CUX2 (cut like homeobox 2)

2015-12-01  

Identity

HGNC
LOCATION
12q24.11
LOCUSID
ALIAS
CDP2,CUTL2,DEE67,EIEE67
FUSION GENES

Other Information

Locus ID:

NCBI: 23316
MIM: 610648
HGNC: 19347
Ensembl: ENSG00000111249

Variants:

dbSNP: 23316
ClinVar: 23316
TCGA: ENSG00000111249
COSMIC: CUX2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111249ENST00000261726O14529
ENSG00000111249ENST00000397643F5GWR6

Expression (GTEx)

0
5
10
15
20

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA445941TuberculosisDiseaseClinicalAnnotationassociatedPD
PA451250rifampinChemicalClinicalAnnotationassociatedPD

References

Pubmed IDYearTitleCitations
194016822010High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.52
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18
262210322015CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage.14
193285582009Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population.11
294596762018Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation.2
296307382018The epilepsy phenotypic spectrum associated with a recurrent CUX2 variant.2
297954762018A recurrent de novo CUX2 missense variant associated with intellectual disability, seizures, and autism spectrum disorder.0
307206672019Association of FAM65B, AGBL4, and CUX2 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity: validation study in a Chinese Han population.0

Citation

Dessen P

CUX2 (cut like homeobox 2)

Atlas Genet Cytogenet Oncol Haematol. 2015-12-01

Online version: http://atlasgeneticsoncology.org/gene/55545/cux2