Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYB5B (cytochrome b5 type B)

Identity

Alias_namescytochrome b5 type B (outer mitochondrial membrane)
Alias_symbol (synonym)CYB5-M
Other aliasCYPB5M
OMB5
HGNC (Hugo) CYB5B
LocusID (NCBI) 80777
Atlas_Id 51507
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 69424595 and ends at 69466264 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CYB5B (16q22.1) / ALAS2 (Xp11.21)CYB5B (16q22.1) / CALB2 (16q22.2)CYB5B (16q22.1) / CYB5B (16q22.1)
CYB5B (16q22.1) / PMFBP1 (16q22.2)CYB5B (16q22.1) / UTP4 (16q22.1)NUP93 (16q13) / CYB5B (16q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYB5B   24374
Cards
Entrez_Gene (NCBI)CYB5B  80777  cytochrome b5 type B
AliasesCYB5-M; CYPB5M; OMB5
GeneCards (Weizmann)CYB5B
Ensembl hg19 (Hinxton)ENSG00000103018 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103018 [Gene_View]  chr16:69424595-69466264 [Contig_View]  CYB5B [Vega]
ICGC DataPortalENSG00000103018
TCGA cBioPortalCYB5B
AceView (NCBI)CYB5B
Genatlas (Paris)CYB5B
WikiGenes80777
SOURCE (Princeton)CYB5B
Genetics Home Reference (NIH)CYB5B
Genomic and cartography
GoldenPath hg38 (UCSC)CYB5B  -     chr16:69424595-69466264 +  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYB5B  -     16q22.1   [Description]    (hg19-Feb_2009)
EnsemblCYB5B - 16q22.1 [CytoView hg19]  CYB5B - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBICYB5B [Mapview hg19]  CYB5B [Mapview hg38]
OMIM611964   
Gene and transcription
Genbank (Entrez)AB009282 AK098148 AK125218 AK291576 BC004373
RefSeq transcript (Entrez)NM_030579
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYB5B
Cluster EST : UnigeneHs.461131 [ NCBI ]
CGAP (NCI)Hs.461131
Alternative Splicing GalleryENSG00000103018
Gene ExpressionCYB5B [ NCBI-GEO ]   CYB5B [ EBI - ARRAY_EXPRESS ]   CYB5B [ SEEK ]   CYB5B [ MEM ]
Gene Expression Viewer (FireBrowse)CYB5B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80777
GTEX Portal (Tissue expression)CYB5B
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43169   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43169  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43169
Splice isoforms : SwissVarO43169
PhosPhoSitePlusO43169
Domaine pattern : Prosite (Expaxy)CYTOCHROME_B5_1 (PS00191)    CYTOCHROME_B5_2 (PS50255)   
Domains : Interpro (EBI)Aquaporin-like    Cyt_B5-like_heme/steroid-bd    Cyt_B5_heme-BS   
Domain families : Pfam (Sanger)Cyt-b5 (PF00173)   
Domain families : Pfam (NCBI)pfam00173   
Domain families : Smart (EMBL)Cyt-b5 (SM01117)  
Conserved Domain (NCBI)CYB5B
DMDM Disease mutations80777
Blocks (Seattle)CYB5B
PDB (SRS)3NER   
PDB (PDBSum)3NER   
PDB (IMB)3NER   
PDB (RSDB)3NER   
Structural Biology KnowledgeBase3NER   
SCOP (Structural Classification of Proteins)3NER   
CATH (Classification of proteins structures)3NER   
SuperfamilyO43169
Human Protein AtlasENSG00000103018
Peptide AtlasO43169
HPRD13106
IPIIPI00303954   IPI00966243   
Protein Interaction databases
DIP (DOE-UCLA)O43169
IntAct (EBI)O43169
FunCoupENSG00000103018
BioGRIDCYB5B
STRING (EMBL)CYB5B
ZODIACCYB5B
Ontologies - Pathways
QuickGOO43169
Ontology : AmiGOprotein binding  mitochondrial outer membrane  xenobiotic metabolic process  membrane  integral component of membrane  heme binding  metal ion binding  oxidation-reduction process  
Ontology : EGO-EBIprotein binding  mitochondrial outer membrane  xenobiotic metabolic process  membrane  integral component of membrane  heme binding  metal ion binding  oxidation-reduction process  
NDEx NetworkCYB5B
Atlas of Cancer Signalling NetworkCYB5B
Wikipedia pathwaysCYB5B
Orthology - Evolution
OrthoDB80777
GeneTree (enSembl)ENSG00000103018
Phylogenetic Trees/Animal Genes : TreeFamCYB5B
HOVERGENO43169
HOGENOMO43169
Homologs : HomoloGeneCYB5B
Homology/Alignments : Family Browser (UCSC)CYB5B
Gene fusions - Rearrangements
Fusion : MitelmanCYB5B/CALB2 [16q22.1/16q22.2]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYB5B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYB5B
dbVarCYB5B
ClinVarCYB5B
1000_GenomesCYB5B 
Exome Variant ServerCYB5B
ExAC (Exome Aggregation Consortium)CYB5B (select the gene name)
Genetic variants : HAPMAP80777
Genomic Variants (DGV)CYB5B [DGVbeta]
DECIPHERCYB5B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYB5B 
Mutations
ICGC Data PortalCYB5B 
TCGA Data PortalCYB5B 
Broad Tumor PortalCYB5B
OASIS PortalCYB5B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYB5B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYB5B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch CYB5B
DgiDB (Drug Gene Interaction Database)CYB5B
DoCM (Curated mutations)CYB5B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYB5B (select a term)
intoGenCYB5B
Cancer3DCYB5B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611964   
Orphanet
MedgenCYB5B
Genetic Testing Registry CYB5B
NextProtO43169 [Medical]
TSGene80777
GENETestsCYB5B
Huge Navigator CYB5B [HugePedia]
snp3D : Map Gene to Disease80777
BioCentury BCIQCYB5B
ClinGenCYB5B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80777
Chemical/Pharm GKB GenePA143485445
Clinical trialCYB5B
Miscellaneous
canSAR (ICR)CYB5B (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYB5B
EVEXCYB5B
GoPubMedCYB5B
iHOPCYB5B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:12:26 CEST 2017

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