Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CXCL1 (chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha))

Identity

Other namesFSP
GRO1
GROa
MGSA
MGSA-a
NAP-3
SCYB1
HGNC (Hugo) CXCL1
LocusID (NCBI) 2919
Location 4q13.3
Location_base_pair Starts at 74735109 and ends at 74737019 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CXCL1   4602
Entrez_Gene (NCBI)CXCL1  2919  chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
Cards
GeneCards (Weizmann)CXCL1
Ensembl (Hinxton)ENSG00000163739 [Gene_View]  chr4:74735109-74737019 [Contig_View]  CXCL1 [Vega]
AceView (NCBI)CXCL1
Genatlas (Paris)CXCL1
SOURCE (Stanford)NM_001511
Genomic and cartography
GoldenPath (UCSC)CXCL1  -  4q13.3   chr4:74735109-74737019 +  4q13.3   [Description]    (hg19-Feb_2009)
EnsemblCXCL1 - 4q13.3 [CytoView]
Mapping of homologs : NCBICXCL1 [Mapview]
OMIM155730   
Gene and transcription
Genbank (Entrez)BC011976 BG121608 BM554448 BM996663 BQ000742
RefSeq transcript (SRS)NM_001511
RefSeq transcript (Entrez)NM_001511
RefSeq genomic (SRS)AC_000136 NC_000004 NC_018915 NT_022778 NW_001838914 NW_004078021
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_022778 NW_001838914 NW_004078021
Consensus coding sequences : CCDS (NCBI)CXCL1
Cluster EST : UnigeneHs.708652 [ SRS ] Hs.708652 [ NCBI ]
CGAP (NCI)Hs.708652
Alternative Splicing : Fast-db (Paris)GSHG0022658
Alternative Splicing GalleryENSG00000163739
Gene ExpressionCXCL1 [ NCBI-GEO ]   CXCL1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09341 (SRS) P09341 (Uniprot)
NextProtP09341
With graphics : InterProP09341
Splice isoforms : SwissVarP09341(Swissvar)
Domaine pattern : Prosite (SRS)SMALL_CYTOKINES_CXC (PS00471)   
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CXC (PS00471)   
Domains : Interpro (SRS)Chemokine_CXC    Chemokine_CXC_CS    Chemokine_CXCL8/IL8    Chemokine_IL8-like_dom   
Domains : Interpro (EBI)Chemokine_CXC    Chemokine_CXC_CS    Chemokine_CXCL8/IL8    Chemokine_IL8-like_dom   
Related proteins : CluSTrP09341
Domain families : Pfam (SRS)IL8 (PF00048)   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
DMDM2919
Blocks (Seattle)P09341
PDB (SRS)1MGS    1MSG    1MSH    1ROD   
PDB (PDBSum)1MGS    1MSG    1MSH    1ROD   
PDB (IMB)1MGS    1MSG    1MSH    1ROD   
PDB (RSDB)1MGS    1MSG    1MSH    1ROD   
Human Protein AtlasENSG00000163739
HPRD01119
IPIIPI00013874   
Protein Interaction databases
DIP (DOE-UCLA)P09341
IntAct (EBI)P09341
FunCoupENSG00000163739
REACTOMECXCL1
Protein Interaction Database2919
BioGRIDCXCL1
InParanoidP09341
Interologous Interaction database P09341
IntegromeDBCXCL1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CXCL1
SNP (GeneSNP Utah)CXCL1
SNP : HGBaseCXCL1
Genetic variants : HAPMAPCXCL1
Somatic Mutations in Cancer : COSMICCXCL1 
CONAN: Copy Number AnalysisCXCL1 
Mutations and Diseases : HGMDCXCL1
OMIM155730   
GENETests155730   
Disease Genetic AssociationCXCL1
Huge Navigator CXCL1 [HugePedia]  CXCL1 [HugeCancerGEM]
Genomic VariantsCXCL1  CXCL1 [DGVbeta]
snp3D : Map Gene to Disease2919
General knowledge
Homologs : HomoloGeneCXCL1
Homology/Alignments : Family Browser (UCSC)CXCL1
Phylogenetic Trees/Animal Genes : TreeFamCXCL1
Chemical/Protein Interactions : CTD2919
Chemical/Pharm GKB GenePA35050
Clinical trialCXCL1
Cancer Resource (Charite)ENSG00000163739
Ontology : AmiGOreceptor binding  extracellular region  extracellular space  intracellular  chemotaxis  inflammatory response  immune response  signal transduction  G-protein coupled receptor signaling pathway  nervous system development  chemokine activity  enzyme activator activity  growth factor activity  cell proliferation  negative regulation of cell proliferation  actin cytoskeleton organization  intracellular signal transduction  positive regulation of catalytic activity  
Ontology : EGO-EBIreceptor binding  extracellular region  extracellular space  intracellular  chemotaxis  inflammatory response  immune response  signal transduction  G-protein coupled receptor signaling pathway  nervous system development  chemokine activity  enzyme activator activity  growth factor activity  cell proliferation  negative regulation of cell proliferation  actin cytoskeleton organization  intracellular signal transduction  positive regulation of catalytic activity  
Pathways : KEGGCytokine-cytokine receptor interactionEpithelial cell signaling in Helicobacter pylori infection
Other databases
Probes
Litterature
PubMed121 Pubmed reference(s) in Entrez
PubGeneCXCL1
iHOPCXCL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:20:39 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.