Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CXXC1 (CXXC finger protein 1)

Identity

Alias_namesCXXC finger 1 (PHD domain)
Alias_symbol (synonym)HsT2645
PCCX1
hCGBP
PHF18
CGBP
SPP1
CFP1
ZCGPC1
Other alias2410002I16Rik
5830420C16Rik
HGNC (Hugo) CXXC1
LocusID (NCBI) 30827
Atlas_Id 56040
Location 18q21.1  [Link to chromosome band 18q21]
Location_base_pair Starts at 50282343 and ends at 50288322 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CXXC1 (18q21.1) / MYO5B (18q21.1)MRS2 (6p22.3) / CXXC1 (18q21.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CXXC1   24343
Cards
Entrez_Gene (NCBI)CXXC1  30827  CXXC finger protein 1
Aliases2410002I16Rik; 5830420C16Rik; CFP1; CGBP; 
HsT2645; PCCX1; PHF18; SPP1; ZCGPC1; hCGBP
GeneCards (Weizmann)CXXC1
Ensembl hg19 (Hinxton)ENSG00000154832 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000154832 [Gene_View]  chr18:50282343-50288322 [Contig_View]  CXXC1 [Vega]
ICGC DataPortalENSG00000154832
TCGA cBioPortalCXXC1
AceView (NCBI)CXXC1
Genatlas (Paris)CXXC1
WikiGenes30827
SOURCE (Princeton)CXXC1
Genetics Home Reference (NIH)CXXC1
Genomic and cartography
GoldenPath hg38 (UCSC)CXXC1  -     chr18:50282343-50288322 -  18q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CXXC1  -     18q21.1   [Description]    (hg19-Feb_2009)
EnsemblCXXC1 - 18q21.1 [CytoView hg19]  CXXC1 - 18q21.1 [CytoView hg38]
Mapping of homologs : NCBICXXC1 [Mapview hg19]  CXXC1 [Mapview hg38]
OMIM609150   
Gene and transcription
Genbank (Entrez)AA236925 AB031069 AB209883 AF149758 AK294645
RefSeq transcript (Entrez)NM_001101654 NM_014593
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CXXC1
Cluster EST : UnigeneHs.180933 [ NCBI ]
CGAP (NCI)Hs.180933
Alternative Splicing GalleryENSG00000154832
Gene ExpressionCXXC1 [ NCBI-GEO ]   CXXC1 [ EBI - ARRAY_EXPRESS ]   CXXC1 [ SEEK ]   CXXC1 [ MEM ]
Gene Expression Viewer (FireBrowse)CXXC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)30827
GTEX Portal (Tissue expression)CXXC1
Human Protein AtlasENSG00000154832-CXXC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P0U4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P0U4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P0U4
Splice isoforms : SwissVarQ9P0U4
PhosPhoSitePlusQ9P0U4
Domaine pattern : Prosite (Expaxy)ZF_CXXC (PS51058)    ZF_PHD_1 (PS01359)    ZF_PHD_2 (PS50016)   
Domains : Interpro (EBI)CpG-bd_C    Zinc_finger_PHD-type_CS    Znf_CXXC    Znf_FYVE_PHD    Znf_PHD    Znf_PHD-finger    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)PHD (PF00628)    zf-CpG_bind_C (PF12269)    zf-CXXC (PF02008)   
Domain families : Pfam (NCBI)pfam00628    pfam12269    pfam02008   
Domain families : Smart (EMBL)PHD (SM00249)  
Conserved Domain (NCBI)CXXC1
DMDM Disease mutations30827
Blocks (Seattle)CXXC1
PDB (SRS)3QMB    3QMC    3QMD    3QMG    3QMH    3QMI   
PDB (PDBSum)3QMB    3QMC    3QMD    3QMG    3QMH    3QMI   
PDB (IMB)3QMB    3QMC    3QMD    3QMG    3QMH    3QMI   
PDB (RSDB)3QMB    3QMC    3QMD    3QMG    3QMH    3QMI   
Structural Biology KnowledgeBase3QMB    3QMC    3QMD    3QMG    3QMH    3QMI   
SCOP (Structural Classification of Proteins)3QMB    3QMC    3QMD    3QMG    3QMH    3QMI   
CATH (Classification of proteins structures)3QMB    3QMC    3QMD    3QMG    3QMH    3QMI   
SuperfamilyQ9P0U4
Human Protein Atlas [tissue]ENSG00000154832-CXXC1 [tissue]
Peptide AtlasQ9P0U4
HPRD10852
IPIIPI00292445   IPI00641026   IPI00640766   
Protein Interaction databases
DIP (DOE-UCLA)Q9P0U4
IntAct (EBI)Q9P0U4
FunCoupENSG00000154832
BioGRIDCXXC1
STRING (EMBL)CXXC1
ZODIACCXXC1
Ontologies - Pathways
QuickGOQ9P0U4
Ontology : AmiGOcore promoter proximal region sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  zinc ion binding  nuclear matrix  nuclear speck  histone methyltransferase complex  IRE1-mediated unfolded protein response  histone methyltransferase activity (H3-K4 specific)  unmethylated CpG binding  positive regulation of transcription, DNA-templated  Set1C/COMPASS complex  histone H3-K4 methylation  
Ontology : EGO-EBIcore promoter proximal region sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  zinc ion binding  nuclear matrix  nuclear speck  histone methyltransferase complex  IRE1-mediated unfolded protein response  histone methyltransferase activity (H3-K4 specific)  unmethylated CpG binding  positive regulation of transcription, DNA-templated  Set1C/COMPASS complex  histone H3-K4 methylation  
NDEx NetworkCXXC1
Atlas of Cancer Signalling NetworkCXXC1
Wikipedia pathwaysCXXC1
Orthology - Evolution
OrthoDB30827
GeneTree (enSembl)ENSG00000154832
Phylogenetic Trees/Animal Genes : TreeFamCXXC1
HOVERGENQ9P0U4
HOGENOMQ9P0U4
Homologs : HomoloGeneCXXC1
Homology/Alignments : Family Browser (UCSC)CXXC1
Gene fusions - Rearrangements
Tumor Fusion PortalCXXC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCXXC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CXXC1
dbVarCXXC1
ClinVarCXXC1
1000_GenomesCXXC1 
Exome Variant ServerCXXC1
ExAC (Exome Aggregation Consortium)ENSG00000154832
GNOMAD BrowserENSG00000154832
Genetic variants : HAPMAP30827
Genomic Variants (DGV)CXXC1 [DGVbeta]
DECIPHERCXXC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCXXC1 
Mutations
ICGC Data PortalCXXC1 
TCGA Data PortalCXXC1 
Broad Tumor PortalCXXC1
OASIS PortalCXXC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCXXC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCXXC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CXXC1
DgiDB (Drug Gene Interaction Database)CXXC1
DoCM (Curated mutations)CXXC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CXXC1 (select a term)
intoGenCXXC1
Cancer3DCXXC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609150   
Orphanet
DisGeNETCXXC1
MedgenCXXC1
Genetic Testing Registry CXXC1
NextProtQ9P0U4 [Medical]
TSGene30827
GENETestsCXXC1
Target ValidationCXXC1
Huge Navigator CXXC1 [HugePedia]
snp3D : Map Gene to Disease30827
BioCentury BCIQCXXC1
ClinGenCXXC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD30827
Chemical/Pharm GKB GenePA134908762
Clinical trialCXXC1
Miscellaneous
canSAR (ICR)CXXC1 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCXXC1
EVEXCXXC1
GoPubMedCXXC1
iHOPCXXC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:09:39 CET 2017

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