Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CXCL3 (C-X-C motif chemokine ligand 3)

Identity

Other namesCINC-2b
GRO3
GROg
MIP-2b
MIP2B
SCYB3
HGNC (Hugo) CXCL3
LocusID (NCBI) 2921
Atlas_Id 40222
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 74902312 and ends at 74904490 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CXCL3   4604
Cards
Entrez_Gene (NCBI)CXCL3  2921  C-X-C motif chemokine ligand 3
AliasesCINC-2b; GRO3; GROg; MIP-2b; 
MIP2B; SCYB3
GeneCards (Weizmann)CXCL3
Ensembl hg19 (Hinxton)ENSG00000163734 [Gene_View]  chr4:74902312-74904490 [Contig_View]  CXCL3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000163734 [Gene_View]  chr4:74902312-74904490 [Contig_View]  CXCL3 [Vega]
ICGC DataPortalENSG00000163734
TCGA cBioPortalCXCL3
AceView (NCBI)CXCL3
Genatlas (Paris)CXCL3
WikiGenes2921
SOURCE (Princeton)CXCL3
Genomic and cartography
GoldenPath hg19 (UCSC)CXCL3  -     chr4:74902312-74904490 -  4q13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CXCL3  -     4q13.3   [Description]    (hg38-Dec_2013)
EnsemblCXCL3 - 4q13.3 [CytoView hg19]  CXCL3 - 4q13.3 [CytoView hg38]
Mapping of homologs : NCBICXCL3 [Mapview hg19]  CXCL3 [Mapview hg38]
OMIM139111   
Gene and transcription
Genbank (Entrez)AK307064 AK311367 AW079760 BC016308 BC065743
RefSeq transcript (Entrez)NM_002090
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)CXCL3
Cluster EST : UnigeneHs.89690 [ NCBI ]
CGAP (NCI)Hs.89690
Alternative Splicing GalleryENSG00000163734
Gene ExpressionCXCL3 [ NCBI-GEO ]   CXCL3 [ EBI - ARRAY_EXPRESS ]   CXCL3 [ SEEK ]   CXCL3 [ MEM ]
Gene Expression Viewer (FireBrowse)CXCL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2921
GTEX Portal (Tissue expression)CXCL3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP19876 (Uniprot)
NextProtP19876  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP19876
Splice isoforms : SwissVarP19876 (Swissvar)
PhosPhoSitePlusP19876
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CXC (PS00471)   
Domains : Interpro (EBI)Chemokine_CXC    Chemokine_CXC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
DMDM Disease mutations2921
Blocks (Seattle)CXCL3
SuperfamilyP19876
Human Protein AtlasENSG00000163734
Peptide AtlasP19876
HPRD00742
IPIIPI00218180   
Protein Interaction databases
DIP (DOE-UCLA)P19876
IntAct (EBI)P19876
FunCoupENSG00000163734
BioGRIDCXCL3
STRING (EMBL)CXCL3
ZODIACCXCL3
Ontologies - Pathways
QuickGOP19876
Ontology : AmiGOextracellular region  extracellular space  inflammatory response  immune response  G-protein coupled receptor signaling pathway  chemokine activity  chemokine activity  neutrophil chemotaxis  response to lipopolysaccharide  regulation of cell proliferation  CXCR chemokine receptor binding  chemokine-mediated signaling pathway  positive regulation of neutrophil chemotaxis  
Ontology : EGO-EBIextracellular region  extracellular space  inflammatory response  immune response  G-protein coupled receptor signaling pathway  chemokine activity  chemokine activity  neutrophil chemotaxis  response to lipopolysaccharide  regulation of cell proliferation  CXCR chemokine receptor binding  chemokine-mediated signaling pathway  positive regulation of neutrophil chemotaxis  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway    TNF signaling pathway    Salmonella infection    Legionellosis   
NDEx Network
Atlas of Cancer Signalling NetworkCXCL3
Wikipedia pathwaysCXCL3
Orthology - Evolution
OrthoDB2921
GeneTree (enSembl)ENSG00000163734
Phylogenetic Trees/Animal Genes : TreeFamCXCL3
Homologs : HomoloGeneCXCL3
Homology/Alignments : Family Browser (UCSC)CXCL3
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerCXCL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CXCL3
dbVarCXCL3
ClinVarCXCL3
1000_GenomesCXCL3 
Exome Variant ServerCXCL3
ExAC (Exome Aggregation Consortium)CXCL3 (select the gene name)
Genetic variants : HAPMAP2921
Genomic Variants (DGV)CXCL3 [DGVbeta]
Mutations
ICGC Data PortalCXCL3 
TCGA Data PortalCXCL3 
Broad Tumor PortalCXCL3
OASIS PortalCXCL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCXCL3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CXCL3
DgiDB (Drug Gene Interaction Database)CXCL3
DoCM (Curated mutations)CXCL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CXCL3 (select a term)
intoGenCXCL3
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)4:74902312-74904490  ENSG00000163734
CONAN: Copy Number AnalysisCXCL3 
Mutations and Diseases : HGMDCXCL3
OMIM139111   
MedgenCXCL3
Genetic Testing Registry CXCL3
NextProtP19876 [Medical]
TSGene2921
GENETestsCXCL3
Huge Navigator CXCL3 [HugePedia]
snp3D : Map Gene to Disease2921
BioCentury BCIQCXCL3
ClinGenCXCL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2921
Chemical/Pharm GKB GenePA35052
Clinical trialCXCL3
Miscellaneous
canSAR (ICR)CXCL3 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCXCL3
EVEXCXCL3
GoPubMedCXCL3
iHOPCXCL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 9 19:03:28 CEST 2016

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