Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CXCL9 (C-X-C motif chemokine ligand 9)

Identity

Alias_namesCMK
MIG
monokine induced by gamma interferon
chemokine (C-X-C motif) ligand 9
Alias_symbol (synonym)SCYB9
Humig
crg-10
Other alias
HGNC (Hugo) CXCL9
LocusID (NCBI) 4283
Atlas_Id 43945
Location 4q21.1  [Link to chromosome band 4q21]
Location_base_pair Starts at 76922495 and ends at 76928676 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CXCL9 (4q21.1) / CARD6 (5p13.1)SOD1 (21q22.11) / CXCL9 (4q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CXCL9   7098
Cards
Entrez_Gene (NCBI)CXCL9  4283  C-X-C motif chemokine ligand 9
AliasesCMK; Humig; MIG; SCYB9; 
crg-10
GeneCards (Weizmann)CXCL9
Ensembl hg19 (Hinxton)ENSG00000138755 [Gene_View]  chr4:76922495-76928676 [Contig_View]  CXCL9 [Vega]
Ensembl hg38 (Hinxton)ENSG00000138755 [Gene_View]  chr4:76922495-76928676 [Contig_View]  CXCL9 [Vega]
ICGC DataPortalENSG00000138755
TCGA cBioPortalCXCL9
AceView (NCBI)CXCL9
Genatlas (Paris)CXCL9
WikiGenes4283
SOURCE (Princeton)CXCL9
Genetics Home Reference (NIH)CXCL9
Genomic and cartography
GoldenPath hg19 (UCSC)CXCL9  -     chr4:76922495-76928676 -  4q21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CXCL9  -     4q21.1   [Description]    (hg38-Dec_2013)
EnsemblCXCL9 - 4q21.1 [CytoView hg19]  CXCL9 - 4q21.1 [CytoView hg38]
Mapping of homologs : NCBICXCL9 [Mapview hg19]  CXCL9 [Mapview hg38]
OMIM601704   
Gene and transcription
Genbank (Entrez)AK311852 BC025745 BC042178 BC063122 BC095396
RefSeq transcript (Entrez)NM_002416
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)CXCL9
Cluster EST : UnigeneHs.77367 [ NCBI ]
CGAP (NCI)Hs.77367
Alternative Splicing GalleryENSG00000138755
Gene ExpressionCXCL9 [ NCBI-GEO ]   CXCL9 [ EBI - ARRAY_EXPRESS ]   CXCL9 [ SEEK ]   CXCL9 [ MEM ]
Gene Expression Viewer (FireBrowse)CXCL9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4283
GTEX Portal (Tissue expression)CXCL9
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ07325   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ07325  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ07325
Splice isoforms : SwissVarQ07325
PhosPhoSitePlusQ07325
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CXC (PS00471)   
Domains : Interpro (EBI)Chemokine_CXC    Chemokine_CXC_CS    Chemokine_IL8-like_dom    CXCL9   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CXCL9
DMDM Disease mutations4283
Blocks (Seattle)CXCL9
SuperfamilyQ07325
Human Protein AtlasENSG00000138755
Peptide AtlasQ07325
HPRD03416
IPIIPI00016534   
Protein Interaction databases
DIP (DOE-UCLA)Q07325
IntAct (EBI)Q07325
FunCoupENSG00000138755
BioGRIDCXCL9
STRING (EMBL)CXCL9
ZODIACCXCL9
Ontologies - Pathways
QuickGOQ07325
Ontology : AmiGOpositive regulation of leukocyte chemotaxis  cytokine activity  protein binding  extracellular region  extracellular space  chemotaxis  defense response  inflammatory response  immune response  cellular defense response  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  external side of plasma membrane  positive regulation of cAMP metabolic process  response to lipopolysaccharide  regulation of cell proliferation  positive regulation of cAMP-mediated signaling  positive regulation of myoblast differentiation  CXCR3 chemokine receptor binding  positive regulation of release of sequestered calcium ion into cytosol  defense response to virus  cell chemotaxis  cell chemotaxis  cell chemotaxis  chemokine-mediated signaling pathway  positive regulation of myoblast fusion  
Ontology : EGO-EBIpositive regulation of leukocyte chemotaxis  cytokine activity  protein binding  extracellular region  extracellular space  chemotaxis  defense response  inflammatory response  immune response  cellular defense response  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  external side of plasma membrane  positive regulation of cAMP metabolic process  response to lipopolysaccharide  regulation of cell proliferation  positive regulation of cAMP-mediated signaling  positive regulation of myoblast differentiation  CXCR3 chemokine receptor binding  positive regulation of release of sequestered calcium ion into cytosol  defense response to virus  cell chemotaxis  cell chemotaxis  cell chemotaxis  chemokine-mediated signaling pathway  positive regulation of myoblast fusion  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway    Toll-like receptor signaling pathway   
NDEx NetworkCXCL9
Atlas of Cancer Signalling NetworkCXCL9
Wikipedia pathwaysCXCL9
Orthology - Evolution
OrthoDB4283
GeneTree (enSembl)ENSG00000138755
Phylogenetic Trees/Animal Genes : TreeFamCXCL9
HOVERGENQ07325
HOGENOMQ07325
Homologs : HomoloGeneCXCL9
Homology/Alignments : Family Browser (UCSC)CXCL9
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCXCL9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CXCL9
dbVarCXCL9
ClinVarCXCL9
1000_GenomesCXCL9 
Exome Variant ServerCXCL9
ExAC (Exome Aggregation Consortium)CXCL9 (select the gene name)
Genetic variants : HAPMAP4283
Genomic Variants (DGV)CXCL9 [DGVbeta]
DECIPHER (Syndromes)4:76922495-76928676  ENSG00000138755
CONAN: Copy Number AnalysisCXCL9 
Mutations
ICGC Data PortalCXCL9 
TCGA Data PortalCXCL9 
Broad Tumor PortalCXCL9
OASIS PortalCXCL9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCXCL9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCXCL9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CXCL9
DgiDB (Drug Gene Interaction Database)CXCL9
DoCM (Curated mutations)CXCL9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CXCL9 (select a term)
intoGenCXCL9
Cancer3DCXCL9(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601704   
Orphanet
MedgenCXCL9
Genetic Testing Registry CXCL9
NextProtQ07325 [Medical]
TSGene4283
GENETestsCXCL9
Huge Navigator CXCL9 [HugePedia]
snp3D : Map Gene to Disease4283
BioCentury BCIQCXCL9
ClinGenCXCL9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4283
Chemical/Pharm GKB GenePA35495
Clinical trialCXCL9
Miscellaneous
canSAR (ICR)CXCL9 (select the gene name)
Probes
Litterature
PubMed144 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCXCL9
EVEXCXCL9
GoPubMedCXCL9
iHOPCXCL9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:02:20 CET 2017

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