Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CTSW (cathepsin W)

Identity

Alias_namescathepsin W (lymphopain)
Other aliasLYPN
HGNC (Hugo) CTSW
LocusID (NCBI) 1521
Atlas_Id 62194
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 65879813 and ends at 65883741 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LRRC16A (6p22.2) / CTSW (11q13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CTSW   2546
Cards
Entrez_Gene (NCBI)CTSW  1521  cathepsin W
AliasesLYPN
GeneCards (Weizmann)CTSW
Ensembl hg19 (Hinxton)ENSG00000172543 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172543 [Gene_View]  ENSG00000172543 [Sequence]  chr11:65879813-65883741 [Contig_View]  CTSW [Vega]
ICGC DataPortalENSG00000172543
TCGA cBioPortalCTSW
AceView (NCBI)CTSW
Genatlas (Paris)CTSW
WikiGenes1521
SOURCE (Princeton)CTSW
Genetics Home Reference (NIH)CTSW
Genomic and cartography
GoldenPath hg38 (UCSC)CTSW  -     chr11:65879813-65883741 +  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CTSW  -     11q13.1   [Description]    (hg19-Feb_2009)
GoldenPathCTSW - 11q13.1 [CytoView hg19]  CTSW - 11q13.1 [CytoView hg38]
ImmunoBaseENSG00000172543
Mapping of homologs : NCBICTSW [Mapview hg19]  CTSW [Mapview hg38]
OMIM602364   
Gene and transcription
Genbank (Entrez)AF013611 BC035637 BC048255 BI833187 BM996548
RefSeq transcript (Entrez)NM_001335
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CTSW
Alternative Splicing GalleryENSG00000172543
Gene ExpressionCTSW [ NCBI-GEO ]   CTSW [ EBI - ARRAY_EXPRESS ]   CTSW [ SEEK ]   CTSW [ MEM ]
Gene Expression Viewer (FireBrowse)CTSW [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1521
GTEX Portal (Tissue expression)CTSW
Human Protein AtlasENSG00000172543-CTSW [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP56202   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP56202  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP56202
Splice isoforms : SwissVarP56202
Catalytic activity : Enzyme3.4.22.- [ Enzyme-Expasy ]   3.4.22.-3.4.22.- [ IntEnz-EBI ]   3.4.22.- [ BRENDA ]   3.4.22.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP56202
Domaine pattern : Prosite (Expaxy)THIOL_PROTEASE_ASN (PS00640)    THIOL_PROTEASE_HIS (PS00639)   
Domains : Interpro (EBI)Cathepsin_W    Papain-like_cys_pep_sf    Pept_asp_AS    Pept_his_AS    Peptidase_C1A_C    Peptidase_C1A_papain-like    Prot_inhib_I29   
Domain families : Pfam (Sanger)Inhibitor_I29 (PF08246)    Peptidase_C1 (PF00112)   
Domain families : Pfam (NCBI)pfam08246    pfam00112   
Domain families : Smart (EMBL)Inhibitor_I29 (SM00848)  Pept_C1 (SM00645)  
Conserved Domain (NCBI)CTSW
DMDM Disease mutations1521
Blocks (Seattle)CTSW
SuperfamilyP56202
Human Protein Atlas [tissue]ENSG00000172543-CTSW [tissue]
Peptide AtlasP56202
HPRD03840
IPIIPI00328978   IPI00984532   IPI00983675   
Protein Interaction databases
DIP (DOE-UCLA)P56202
IntAct (EBI)P56202
FunCoupENSG00000172543
BioGRIDCTSW
STRING (EMBL)CTSW
ZODIACCTSW
Ontologies - Pathways
QuickGOP56202
Ontology : AmiGOplatelet degranulation  cysteine-type endopeptidase activity  extracellular region  extracellular space  lysosome  endoplasmic reticulum  immune response  cysteine-type peptidase activity  membrane  platelet dense granule lumen  proteolysis involved in cellular protein catabolic process  
Ontology : EGO-EBIplatelet degranulation  cysteine-type endopeptidase activity  extracellular region  extracellular space  lysosome  endoplasmic reticulum  immune response  cysteine-type peptidase activity  membrane  platelet dense granule lumen  proteolysis involved in cellular protein catabolic process  
NDEx NetworkCTSW
Atlas of Cancer Signalling NetworkCTSW
Wikipedia pathwaysCTSW
Orthology - Evolution
OrthoDB1521
GeneTree (enSembl)ENSG00000172543
Phylogenetic Trees/Animal Genes : TreeFamCTSW
HOGENOMP56202
Homologs : HomoloGeneCTSW
Homology/Alignments : Family Browser (UCSC)CTSW
Gene fusions - Rearrangements
Fusion : QuiverCTSW
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCTSW [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CTSW
dbVarCTSW
ClinVarCTSW
1000_GenomesCTSW 
Exome Variant ServerCTSW
ExAC (Exome Aggregation Consortium)ENSG00000172543
GNOMAD BrowserENSG00000172543
Varsome BrowserCTSW
Genetic variants : HAPMAP1521
Genomic Variants (DGV)CTSW [DGVbeta]
DECIPHERCTSW [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCTSW 
Mutations
ICGC Data PortalCTSW 
TCGA Data PortalCTSW 
Broad Tumor PortalCTSW
OASIS PortalCTSW [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCTSW  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCTSW
Mutations and Diseases : HGMDCTSW
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CTSW
DgiDB (Drug Gene Interaction Database)CTSW
DoCM (Curated mutations)CTSW (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CTSW (select a term)
intoGenCTSW
Cancer3DCTSW(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602364   
Orphanet
DisGeNETCTSW
MedgenCTSW
Genetic Testing Registry CTSW
NextProtP56202 [Medical]
TSGene1521
GENETestsCTSW
Target ValidationCTSW
Huge Navigator CTSW [HugePedia]
snp3D : Map Gene to Disease1521
BioCentury BCIQCTSW
ClinGenCTSW
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1521
Chemical/Pharm GKB GenePA27042
Clinical trialCTSW
Miscellaneous
canSAR (ICR)CTSW (select the gene name)
HarmonizomeCTSW
DataMed IndexCTSW
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCTSW
EVEXCTSW
GoPubMedCTSW
iHOPCTSW
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sun May 10 11:28:52 CEST 2020
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.