Identity
HGNC
LOCATION
11q22.3
LOCUSID
ALIAS
CUL-5,VACM-1,VACM1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8065
MIM: 601741
HGNC: 2556
Ensembl: ENSG00000166266
Variants:
dbSNP: 8065
ClinVar: 8065
TCGA: ENSG00000166266
COSMIC: CUL5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166266 | ENST00000393094 | Q93034 |
| ENSG00000166266 | ENST00000531427 | Q93034 |
| ENSG00000166266 | ENST00000532064 | E9PP19 |
| ENSG00000166266 | ENST00000532782 | H0YCA0 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35293963 | 2022 | Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration. | 8 |
| 35293963 | 2022 | Ubiquitylation by Rab40b/Cul5 regulates Rap2 localization and activity during cell migration. | 8 |
| 33412308 | 2021 | Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway. | 15 |
| 33712558 | 2021 | Cullin-5 neddylation-mediated NOXA degradation is enhanced by PRDX1 oligomers in colorectal cancer. | 12 |
| 33999101 | 2021 | Rab40-Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration. | 11 |
| 34415831 | 2021 | Cullin-5 (CUL5) as a potential prognostic marker in a pan-cancer analysis of human tumors. | 8 |
| 33412308 | 2021 | Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway. | 15 |
| 33712558 | 2021 | Cullin-5 neddylation-mediated NOXA degradation is enhanced by PRDX1 oligomers in colorectal cancer. | 12 |
| 33999101 | 2021 | Rab40-Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration. | 11 |
| 34415831 | 2021 | Cullin-5 (CUL5) as a potential prognostic marker in a pan-cancer analysis of human tumors. | 8 |
| 31898233 | 2020 | Cullin RING Ligase 5 (CRL-5): Neddylation Activation and Biological Functions. | 15 |
| 33099949 | 2020 | miR-19a promotes the metastasis and EMT through CUL5 in prostate cancer cell line PC3. | 6 |
| 31898233 | 2020 | Cullin RING Ligase 5 (CRL-5): Neddylation Activation and Biological Functions. | 15 |
| 33099949 | 2020 | miR-19a promotes the metastasis and EMT through CUL5 in prostate cancer cell line PC3. | 6 |
| 30521783 | 2019 | MicroRNA-19a regulates the proliferation, migration and invasion of human gastric cancer cells by targeting CUL5. | 8 |
Citation
Dessen P
CUL5 (cullin 5)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40216/cul5
