ontology : AmiGOcarboxypeptidase activity  serine-type carboxypeptidase activity  nucleus  nucleolus  lysosome  endoplasmic reticulum  proteolysis  sphingolipid metabolic process  glycosphingolipid metabolic process  intracellular protein transport  enzyme activator activity  membrane  positive regulation of catalytic activity  lysosomal lumen  intracellular membrane-bounded organelle  small molecule metabolic process  extracellular vesicular exosome  
Ontology : EGO-EBIcarboxypeptidase activity  serine-type carboxypeptidase activity  nucleus  nucleolus  lysosome  endoplasmic reticulum  proteolysis  sphingolipid metabolic process  glycosphingolipid metabolic process  intracellular protein transport  enzyme activator activity  membrane  positive regulation of catalytic activity  lysosomal lumen  intracellular membrane-bounded organelle  small molecule metabolic process  extracellular vesicular exosome  
Pathways : KEGGLysosome    Renin-angiotensin system   
Protein Interaction DatabaseCTSA
Wikipedia pathwaysCTSA
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CTSA
SNP (GeneSNP Utah)CTSA
SNP : HGBaseCTSA
Genetic variants : HAPMAPCTSA
1000_GenomesCTSA 
ICGC programENSG00000064601 
CONAN: Copy Number AnalysisCTSA 
Somatic Mutations in Cancer : COSMICCTSA 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)20:44519591-44527458
Mutations and Diseases : HGMDCTSA
OMIM256540    613111   
MedgenCTSA
GENETestsCTSA
Disease Genetic AssociationCTSA
Huge Navigator CTSA [HugePedia]  CTSA [HugeCancerGEM]
Genomic VariantsCTSA  CTSA [DGVbeta]
Exome VariantCTSA
dbVarCTSA
ClinVarCTSA
snp3D : Map Gene to Disease5476
General knowledge
Homologs : HomoloGeneCTSA
Homology/Alignments : Family Browser (UCSC)CTSA
Phylogenetic Trees/Animal Genes : TreeFamCTSA
Chemical/Protein Interactions : CTD5476
Chemical/Pharm GKB GenePA33572
Clinical trialCTSA
Cancer Resource (Charite)ENSG00000064601
Other databases
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
CoreMineCTSA
GoPubMedCTSA
iHOPCTSA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 17:20:40 CET 2014

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