Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CXCR6 (C-X-C motif chemokine receptor 6)

Identity

Alias_nameschemokine (C-X-C motif) receptor 6
Alias_symbol (synonym)TYMSTR
STRL33
BONZO
CD186
Other alias
HGNC (Hugo) CXCR6
LocusID (NCBI) 10663
Atlas_Id 46390
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 45943481 and ends at 45948353 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CXCR6   16647
Cards
Entrez_Gene (NCBI)CXCR6  10663  C-X-C motif chemokine receptor 6
AliasesBONZO; CD186; STRL33; TYMSTR
GeneCards (Weizmann)CXCR6
Ensembl hg19 (Hinxton)ENSG00000172215 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172215 [Gene_View]  chr3:45943481-45948353 [Contig_View]  CXCR6 [Vega]
ICGC DataPortalENSG00000172215
TCGA cBioPortalCXCR6
AceView (NCBI)CXCR6
Genatlas (Paris)CXCR6
WikiGenes10663
SOURCE (Princeton)CXCR6
Genetics Home Reference (NIH)CXCR6
Genomic and cartography
GoldenPath hg38 (UCSC)CXCR6  -     chr3:45943481-45948353 +  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CXCR6  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblCXCR6 - 3p21.31 [CytoView hg19]  CXCR6 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBICXCR6 [Mapview hg19]  CXCR6 [Mapview hg38]
OMIM605163   
Gene and transcription
Genbank (Entrez)AF007545 AK313754 BC033584 DQ892101 DQ895294
RefSeq transcript (Entrez)NM_006564
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CXCR6
Cluster EST : UnigeneHs.737579 [ NCBI ]
CGAP (NCI)Hs.737579
Alternative Splicing GalleryENSG00000172215
Gene ExpressionCXCR6 [ NCBI-GEO ]   CXCR6 [ EBI - ARRAY_EXPRESS ]   CXCR6 [ SEEK ]   CXCR6 [ MEM ]
Gene Expression Viewer (FireBrowse)CXCR6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10663
GTEX Portal (Tissue expression)CXCR6
Human Protein AtlasENSG00000172215-CXCR6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00574   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00574  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00574
Splice isoforms : SwissVarO00574
PhosPhoSitePlusO00574
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Chemokine_CXCR6    Chemokine_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)CXCR6
DMDM Disease mutations10663
Blocks (Seattle)CXCR6
SuperfamilyO00574
Human Protein Atlas [tissue]ENSG00000172215-CXCR6 [tissue]
Peptide AtlasO00574
HPRD05520
IPIIPI00012166   
Protein Interaction databases
DIP (DOE-UCLA)O00574
IntAct (EBI)O00574
FunCoupENSG00000172215
BioGRIDCXCR6
STRING (EMBL)CXCR6
ZODIACCXCR6
Ontologies - Pathways
QuickGOO00574
Ontology : AmiGOG-protein coupled receptor activity  plasma membrane  integral component of plasma membrane  chemotaxis  inflammatory response  G-protein coupled receptor signaling pathway  coreceptor activity  C-X-C chemokine receptor activity  viral genome replication  C-X-C chemokine binding  chemokine-mediated signaling pathway  
Ontology : EGO-EBIG-protein coupled receptor activity  plasma membrane  integral component of plasma membrane  chemotaxis  inflammatory response  G-protein coupled receptor signaling pathway  coreceptor activity  C-X-C chemokine receptor activity  viral genome replication  C-X-C chemokine binding  chemokine-mediated signaling pathway  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkCXCR6
Atlas of Cancer Signalling NetworkCXCR6
Wikipedia pathwaysCXCR6
Orthology - Evolution
OrthoDB10663
GeneTree (enSembl)ENSG00000172215
Phylogenetic Trees/Animal Genes : TreeFamCXCR6
HOVERGENO00574
HOGENOMO00574
Homologs : HomoloGeneCXCR6
Homology/Alignments : Family Browser (UCSC)CXCR6
Gene fusions - Rearrangements
Tumor Fusion PortalCXCR6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCXCR6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CXCR6
dbVarCXCR6
ClinVarCXCR6
1000_GenomesCXCR6 
Exome Variant ServerCXCR6
ExAC (Exome Aggregation Consortium)ENSG00000172215
GNOMAD BrowserENSG00000172215
Genetic variants : HAPMAP10663
Genomic Variants (DGV)CXCR6 [DGVbeta]
DECIPHERCXCR6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCXCR6 
Mutations
ICGC Data PortalCXCR6 
TCGA Data PortalCXCR6 
Broad Tumor PortalCXCR6
OASIS PortalCXCR6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCXCR6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCXCR6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CXCR6
DgiDB (Drug Gene Interaction Database)CXCR6
DoCM (Curated mutations)CXCR6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CXCR6 (select a term)
intoGenCXCR6
Cancer3DCXCR6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605163   
Orphanet
DisGeNETCXCR6
MedgenCXCR6
Genetic Testing Registry CXCR6
NextProtO00574 [Medical]
TSGene10663
GENETestsCXCR6
Target ValidationCXCR6
Huge Navigator CXCR6 [HugePedia]
snp3D : Map Gene to Disease10663
BioCentury BCIQCXCR6
ClinGenCXCR6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10663
Chemical/Pharm GKB GenePA38409
Clinical trialCXCR6
Miscellaneous
canSAR (ICR)CXCR6 (select the gene name)
Probes
Litterature
PubMed72 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCXCR6
EVEXCXCR6
GoPubMedCXCR6
iHOPCXCR6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:09:38 CET 2017

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