Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CTSG (cathepsin G)

Identity

Alias (NCBI)CATG
CG
HGNC (Hugo) CTSG
HGNC Alias symbCG
LocusID (NCBI) 1511
Atlas_Id 40205
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 24573518 and ends at 24576250 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)CTSG   2532
Cards
Entrez_Gene (NCBI)CTSG    cathepsin G
AliasesCATG; CG
GeneCards (Weizmann)CTSG
Ensembl hg19 (Hinxton)ENSG00000100448 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100448 [Gene_View]  ENSG00000100448 [Sequence]  chr14:24573518-24576250 [Contig_View]  CTSG [Vega]
ICGC DataPortalENSG00000100448
TCGA cBioPortalCTSG
AceView (NCBI)CTSG
Genatlas (Paris)CTSG
SOURCE (Princeton)CTSG
Genetics Home Reference (NIH)CTSG
Genomic and cartography
GoldenPath hg38 (UCSC)CTSG  -     chr14:24573518-24576250 -  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CTSG  -     14q12   [Description]    (hg19-Feb_2009)
GoldenPathCTSG - 14q12 [CytoView hg19]  CTSG - 14q12 [CytoView hg38]
ImmunoBaseENSG00000100448
genome Data Viewer NCBICTSG [Mapview hg19]  
OMIM116830   
Gene and transcription
Genbank (Entrez)AI272833 AK225914 BC014460 CR456807 CR541704
RefSeq transcript (Entrez)NM_001911
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CTSG
Alternative Splicing GalleryENSG00000100448
Gene ExpressionCTSG [ NCBI-GEO ]   CTSG [ EBI - ARRAY_EXPRESS ]   CTSG [ SEEK ]   CTSG [ MEM ]
Gene Expression Viewer (FireBrowse)CTSG [ Firebrowse - Broad ]
GenevisibleExpression of CTSG in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1511
GTEX Portal (Tissue expression)CTSG
Human Protein AtlasENSG00000100448-CTSG [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08311   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08311  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08311
Splice isoforms : SwissVarP08311
Catalytic activity : Enzyme3.4.21.20 [ Enzyme-Expasy ]   3.4.21.203.4.21.20 [ IntEnz-EBI ]   3.4.21.20 [ BRENDA ]   3.4.21.20 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP08311
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)CTSG
Blocks (Seattle)CTSG
PDB (RSDB)1AU8    1CGH    1KYN    1T32   
PDB Europe1AU8    1CGH    1KYN    1T32   
PDB (PDBSum)1AU8    1CGH    1KYN    1T32   
PDB (IMB)1AU8    1CGH    1KYN    1T32   
Structural Biology KnowledgeBase1AU8    1CGH    1KYN    1T32   
SCOP (Structural Classification of Proteins)1AU8    1CGH    1KYN    1T32   
CATH (Classification of proteins structures)1AU8    1CGH    1KYN    1T32   
SuperfamilyP08311
Human Protein Atlas [tissue]ENSG00000100448-CTSG [tissue]
Peptide AtlasP08311
HPRD00289
IPIIPI00028064   
Protein Interaction databases
DIP (DOE-UCLA)P08311
IntAct (EBI)P08311
BioGRIDCTSG
STRING (EMBL)CTSG
ZODIACCTSG
Ontologies - Pathways
QuickGOP08311
Ontology : AmiGOangiotensin maturation  serine-type endopeptidase activity  serine-type endopeptidase activity  protein binding  extracellular region  extracellular region  extracellular space  nucleus  cytoplasm  plasma membrane  plasma membrane  protein phosphorylation  proteolysis  immune response  heparin binding  peptidase activity  serine-type peptidase activity  cell surface  cytoplasmic stress granule  antimicrobial humoral response  antibacterial humoral response  extracellular matrix disassembly  secretory granule  azurophil granule lumen  neutrophil degranulation  cellular protein metabolic process  positive regulation of immune response  defense response to Gram-negative bacterium  defense response to fungus  collagen-containing extracellular matrix  collagen-containing extracellular matrix  extracellular exosome  neutrophil mediated killing of gram-positive bacterium  cellular response to lipopolysaccharide  
Ontology : EGO-EBIangiotensin maturation  serine-type endopeptidase activity  serine-type endopeptidase activity  protein binding  extracellular region  extracellular region  extracellular space  nucleus  cytoplasm  plasma membrane  plasma membrane  protein phosphorylation  proteolysis  immune response  heparin binding  peptidase activity  serine-type peptidase activity  cell surface  cytoplasmic stress granule  antimicrobial humoral response  antibacterial humoral response  extracellular matrix disassembly  secretory granule  azurophil granule lumen  neutrophil degranulation  cellular protein metabolic process  positive regulation of immune response  defense response to Gram-negative bacterium  defense response to fungus  collagen-containing extracellular matrix  collagen-containing extracellular matrix  extracellular exosome  neutrophil mediated killing of gram-positive bacterium  cellular response to lipopolysaccharide  
Pathways : KEGGNeuroactive ligand-receptor interaction    Lysosome    Renin-angiotensin system    Amoebiasis    Systemic lupus erythematosus   
NDEx NetworkCTSG
Atlas of Cancer Signalling NetworkCTSG
Wikipedia pathwaysCTSG
Orthology - Evolution
OrthoDB1511
GeneTree (enSembl)ENSG00000100448
Phylogenetic Trees/Animal Genes : TreeFamCTSG
HOGENOMP08311
Homologs : HomoloGeneCTSG
Homology/Alignments : Family Browser (UCSC)CTSG
Gene fusions - Rearrangements
Fusion : QuiverCTSG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCTSG [hg38]
dbVarCTSG
ClinVarCTSG
MonarchCTSG
1000_GenomesCTSG 
Exome Variant ServerCTSG
GNOMAD BrowserENSG00000100448
Varsome BrowserCTSG
Genomic Variants (DGV)CTSG [DGVbeta]
DECIPHERCTSG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCTSG 
Mutations
ICGC Data PortalCTSG 
TCGA Data PortalCTSG 
Broad Tumor PortalCTSG
OASIS PortalCTSG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCTSG  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCTSG
Mutations and Diseases : HGMDCTSG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CTSG
DgiDB (Drug Gene Interaction Database)CTSG
DoCM (Curated mutations)CTSG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CTSG (select a term)
intoGenCTSG
Cancer3DCTSG(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM116830   
Orphanet
DisGeNETCTSG
MedgenCTSG
Genetic Testing Registry CTSG
NextProtP08311 [Medical]
GENETestsCTSG
Target ValidationCTSG
Huge Navigator CTSG [HugePedia]
ClinGenCTSG
Clinical trials, drugs, therapy
MyCancerGenomeCTSG
Protein Interactions : CTD
Pharm GKB GenePA27032
Pharm GKB PathwaysPA165110622   PA2023   
PharosP08311
Clinical trialCTSG
Miscellaneous
canSAR (ICR)CTSG (select the gene name)
HarmonizomeCTSG
DataMed IndexCTSG
Probes
Litterature
PubMed137 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCTSG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:11:52 CET 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.