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CTTNBP2 (cortactin binding protein 2)

Identity

Alias (NCBI)C7orf8
CORTBP2
Orf4
HGNC (Hugo) CTTNBP2
HGNC Alias symbKIAA1758
Orf4
HGNC Previous nameCORTBP2
 C7orf8
HGNC Previous namecortactin binding protein 2
LocusID (NCBI) 83992
Atlas_Id 62195
Location 7q31.31  [Link to chromosome band 7q31]
Location_base_pair Starts at 117710651 and ends at 117873441 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CTTNBP2 (7q31.2) / CTTNBP2 (7q31.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)CTTNBP2   15679
Cards
Entrez_Gene (NCBI)CTTNBP2    cortactin binding protein 2
AliasesC7orf8; CORTBP2; Orf4
GeneCards (Weizmann)CTTNBP2
Ensembl hg19 (Hinxton)ENSG00000077063 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000077063 [Gene_View]  ENSG00000077063 [Sequence]  chr7:117710651-117873441 [Contig_View]  CTTNBP2 [Vega]
ICGC DataPortalENSG00000077063
TCGA cBioPortalCTTNBP2
AceView (NCBI)CTTNBP2
Genatlas (Paris)CTTNBP2
SOURCE (Princeton)CTTNBP2
Genetics Home Reference (NIH)CTTNBP2
Genomic and cartography
GoldenPath hg38 (UCSC)CTTNBP2  -     chr7:117710651-117873441 -  7q31.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CTTNBP2  -     7q31.31   [Description]    (hg19-Feb_2009)
GoldenPathCTTNBP2 - 7q31.31 [CytoView hg19]  CTTNBP2 - 7q31.31 [CytoView hg38]
ImmunoBaseENSG00000077063
Genome Data Viewer NCBICTTNBP2 [Mapview hg19]  
OMIM609772   
Gene and transcription
Genbank (Entrez)AB051545 AF377960 AK091548 AK096565 AK308081
RefSeq transcript (Entrez)NM_001363349 NM_001363350 NM_001363351 NM_033427
Consensus coding sequences : CCDS (NCBI)CTTNBP2
Gene ExpressionCTTNBP2 [ NCBI-GEO ]   CTTNBP2 [ EBI - ARRAY_EXPRESS ]   CTTNBP2 [ SEEK ]   CTTNBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)CTTNBP2 [ Firebrowse - Broad ]
GenevisibleExpression of CTTNBP2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83992
GTEX Portal (Tissue expression)CTTNBP2
Human Protein AtlasENSG00000077063-CTTNBP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WZ74   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WZ74  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WZ74
PhosPhoSitePlusQ8WZ74
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    Ankyrin_rpt-contain_sf    Cortactin-binding_p2_N   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    CortBP2 (PF09727)   
Domain families : Pfam (NCBI)pfam12796    pfam09727   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)CTTNBP2
SuperfamilyQ8WZ74
AlphaFold pdb e-kbQ8WZ74   
Human Protein Atlas [tissue]ENSG00000077063-CTTNBP2 [tissue]
HPRD09890
Protein Interaction databases
DIP (DOE-UCLA)Q8WZ74
IntAct (EBI)Q8WZ74
BioGRIDCTTNBP2
STRING (EMBL)CTTNBP2
ZODIACCTTNBP2
Ontologies - Pathways
QuickGOQ8WZ74
Ontology : AmiGOprotein binding  cell cortex  brain development  synaptic vesicle  SH3 domain binding  dendritic spine  postsynaptic actin cytoskeleton  glutamatergic synapse  regulation of modification of postsynaptic actin cytoskeleton  
Ontology : EGO-EBIprotein binding  cell cortex  brain development  synaptic vesicle  SH3 domain binding  dendritic spine  postsynaptic actin cytoskeleton  glutamatergic synapse  regulation of modification of postsynaptic actin cytoskeleton  
NDEx NetworkCTTNBP2
Atlas of Cancer Signalling NetworkCTTNBP2
Wikipedia pathwaysCTTNBP2
Orthology - Evolution
OrthoDB83992
GeneTree (enSembl)ENSG00000077063
Phylogenetic Trees/Animal Genes : TreeFamCTTNBP2
Homologs : HomoloGeneCTTNBP2
Homology/Alignments : Family Browser (UCSC)CTTNBP2
Gene fusions - Rearrangements
Fusion : QuiverCTTNBP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCTTNBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CTTNBP2
dbVarCTTNBP2
ClinVarCTTNBP2
MonarchCTTNBP2
1000_GenomesCTTNBP2 
Exome Variant ServerCTTNBP2
GNOMAD BrowserENSG00000077063
Varsome BrowserCTTNBP2
ACMGCTTNBP2 variants
VarityQ8WZ74
Genomic Variants (DGV)CTTNBP2 [DGVbeta]
DECIPHERCTTNBP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCTTNBP2 
Mutations
ICGC Data PortalCTTNBP2 
TCGA Data PortalCTTNBP2 
Broad Tumor PortalCTTNBP2
OASIS PortalCTTNBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCTTNBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCTTNBP2
Mutations and Diseases : HGMDCTTNBP2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCTTNBP2
DgiDB (Drug Gene Interaction Database)CTTNBP2
DoCM (Curated mutations)CTTNBP2
CIViC (Clinical Interpretations of Variants in Cancer)CTTNBP2
Cancer3DCTTNBP2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609772   
Orphanet
DisGeNETCTTNBP2
MedgenCTTNBP2
Genetic Testing Registry CTTNBP2
NextProtQ8WZ74 [Medical]
GENETestsCTTNBP2
Target ValidationCTTNBP2
Huge Navigator CTTNBP2 [HugePedia]
ClinGenCTTNBP2
Clinical trials, drugs, therapy
MyCancerGenomeCTTNBP2
Protein Interactions : CTDCTTNBP2
Pharm GKB GenePA26774
PharosQ8WZ74
Clinical trialCTTNBP2
Miscellaneous
canSAR (ICR)CTTNBP2
HarmonizomeCTTNBP2
DataMed IndexCTTNBP2
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCTTNBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:47:05 CEST 2021
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