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CUL5 (cullin 5)

Identity

Other namesVACM-1
VACM1
HGNC (Hugo) CUL5
LocusID (NCBI) 8065
Location 11q22.3
Location_base_pair Starts at 107879408 and ends at 107978488 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CUL5   2556
Cards
Entrez_Gene (NCBI)CUL5  8065  cullin 5
GeneCards (Weizmann)CUL5
Ensembl (Hinxton)ENSG00000166266 [Gene_View]  chr11:107879408-107978488 [Contig_View]  CUL5 [Vega]
AceView (NCBI)CUL5
Genatlas (Paris)CUL5
WikiGenes8065
SOURCE (Princeton)NM_003478
Genomic and cartography
GoldenPath (UCSC)CUL5  -  11q22.3   chr11:107879408-107978488 +  11q22.3   [Description]    (hg19-Feb_2009)
EnsemblCUL5 - 11q22.3 [CytoView]
Mapping of homologs : NCBICUL5 [Mapview]
OMIM601741   
Gene and transcription
Genbank (Entrez)AA099369 AA403092 AA471067 AF017061 AF327710
RefSeq transcript (Entrez)NM_003478
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NT_033899 NW_001838042 NW_004929381
Consensus coding sequences : CCDS (NCBI)CUL5
Cluster EST : UnigeneHs.440320 [ NCBI ]
CGAP (NCI)Hs.440320
Alternative Splicing : Fast-db (Paris)GSHG0005220
Alternative Splicing GalleryENSG00000166266
Gene ExpressionCUL5 [ NCBI-GEO ]     CUL5 [ SEEK ]   CUL5 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ93034 (Uniprot)
NextProtQ93034  [Medical]
With graphics : InterProQ93034
Splice isoforms : SwissVarQ93034 (Swissvar)
Domaine pattern : Prosite (Expaxy)CULLIN_1 (PS01256)    CULLIN_2 (PS50069)   
Domains : Interpro (EBI)Cullin_CS    Cullin_homology    Cullin_N    Cullin_neddylation_domain    Cullin_repeat-like_dom    WHTH_DNA-bd_dom   
Related proteins : CluSTrQ93034
Domain families : Pfam (Sanger)Cullin (PF00888)    Cullin_Nedd8 (PF10557)   
Domain families : Pfam (NCBI)pfam00888    pfam10557   
Domain families : Smart (EMBL)CULLIN (SM00182)  Cullin_Nedd8 (SM00884)  
DMDM Disease mutations8065
Blocks (Seattle)Q93034
PDB (SRS)3DPL    3DQV   
PDB (PDBSum)3DPL    3DQV   
PDB (IMB)3DPL    3DQV   
PDB (RSDB)3DPL    3DQV   
Human Protein AtlasENSG00000166266
Peptide AtlasQ93034
HPRD03444
IPIIPI00216003   IPI00978224   IPI00979455   
Protein Interaction databases
DIP (DOE-UCLA)Q93034
IntAct (EBI)Q93034
FunCoupENSG00000166266
BioGRIDCUL5
InParanoidQ93034
Interologous Interaction database Q93034
IntegromeDBCUL5
STRING (EMBL)CUL5
Ontologies - Pathways
Ontology : AmiGOG1/S transition of mitotic cell cycle  receptor activity  calcium channel activity  protein binding  nucleus  cytosol  plasma membrane  ubiquitin-dependent protein catabolic process  response to osmotic stress  cell cycle arrest  cell proliferation  negative regulation of cell proliferation  viral process  protein ubiquitination  modulation by virus of host morphology or physiology  Cul5-RING ubiquitin ligase complex  ubiquitin protein ligase binding  cytosolic calcium ion homeostasis  calcium ion transmembrane transport  intrinsic apoptotic signaling pathway  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  receptor activity  calcium channel activity  protein binding  nucleus  cytosol  plasma membrane  ubiquitin-dependent protein catabolic process  response to osmotic stress  cell cycle arrest  cell proliferation  negative regulation of cell proliferation  viral process  protein ubiquitination  modulation by virus of host morphology or physiology  Cul5-RING ubiquitin ligase complex  ubiquitin protein ligase binding  cytosolic calcium ion homeostasis  calcium ion transmembrane transport  intrinsic apoptotic signaling pathway  
Pathways : KEGGUbiquitin mediated proteolysis   
REACTOMECUL5
Protein Interaction DatabaseCUL5
Wikipedia pathwaysCUL5
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CUL5
SNP (GeneSNP Utah)CUL5
SNP : HGBaseCUL5
Genetic variants : HAPMAPCUL5
1000_GenomesCUL5 
ICGC programENSG00000166266 
Somatic Mutations in Cancer : COSMICCUL5 
CONAN: Copy Number AnalysisCUL5 
Mutations and Diseases : HGMDCUL5
OMIM601741   
GENETestsCUL5
Disease Genetic AssociationCUL5
Huge Navigator CUL5 [HugePedia]  CUL5 [HugeCancerGEM]
Genomic VariantsCUL5  CUL5 [DGVbeta]
Exome VariantCUL5
dbVarCUL5
ClinVarCUL5
snp3D : Map Gene to Disease8065
General knowledge
Homologs : HomoloGeneCUL5
Homology/Alignments : Family Browser (UCSC)CUL5
Phylogenetic Trees/Animal Genes : TreeFamCUL5
Chemical/Protein Interactions : CTD8065
Chemical/Pharm GKB GenePA27052
Clinical trialCUL5
Cancer Resource (Charite)ENSG00000166266
Other databases
Probes
Litterature
PubMed123 Pubmed reference(s) in Entrez
CoreMineCUL5
iHOPCUL5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 16:46:59 CEST 2014

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