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CWC22 (CWC22 spliceosome associated protein homolog)

Identity

Alias_namesCWC22 spliceosome-associated protein homolog (S. cerevisiae)
CWC22 spliceosome-associated protein
CWC22 homolog, spliceosome-associated protein
Alias_symbol (synonym)KIAA1604
EIF4GL
fSAPb
NCM
Other alias
HGNC (Hugo) CWC22
LocusID (NCBI) 57703
Atlas_Id 62207
Location 2q31.3  [Link to chromosome band 2q31]
Location_base_pair Starts at 179944877 and ends at 180007053 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CWC22 (2q31.3) / CUX1 (7q22.1)CWC22 (2q31.3) / THBS1 (15q14)WNK1 (12p13.33) / CWC22 (2q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CWC22   29322
Cards
Entrez_Gene (NCBI)CWC22  57703  CWC22 spliceosome associated protein homolog
AliasesEIF4GL; NCM; fSAPb
GeneCards (Weizmann)CWC22
Ensembl hg19 (Hinxton)ENSG00000163510 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163510 [Gene_View]  chr2:179944877-180007053 [Contig_View]  CWC22 [Vega]
ICGC DataPortalENSG00000163510
TCGA cBioPortalCWC22
AceView (NCBI)CWC22
Genatlas (Paris)CWC22
WikiGenes57703
SOURCE (Princeton)CWC22
Genetics Home Reference (NIH)CWC22
Genomic and cartography
GoldenPath hg38 (UCSC)CWC22  -     chr2:179944877-180007053 -  2q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CWC22  -     2q31.3   [Description]    (hg19-Feb_2009)
EnsemblCWC22 - 2q31.3 [CytoView hg19]  CWC22 - 2q31.3 [CytoView hg38]
Mapping of homologs : NCBICWC22 [Mapview hg19]  CWC22 [Mapview hg38]
OMIM615186   
Gene and transcription
Genbank (Entrez)AB046824 AK025635 AK026978 AK123647 BC016651
RefSeq transcript (Entrez)NM_020943
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CWC22
Cluster EST : UnigeneHs.311363 [ NCBI ]
CGAP (NCI)Hs.311363
Alternative Splicing GalleryENSG00000163510
Gene ExpressionCWC22 [ NCBI-GEO ]   CWC22 [ EBI - ARRAY_EXPRESS ]   CWC22 [ SEEK ]   CWC22 [ MEM ]
Gene Expression Viewer (FireBrowse)CWC22 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57703
GTEX Portal (Tissue expression)CWC22
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCG8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCG8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCG8
Splice isoforms : SwissVarQ9HCG8
PhosPhoSitePlusQ9HCG8
Domaine pattern : Prosite (Expaxy)MI (PS51366)   
Domains : Interpro (EBI)ARM-type_fold    Initiation_fac_eIF4g_MI    MIF4-like    MIF4G-like_typ-3   
Domain families : Pfam (Sanger)MA3 (PF02847)   
Domain families : Pfam (NCBI)pfam02847   
Domain families : Smart (EMBL)MA3 (SM00544)  MIF4G (SM00543)  
Conserved Domain (NCBI)CWC22
DMDM Disease mutations57703
Blocks (Seattle)CWC22
PDB (SRS)4C9B   
PDB (PDBSum)4C9B   
PDB (IMB)4C9B   
PDB (RSDB)4C9B   
Structural Biology KnowledgeBase4C9B   
SCOP (Structural Classification of Proteins)4C9B   
CATH (Classification of proteins structures)4C9B   
SuperfamilyQ9HCG8
Human Protein AtlasENSG00000163510
Peptide AtlasQ9HCG8
HPRD17220
IPIIPI00177381   IPI00917297   
Protein Interaction databases
DIP (DOE-UCLA)Q9HCG8
IntAct (EBI)Q9HCG8
FunCoupENSG00000163510
BioGRIDCWC22
STRING (EMBL)CWC22
ZODIACCWC22
Ontologies - Pathways
QuickGOQ9HCG8
Ontology : AmiGOmRNA splicing, via spliceosome  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  protein binding  nucleoplasm  spliceosomal complex  cytosol  nuclear speck  regulation of mRNA splicing, via spliceosome  U2-type catalytic step 1 spliceosome  catalytic step 2 spliceosome  
Ontology : EGO-EBImRNA splicing, via spliceosome  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  protein binding  nucleoplasm  spliceosomal complex  cytosol  nuclear speck  regulation of mRNA splicing, via spliceosome  U2-type catalytic step 1 spliceosome  catalytic step 2 spliceosome  
NDEx NetworkCWC22
Atlas of Cancer Signalling NetworkCWC22
Wikipedia pathwaysCWC22
Orthology - Evolution
OrthoDB57703
GeneTree (enSembl)ENSG00000163510
Phylogenetic Trees/Animal Genes : TreeFamCWC22
HOVERGENQ9HCG8
HOGENOMQ9HCG8
Homologs : HomoloGeneCWC22
Homology/Alignments : Family Browser (UCSC)CWC22
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCWC22 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CWC22
dbVarCWC22
ClinVarCWC22
1000_GenomesCWC22 
Exome Variant ServerCWC22
ExAC (Exome Aggregation Consortium)CWC22 (select the gene name)
Genetic variants : HAPMAP57703
Genomic Variants (DGV)CWC22 [DGVbeta]
DECIPHERCWC22 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCWC22 
Mutations
ICGC Data PortalCWC22 
TCGA Data PortalCWC22 
Broad Tumor PortalCWC22
OASIS PortalCWC22 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCWC22  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCWC22
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CWC22
DgiDB (Drug Gene Interaction Database)CWC22
DoCM (Curated mutations)CWC22 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CWC22 (select a term)
intoGenCWC22
Cancer3DCWC22(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615186   
Orphanet
MedgenCWC22
Genetic Testing Registry CWC22
NextProtQ9HCG8 [Medical]
TSGene57703
GENETestsCWC22
Target ValidationCWC22
Huge Navigator CWC22 [HugePedia]
snp3D : Map Gene to Disease57703
BioCentury BCIQCWC22
ClinGenCWC22
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57703
Chemical/Pharm GKB GenePA164718415
Clinical trialCWC22
Miscellaneous
canSAR (ICR)CWC22 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCWC22
EVEXCWC22
GoPubMedCWC22
iHOPCWC22
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:44:56 CEST 2017

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