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CTSG (cathepsin G)

Identity

Alias_symbol (synonym)CG
Other aliasCATG
HGNC (Hugo) CTSG
LocusID (NCBI) 1511
Atlas_Id 40205
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 24573518 and ends at 24576260 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CTSG   2532
Cards
Entrez_Gene (NCBI)CTSG  1511  cathepsin G
AliasesCATG; CG
GeneCards (Weizmann)CTSG
Ensembl hg19 (Hinxton)ENSG00000100448 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100448 [Gene_View]  chr14:24573518-24576260 [Contig_View]  CTSG [Vega]
ICGC DataPortalENSG00000100448
TCGA cBioPortalCTSG
AceView (NCBI)CTSG
Genatlas (Paris)CTSG
WikiGenes1511
SOURCE (Princeton)CTSG
Genetics Home Reference (NIH)CTSG
Genomic and cartography
GoldenPath hg38 (UCSC)CTSG  -     chr14:24573518-24576260 -  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CTSG  -     14q12   [Description]    (hg19-Feb_2009)
EnsemblCTSG - 14q12 [CytoView hg19]  CTSG - 14q12 [CytoView hg38]
Mapping of homologs : NCBICTSG [Mapview hg19]  CTSG [Mapview hg38]
OMIM116830   
Gene and transcription
Genbank (Entrez)AI272833 AK225914 BC014460 CR456807 CR541704
RefSeq transcript (Entrez)NM_001911
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CTSG
Cluster EST : UnigeneHs.421724 [ NCBI ]
CGAP (NCI)Hs.421724
Alternative Splicing GalleryENSG00000100448
Gene ExpressionCTSG [ NCBI-GEO ]   CTSG [ EBI - ARRAY_EXPRESS ]   CTSG [ SEEK ]   CTSG [ MEM ]
Gene Expression Viewer (FireBrowse)CTSG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1511
GTEX Portal (Tissue expression)CTSG
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08311   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08311  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08311
Splice isoforms : SwissVarP08311
Catalytic activity : Enzyme3.4.21.20 [ Enzyme-Expasy ]   3.4.21.203.4.21.20 [ IntEnz-EBI ]   3.4.21.20 [ BRENDA ]   3.4.21.20 [ KEGG ]   
PhosPhoSitePlusP08311
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)CTSG
DMDM Disease mutations1511
Blocks (Seattle)CTSG
PDB (SRS)1AU8    1CGH    1KYN    1T32   
PDB (PDBSum)1AU8    1CGH    1KYN    1T32   
PDB (IMB)1AU8    1CGH    1KYN    1T32   
PDB (RSDB)1AU8    1CGH    1KYN    1T32   
Structural Biology KnowledgeBase1AU8    1CGH    1KYN    1T32   
SCOP (Structural Classification of Proteins)1AU8    1CGH    1KYN    1T32   
CATH (Classification of proteins structures)1AU8    1CGH    1KYN    1T32   
SuperfamilyP08311
Human Protein AtlasENSG00000100448
Peptide AtlasP08311
HPRD00289
IPIIPI00028064   
Protein Interaction databases
DIP (DOE-UCLA)P08311
IntAct (EBI)P08311
FunCoupENSG00000100448
BioGRIDCTSG
STRING (EMBL)CTSG
ZODIACCTSG
Ontologies - Pathways
QuickGOP08311
Ontology : AmiGOangiotensin maturation  serine-type endopeptidase activity  serine-type endopeptidase activity  serine-type endopeptidase activity  protein binding  extracellular region  extracellular space  nucleus  plasma membrane  plasma membrane  protein phosphorylation  proteolysis  immune response  heparin binding  peptidase activity  serine-type peptidase activity  cell surface  cytoplasmic stress granule  protein processing  antimicrobial humoral response  antibacterial humoral response  extracellular matrix disassembly  secretory granule  extracellular matrix  azurophil granule lumen  neutrophil degranulation  negative regulation of growth of symbiont in host  cellular protein metabolic process  positive regulation of immune response  defense response to Gram-negative bacterium  defense response to fungus  extracellular exosome  neutrophil mediated killing of gram-positive bacterium  cellular response to lipopolysaccharide  
Ontology : EGO-EBIangiotensin maturation  serine-type endopeptidase activity  serine-type endopeptidase activity  serine-type endopeptidase activity  protein binding  extracellular region  extracellular space  nucleus  plasma membrane  plasma membrane  protein phosphorylation  proteolysis  immune response  heparin binding  peptidase activity  serine-type peptidase activity  cell surface  cytoplasmic stress granule  protein processing  antimicrobial humoral response  antibacterial humoral response  extracellular matrix disassembly  secretory granule  extracellular matrix  azurophil granule lumen  neutrophil degranulation  negative regulation of growth of symbiont in host  cellular protein metabolic process  positive regulation of immune response  defense response to Gram-negative bacterium  defense response to fungus  extracellular exosome  neutrophil mediated killing of gram-positive bacterium  cellular response to lipopolysaccharide  
Pathways : KEGGNeuroactive ligand-receptor interaction    Lysosome    Renin-angiotensin system    Amoebiasis    Systemic lupus erythematosus   
NDEx NetworkCTSG
Atlas of Cancer Signalling NetworkCTSG
Wikipedia pathwaysCTSG
Orthology - Evolution
OrthoDB1511
GeneTree (enSembl)ENSG00000100448
Phylogenetic Trees/Animal Genes : TreeFamCTSG
HOVERGENP08311
HOGENOMP08311
Homologs : HomoloGeneCTSG
Homology/Alignments : Family Browser (UCSC)CTSG
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCTSG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CTSG
dbVarCTSG
ClinVarCTSG
1000_GenomesCTSG 
Exome Variant ServerCTSG
ExAC (Exome Aggregation Consortium)CTSG (select the gene name)
Genetic variants : HAPMAP1511
Genomic Variants (DGV)CTSG [DGVbeta]
DECIPHERCTSG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCTSG 
Mutations
ICGC Data PortalCTSG 
TCGA Data PortalCTSG 
Broad Tumor PortalCTSG
OASIS PortalCTSG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCTSG  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCTSG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CTSG
DgiDB (Drug Gene Interaction Database)CTSG
DoCM (Curated mutations)CTSG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CTSG (select a term)
intoGenCTSG
Cancer3DCTSG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM116830   
Orphanet
MedgenCTSG
Genetic Testing Registry CTSG
NextProtP08311 [Medical]
TSGene1511
GENETestsCTSG
Target ValidationCTSG
Huge Navigator CTSG [HugePedia]
snp3D : Map Gene to Disease1511
BioCentury BCIQCTSG
ClinGenCTSG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1511
Chemical/Pharm GKB GenePA27032
Clinical trialCTSG
Miscellaneous
canSAR (ICR)CTSG (select the gene name)
Probes
Litterature
PubMed118 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCTSG
EVEXCTSG
GoPubMedCTSG
iHOPCTSG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:58:55 CEST 2017

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