Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CUL7 (cullin 7)

Identity

Alias_namesKIAA0076
KIAA0076
Alias_symbol (synonym)dJ20C7.5
Other alias3M1
CUL-7
HGNC (Hugo) CUL7
LocusID (NCBI) 9820
Atlas_Id 49921
Location 6p21.1  [Link to chromosome band 6p21]
Location_base_pair Starts at 43037617 and ends at 43053945 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CUL7 (6p21.1) / CUL7 (6p21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CUL7   21024
Cards
Entrez_Gene (NCBI)CUL7  9820  cullin 7
Aliases3M1; CUL-7; KIAA0076; dJ20C7.5
GeneCards (Weizmann)CUL7
Ensembl hg19 (Hinxton)ENSG00000044090 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000044090 [Gene_View]  ENSG00000044090 [Sequence]  chr6:43037617-43053945 [Contig_View]  CUL7 [Vega]
ICGC DataPortalENSG00000044090
TCGA cBioPortalCUL7
AceView (NCBI)CUL7
Genatlas (Paris)CUL7
WikiGenes9820
SOURCE (Princeton)CUL7
Genetics Home Reference (NIH)CUL7
Genomic and cartography
GoldenPath hg38 (UCSC)CUL7  -     chr6:43037617-43053945 -  6p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CUL7  -     6p21.1   [Description]    (hg19-Feb_2009)
EnsemblCUL7 - 6p21.1 [CytoView hg19]  CUL7 - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBICUL7 [Mapview hg19]  CUL7 [Mapview hg38]
OMIM273750   609577   
Gene and transcription
Genbank (Entrez)AK292806 AK302668 AK307936 AK309902 BC033647
RefSeq transcript (Entrez)NM_001168370 NM_014780
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CUL7
Cluster EST : UnigeneHs.520136 [ NCBI ]
CGAP (NCI)Hs.520136
Alternative Splicing GalleryENSG00000044090
Gene ExpressionCUL7 [ NCBI-GEO ]   CUL7 [ EBI - ARRAY_EXPRESS ]   CUL7 [ SEEK ]   CUL7 [ MEM ]
Gene Expression Viewer (FireBrowse)CUL7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9820
GTEX Portal (Tissue expression)CUL7
Human Protein AtlasENSG00000044090-CUL7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14999   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14999  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14999
Splice isoforms : SwissVarQ14999
PhosPhoSitePlusQ14999
Domaine pattern : Prosite (Expaxy)CULLIN_2 (PS50069)    DOC (PS51284)   
Domains : Interpro (EBI)APC_su10/DOC_dom    ARM-type_fold    CPH_domain    CUL7    Cullin_homology    Cullin_homology_sf    Cullin_N    Cullin_neddylation_domain    Galactose-bd-like_sf    Rib_L2_dom2   
Domain families : Pfam (Sanger)ANAPC10 (PF03256)    Cul7 (PF11515)    Cullin (PF00888)   
Domain families : Pfam (NCBI)pfam03256    pfam11515    pfam00888   
Domain families : Smart (EMBL)APC10 (SM01337)  Cullin_Nedd8 (SM00884)  
Conserved Domain (NCBI)CUL7
DMDM Disease mutations9820
Blocks (Seattle)CUL7
PDB (SRS)2JNG   
PDB (PDBSum)2JNG   
PDB (IMB)2JNG   
PDB (RSDB)2JNG   
Structural Biology KnowledgeBase2JNG   
SCOP (Structural Classification of Proteins)2JNG   
CATH (Classification of proteins structures)2JNG   
SuperfamilyQ14999
Human Protein Atlas [tissue]ENSG00000044090-CUL7 [tissue]
Peptide AtlasQ14999
HPRD09901
IPIIPI00001690   IPI00955011   
Protein Interaction databases
DIP (DOE-UCLA)Q14999
IntAct (EBI)Q14999
FunCoupENSG00000044090
BioGRIDCUL7
STRING (EMBL)CUL7
ZODIACCUL7
Ontologies - Pathways
QuickGOQ14999
Ontology : AmiGOmicrotubule cytoskeleton organization  mitotic cytokinesis  vasculogenesis  epithelial to mesenchymal transition  placenta development  protein binding  anaphase-promoting complex  cytoplasm  Golgi apparatus  centrosome  cytosol  proteolysis  ubiquitin-dependent protein catabolic process  Golgi organization  regulation of mitotic nuclear division  viral process  protein ubiquitination  protein ubiquitination  protein ubiquitination  Cul7-RING ubiquitin ligase complex  ubiquitin protein ligase binding  IRE1-mediated unfolded protein response  post-translational protein modification  perinuclear region of cytoplasm  positive regulation of dendrite morphogenesis  positive regulation of dendrite morphogenesis  3M complex  
Ontology : EGO-EBImicrotubule cytoskeleton organization  mitotic cytokinesis  vasculogenesis  epithelial to mesenchymal transition  placenta development  protein binding  anaphase-promoting complex  cytoplasm  Golgi apparatus  centrosome  cytosol  proteolysis  ubiquitin-dependent protein catabolic process  Golgi organization  regulation of mitotic nuclear division  viral process  protein ubiquitination  protein ubiquitination  protein ubiquitination  Cul7-RING ubiquitin ligase complex  ubiquitin protein ligase binding  IRE1-mediated unfolded protein response  post-translational protein modification  perinuclear region of cytoplasm  positive regulation of dendrite morphogenesis  positive regulation of dendrite morphogenesis  3M complex  
Pathways : KEGGUbiquitin mediated proteolysis   
NDEx NetworkCUL7
Atlas of Cancer Signalling NetworkCUL7
Wikipedia pathwaysCUL7
Orthology - Evolution
OrthoDB9820
GeneTree (enSembl)ENSG00000044090
Phylogenetic Trees/Animal Genes : TreeFamCUL7
HOVERGENQ14999
HOGENOMQ14999
Homologs : HomoloGeneCUL7
Homology/Alignments : Family Browser (UCSC)CUL7
Gene fusions - Rearrangements
Fusion : QuiverCUL7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCUL7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CUL7
dbVarCUL7
ClinVarCUL7
1000_GenomesCUL7 
Exome Variant ServerCUL7
ExAC (Exome Aggregation Consortium)ENSG00000044090
GNOMAD BrowserENSG00000044090
Varsome BrowserCUL7
Genetic variants : HAPMAP9820
Genomic Variants (DGV)CUL7 [DGVbeta]
DECIPHERCUL7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCUL7 
Mutations
ICGC Data PortalCUL7 
TCGA Data PortalCUL7 
Broad Tumor PortalCUL7
OASIS PortalCUL7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCUL7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCUL7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CUL7
DgiDB (Drug Gene Interaction Database)CUL7
DoCM (Curated mutations)CUL7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CUL7 (select a term)
intoGenCUL7
Cancer3DCUL7(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM273750    609577   
Orphanet2393   
DisGeNETCUL7
MedgenCUL7
Genetic Testing Registry CUL7
NextProtQ14999 [Medical]
TSGene9820
GENETestsCUL7
Target ValidationCUL7
Huge Navigator CUL7 [HugePedia]
snp3D : Map Gene to Disease9820
BioCentury BCIQCUL7
ClinGenCUL7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9820
Chemical/Pharm GKB GenePA134897835
Clinical trialCUL7
Miscellaneous
canSAR (ICR)CUL7 (select the gene name)
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCUL7
EVEXCUL7
GoPubMedCUL7
iHOPCUL7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:00:59 CET 2018

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