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CWC27 (CWC27 spliceosome associated cyclophilin)

Identity

Alias (NCBI)NY-CO-10
RPSKA
SDCCAG-10
SDCCAG10
HGNC (Hugo) CWC27
HGNC Alias symbNY-CO-10
SDCCAG-10
HGNC Previous nameSDCCAG10
HGNC Previous nameserologically defined colon cancer antigen 10
 CWC27 spliceosome-associated protein homolog (S. cerevisiae)
 CWC27 spliceosome-associated protein homolog
 CWC27 spliceosome associated protein homolog
LocusID (NCBI) 10283
Atlas_Id 42228
Location 5q12.3  [Link to chromosome band 5q12]
Location_base_pair Starts at 64768930 and ends at 65018750 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BDP1 (5q13.2) / CWC27 (5q12.3)CWC27 (5q12.3) / CWC27 (5q12.3)CWC27 (5q12.3) / RNF180 (5q12.3)
BDP1 5q13.2 / CWC27 5q12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CWC27   10664
Cards
Entrez_Gene (NCBI)CWC27    CWC27 spliceosome associated cyclophilin
AliasesNY-CO-10; RPSKA; SDCCAG-10; SDCCAG10
GeneCards (Weizmann)CWC27
Ensembl hg19 (Hinxton)ENSG00000153015 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000153015 [Gene_View]  ENSG00000153015 [Sequence]  chr5:64768930-65018750 [Contig_View]  CWC27 [Vega]
ICGC DataPortalENSG00000153015
TCGA cBioPortalCWC27
AceView (NCBI)CWC27
Genatlas (Paris)CWC27
SOURCE (Princeton)CWC27
Genetics Home Reference (NIH)CWC27
Genomic and cartography
GoldenPath hg38 (UCSC)CWC27  -     chr5:64768930-65018750 +  5q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CWC27  -     5q12.3   [Description]    (hg19-Feb_2009)
GoldenPathCWC27 - 5q12.3 [CytoView hg19]  CWC27 - 5q12.3 [CytoView hg38]
ImmunoBaseENSG00000153015
Genome Data Viewer NCBICWC27 [Mapview hg19]  
OMIM250410   617170   
Gene and transcription
Genbank (Entrez)AF039692 AF039693 AJ002573 AK225105 AK225161
RefSeq transcript (Entrez)NM_001297644 NM_001297645 NM_001318000 NM_001364478 NM_005869
Consensus coding sequences : CCDS (NCBI)CWC27
Gene ExpressionCWC27 [ NCBI-GEO ]   CWC27 [ EBI - ARRAY_EXPRESS ]   CWC27 [ SEEK ]   CWC27 [ MEM ]
Gene Expression Viewer (FireBrowse)CWC27 [ Firebrowse - Broad ]
GenevisibleExpression of CWC27 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10283
GTEX Portal (Tissue expression)CWC27
Human Protein AtlasENSG00000153015-CWC27 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UX04   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UX04  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UX04
PhosPhoSitePlusQ6UX04
Domaine pattern : Prosite (Expaxy)CSA_PPIASE_1 (PS00170)    CSA_PPIASE_2 (PS50072)   
Domains : Interpro (EBI)Cyclophilin-like_dom_sf    Cyclophilin-type_PPIase_CS    Cyclophilin-type_PPIase_dom   
Domain families : Pfam (Sanger)Pro_isomerase (PF00160)   
Domain families : Pfam (NCBI)pfam00160   
Conserved Domain (NCBI)CWC27
PDB (RSDB)2HQ6    4R3E    5Z56    5Z58    6FF4    6FF7    6YVH   
PDB Europe2HQ6    4R3E    5Z56    5Z58    6FF4    6FF7    6YVH   
PDB (PDBSum)2HQ6    4R3E    5Z56    5Z58    6FF4    6FF7    6YVH   
PDB (IMB)2HQ6    4R3E    5Z56    5Z58    6FF4    6FF7    6YVH   
Structural Biology KnowledgeBase2HQ6    4R3E    5Z56    5Z58    6FF4    6FF7    6YVH   
SCOP (Structural Classification of Proteins)2HQ6    4R3E    5Z56    5Z58    6FF4    6FF7    6YVH   
CATH (Classification of proteins structures)2HQ6    4R3E    5Z56    5Z58    6FF4    6FF7    6YVH   
SuperfamilyQ6UX04
AlphaFold pdb e-kbQ6UX04   
Human Protein Atlas [tissue]ENSG00000153015-CWC27 [tissue]
HPRD11541
Protein Interaction databases
DIP (DOE-UCLA)Q6UX04
IntAct (EBI)Q6UX04
BioGRIDCWC27
STRING (EMBL)CWC27
ZODIACCWC27
Ontologies - Pathways
QuickGOQ6UX04
Ontology : AmiGOmRNA splicing, via spliceosome  mRNA splicing, via spliceosome  protein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  nucleoplasm  nucleoplasm  protein folding  cyclosporin A binding  U2-type precatalytic spliceosome  catalytic step 2 spliceosome  
Ontology : EGO-EBImRNA splicing, via spliceosome  mRNA splicing, via spliceosome  protein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  nucleoplasm  nucleoplasm  protein folding  cyclosporin A binding  U2-type precatalytic spliceosome  catalytic step 2 spliceosome  
NDEx NetworkCWC27
Atlas of Cancer Signalling NetworkCWC27
Wikipedia pathwaysCWC27
Orthology - Evolution
OrthoDB10283
GeneTree (enSembl)ENSG00000153015
Phylogenetic Trees/Animal Genes : TreeFamCWC27
Homologs : HomoloGeneCWC27
Homology/Alignments : Family Browser (UCSC)CWC27
Gene fusions - Rearrangements
Fusion : MitelmanBDP1/CWC27 [5q13.2/5q12.3]  
Fusion : MitelmanCWC27/RNF180 [5q12.3/5q12.3]  
Fusion : QuiverCWC27
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCWC27 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CWC27
dbVarCWC27
ClinVarCWC27
MonarchCWC27
1000_GenomesCWC27 
Exome Variant ServerCWC27
GNOMAD BrowserENSG00000153015
Varsome BrowserCWC27
ACMGCWC27 variants
VarityQ6UX04
Genomic Variants (DGV)CWC27 [DGVbeta]
DECIPHERCWC27 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCWC27 
Mutations
ICGC Data PortalCWC27 
TCGA Data PortalCWC27 
Broad Tumor PortalCWC27
OASIS PortalCWC27 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCWC27  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCWC27
Mutations and Diseases : HGMDCWC27
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCWC27
DgiDB (Drug Gene Interaction Database)CWC27
DoCM (Curated mutations)CWC27
CIViC (Clinical Interpretations of Variants in Cancer)CWC27
Cancer3DCWC27
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM250410    617170   
Orphanet
DisGeNETCWC27
MedgenCWC27
Genetic Testing Registry CWC27
NextProtQ6UX04 [Medical]
GENETestsCWC27
Target ValidationCWC27
Huge Navigator CWC27 [HugePedia]
ClinGenCWC27
Clinical trials, drugs, therapy
MyCancerGenomeCWC27
Protein Interactions : CTDCWC27
Pharm GKB GenePA35594
PharosQ6UX04
Clinical trialCWC27
Miscellaneous
canSAR (ICR)CWC27
HarmonizomeCWC27
DataMed IndexCWC27
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCWC27
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:05:44 CEST 2021

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