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CWC27 (CWC27 spliceosome associated protein homolog)

Identity

Alias_namesSDCCAG10
serologically defined colon cancer antigen 10
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
CWC27 spliceosome-associated protein homolog
Alias_symbol (synonym)NY-CO-10
SDCCAG-10
Other alias
HGNC (Hugo) CWC27
LocusID (NCBI) 10283
Atlas_Id 42228
Location 5q12.3  [Link to chromosome band 5q12]
Location_base_pair Starts at 64768918 and ends at 65018763 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BDP1 (5q13.2) / CWC27 (5q12.3)CWC27 (5q12.3) / CWC27 (5q12.3)CWC27 (5q12.3) / RNF180 (5q12.3)
BDP1 5q13.2 / CWC27 5q12.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CWC27   10664
Cards
Entrez_Gene (NCBI)CWC27  10283  CWC27 spliceosome associated protein homolog
AliasesNY-CO-10; SDCCAG-10; SDCCAG10
GeneCards (Weizmann)CWC27
Ensembl hg19 (Hinxton)ENSG00000153015 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000153015 [Gene_View]  chr5:64768918-65018763 [Contig_View]  CWC27 [Vega]
ICGC DataPortalENSG00000153015
TCGA cBioPortalCWC27
AceView (NCBI)CWC27
Genatlas (Paris)CWC27
WikiGenes10283
SOURCE (Princeton)CWC27
Genetics Home Reference (NIH)CWC27
Genomic and cartography
GoldenPath hg38 (UCSC)CWC27  -     chr5:64768918-65018763 +  5q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CWC27  -     5q12.3   [Description]    (hg19-Feb_2009)
EnsemblCWC27 - 5q12.3 [CytoView hg19]  CWC27 - 5q12.3 [CytoView hg38]
Mapping of homologs : NCBICWC27 [Mapview hg19]  CWC27 [Mapview hg38]
OMIM617170   
Gene and transcription
Genbank (Entrez)AF039692 AF039693 AJ002573 AK225105 AK225161
RefSeq transcript (Entrez)NM_001297644 NM_001297645 NM_001318000 NM_005869
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CWC27
Cluster EST : UnigeneHs.371372 [ NCBI ]
CGAP (NCI)Hs.371372
Alternative Splicing GalleryENSG00000153015
Gene ExpressionCWC27 [ NCBI-GEO ]   CWC27 [ EBI - ARRAY_EXPRESS ]   CWC27 [ SEEK ]   CWC27 [ MEM ]
Gene Expression Viewer (FireBrowse)CWC27 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10283
GTEX Portal (Tissue expression)CWC27
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UX04   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UX04  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UX04
Splice isoforms : SwissVarQ6UX04
Catalytic activity : Enzyme5.2.1.8 [ Enzyme-Expasy ]   5.2.1.85.2.1.8 [ IntEnz-EBI ]   5.2.1.8 [ BRENDA ]   5.2.1.8 [ KEGG ]   
PhosPhoSitePlusQ6UX04
Domaine pattern : Prosite (Expaxy)CSA_PPIASE_1 (PS00170)    CSA_PPIASE_2 (PS50072)   
Domains : Interpro (EBI)Cyclophilin-like_dom    Cyclophilin-type_PPIase    Cyclophilin-type_PPIase_CS    Cyclophilin-type_PPIase_dom   
Domain families : Pfam (Sanger)Pro_isomerase (PF00160)   
Domain families : Pfam (NCBI)pfam00160   
Conserved Domain (NCBI)CWC27
DMDM Disease mutations10283
Blocks (Seattle)CWC27
PDB (SRS)2HQ6    4R3E   
PDB (PDBSum)2HQ6    4R3E   
PDB (IMB)2HQ6    4R3E   
PDB (RSDB)2HQ6    4R3E   
Structural Biology KnowledgeBase2HQ6    4R3E   
SCOP (Structural Classification of Proteins)2HQ6    4R3E   
CATH (Classification of proteins structures)2HQ6    4R3E   
SuperfamilyQ6UX04
Human Protein AtlasENSG00000153015
Peptide AtlasQ6UX04
HPRD11541
IPIIPI00025174   IPI00879475   IPI01018776   IPI00965668   
Protein Interaction databases
DIP (DOE-UCLA)Q6UX04
IntAct (EBI)Q6UX04
FunCoupENSG00000153015
BioGRIDCWC27
STRING (EMBL)CWC27
ZODIACCWC27
Ontologies - Pathways
QuickGOQ6UX04
Ontology : AmiGOmRNA splicing, via spliceosome  mRNA splicing, via spliceosome  protein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  nucleoplasm  protein folding  catalytic step 2 spliceosome  
Ontology : EGO-EBImRNA splicing, via spliceosome  mRNA splicing, via spliceosome  protein peptidyl-prolyl isomerization  peptidyl-prolyl cis-trans isomerase activity  nucleoplasm  protein folding  catalytic step 2 spliceosome  
NDEx NetworkCWC27
Atlas of Cancer Signalling NetworkCWC27
Wikipedia pathwaysCWC27
Orthology - Evolution
OrthoDB10283
GeneTree (enSembl)ENSG00000153015
Phylogenetic Trees/Animal Genes : TreeFamCWC27
HOVERGENQ6UX04
HOGENOMQ6UX04
Homologs : HomoloGeneCWC27
Homology/Alignments : Family Browser (UCSC)CWC27
Gene fusions - Rearrangements
Fusion : MitelmanBDP1/CWC27 [5q13.2/5q12.3]  [t(5;5)(q12;q13)]  
Fusion : MitelmanCWC27/RNF180 [5q12.3/5q12.3]  [t(5;5)(q12;q12)]  
Fusion: TCGABDP1 5q13.2 CWC27 5q12.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCWC27 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CWC27
dbVarCWC27
ClinVarCWC27
1000_GenomesCWC27 
Exome Variant ServerCWC27
ExAC (Exome Aggregation Consortium)CWC27 (select the gene name)
Genetic variants : HAPMAP10283
Genomic Variants (DGV)CWC27 [DGVbeta]
DECIPHERCWC27 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCWC27 
Mutations
ICGC Data PortalCWC27 
TCGA Data PortalCWC27 
Broad Tumor PortalCWC27
OASIS PortalCWC27 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCWC27  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCWC27
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CWC27
DgiDB (Drug Gene Interaction Database)CWC27
DoCM (Curated mutations)CWC27 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CWC27 (select a term)
intoGenCWC27
Cancer3DCWC27(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617170   
Orphanet
MedgenCWC27
Genetic Testing Registry CWC27
NextProtQ6UX04 [Medical]
TSGene10283
GENETestsCWC27
Target ValidationCWC27
Huge Navigator CWC27 [HugePedia]
snp3D : Map Gene to Disease10283
BioCentury BCIQCWC27
ClinGenCWC27
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10283
Chemical/Pharm GKB GenePA35594
Clinical trialCWC27
Miscellaneous
canSAR (ICR)CWC27 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCWC27
EVEXCWC27
GoPubMedCWC27
iHOPCWC27
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:30:10 CEST 2017

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