Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYC1 (cytochrome c1)

Identity

Alias_symbol (synonym)UQCR4
Other aliasMC3DN6
HGNC (Hugo) CYC1
LocusID (NCBI) 1537
Atlas_Id 43222
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 145149938 and ends at 145152430 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CYC1 (8q24.3) / C1QB (1p36.12)CYC1 (8q24.3) / TRBV20-1 ()MIS18A (21q22.11) / CYC1 (8q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYC1   2579
Cards
Entrez_Gene (NCBI)CYC1  1537  cytochrome c1
AliasesMC3DN6; UQCR4
GeneCards (Weizmann)CYC1
Ensembl hg19 (Hinxton)ENSG00000179091 [Gene_View]  chr8:145149938-145152430 [Contig_View]  CYC1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000179091 [Gene_View]  chr8:145149938-145152430 [Contig_View]  CYC1 [Vega]
ICGC DataPortalENSG00000179091
TCGA cBioPortalCYC1
AceView (NCBI)CYC1
Genatlas (Paris)CYC1
WikiGenes1537
SOURCE (Princeton)CYC1
Genetics Home Reference (NIH)CYC1
Genomic and cartography
GoldenPath hg19 (UCSC)CYC1  -     chr8:145149938-145152430 +  8q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CYC1  -     8q24.3   [Description]    (hg38-Dec_2013)
EnsemblCYC1 - 8q24.3 [CytoView hg19]  CYC1 - 8q24.3 [CytoView hg38]
Mapping of homologs : NCBICYC1 [Mapview hg19]  CYC1 [Mapview hg38]
OMIM123980   615453   
Gene and transcription
Genbank (Entrez)AK026633 AK225796 BC001006 BC015616 BC020566
RefSeq transcript (Entrez)NM_001916
RefSeq genomic (Entrez)NC_000008 NC_018919 NG_033872 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)CYC1
Cluster EST : UnigeneHs.289271 [ NCBI ]
CGAP (NCI)Hs.289271
Alternative Splicing GalleryENSG00000179091
Gene ExpressionCYC1 [ NCBI-GEO ]   CYC1 [ EBI - ARRAY_EXPRESS ]   CYC1 [ SEEK ]   CYC1 [ MEM ]
Gene Expression Viewer (FireBrowse)CYC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1537
GTEX Portal (Tissue expression)CYC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08574   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08574  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08574
Splice isoforms : SwissVarP08574
PhosPhoSitePlusP08574
Domains : Interpro (EBI)Cyt_c-like_dom    Cyt_c1    Cyt_c1_TM_anchor_C   
Domain families : Pfam (Sanger)Cytochrom_C1 (PF02167)   
Domain families : Pfam (NCBI)pfam02167   
Conserved Domain (NCBI)CYC1
DMDM Disease mutations1537
Blocks (Seattle)CYC1
SuperfamilyP08574
Human Protein AtlasENSG00000179091
Peptide AtlasP08574
HPRD00480
IPIIPI00029264   
Protein Interaction databases
DIP (DOE-UCLA)P08574
IntAct (EBI)P08574
FunCoupENSG00000179091
BioGRIDCYC1
STRING (EMBL)CYC1
ZODIACCYC1
Ontologies - Pathways
QuickGOP08574
Ontology : AmiGOnucleus  mitochondrion  mitochondrial inner membrane  mitochondrial electron transport, ubiquinol to cytochrome c  membrane  integral component of membrane  heme binding  response to glucagon  electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity  metal ion binding  respiratory chain  
Ontology : EGO-EBInucleus  mitochondrion  mitochondrial inner membrane  mitochondrial electron transport, ubiquinol to cytochrome c  membrane  integral component of membrane  heme binding  response to glucagon  electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity  metal ion binding  respiratory chain  
Pathways : KEGGOxidative phosphorylation    Cardiac muscle contraction    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkCYC1
Atlas of Cancer Signalling NetworkCYC1
Wikipedia pathwaysCYC1
Orthology - Evolution
OrthoDB1537
GeneTree (enSembl)ENSG00000179091
Phylogenetic Trees/Animal Genes : TreeFamCYC1
HOVERGENP08574
HOGENOMP08574
Homologs : HomoloGeneCYC1
Homology/Alignments : Family Browser (UCSC)CYC1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYC1
dbVarCYC1
ClinVarCYC1
1000_GenomesCYC1 
Exome Variant ServerCYC1
ExAC (Exome Aggregation Consortium)CYC1 (select the gene name)
Genetic variants : HAPMAP1537
Genomic Variants (DGV)CYC1 [DGVbeta]
DECIPHER (Syndromes)8:145149938-145152430  ENSG00000179091
CONAN: Copy Number AnalysisCYC1 
Mutations
ICGC Data PortalCYC1 
TCGA Data PortalCYC1 
Broad Tumor PortalCYC1
OASIS PortalCYC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch CYC1
DgiDB (Drug Gene Interaction Database)CYC1
DoCM (Curated mutations)CYC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYC1 (select a term)
intoGenCYC1
Cancer3DCYC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM123980    615453   
Orphanet3378   
MedgenCYC1
Genetic Testing Registry CYC1
NextProtP08574 [Medical]
TSGene1537
GENETestsCYC1
Huge Navigator CYC1 [HugePedia]
snp3D : Map Gene to Disease1537
BioCentury BCIQCYC1
ClinGenCYC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1537
Chemical/Pharm GKB GenePA27077
Clinical trialCYC1
Miscellaneous
canSAR (ICR)CYC1 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYC1
EVEXCYC1
GoPubMedCYC1
iHOPCYC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:58:11 CEST 2017

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