Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYGB (cytoglobin)

Identity

Alias_symbol (synonym)HGB
STAP
Other alias
HGNC (Hugo) CYGB
LocusID (NCBI) 114757
Atlas_Id 46125
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 74523430 and ends at 74533987 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PTPRD (9p24.1) / CYGB (17q25.1)PTPRD 9p24.1 / CYGB 17q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYGB   16505
Cards
Entrez_Gene (NCBI)CYGB  114757  cytoglobin
AliasesHGB; STAP
GeneCards (Weizmann)CYGB
Ensembl hg19 (Hinxton)ENSG00000161544 [Gene_View]  chr17:74523430-74533987 [Contig_View]  CYGB [Vega]
Ensembl hg38 (Hinxton)ENSG00000161544 [Gene_View]  chr17:74523430-74533987 [Contig_View]  CYGB [Vega]
ICGC DataPortalENSG00000161544
TCGA cBioPortalCYGB
AceView (NCBI)CYGB
Genatlas (Paris)CYGB
WikiGenes114757
SOURCE (Princeton)CYGB
Genetics Home Reference (NIH)CYGB
Genomic and cartography
GoldenPath hg19 (UCSC)CYGB  -     chr17:74523430-74533987 -  17q25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CYGB  -     17q25.1   [Description]    (hg38-Dec_2013)
EnsemblCYGB - 17q25.1 [CytoView hg19]  CYGB - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBICYGB [Mapview hg19]  CYGB [Mapview hg38]
OMIM608759   
Gene and transcription
Genbank (Entrez)AB057769 AI470692 AJ315162 AK098057 BC029798
RefSeq transcript (Entrez)NM_134268
RefSeq genomic (Entrez)NC_000017 NC_018928 NG_016702 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)CYGB
Cluster EST : UnigeneHs.95120 [ NCBI ]
CGAP (NCI)Hs.95120
Alternative Splicing GalleryENSG00000161544
Gene ExpressionCYGB [ NCBI-GEO ]   CYGB [ EBI - ARRAY_EXPRESS ]   CYGB [ SEEK ]   CYGB [ MEM ]
Gene Expression Viewer (FireBrowse)CYGB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)114757
GTEX Portal (Tissue expression)CYGB
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WWM9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WWM9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WWM9
Splice isoforms : SwissVarQ8WWM9
PhosPhoSitePlusQ8WWM9
Domaine pattern : Prosite (Expaxy)GLOBIN (PS01033)   
Domains : Interpro (EBI)Globin    Globin-like    Globin/Proto    Globin_lamprey/hagfish   
Domain families : Pfam (Sanger)Globin (PF00042)   
Domain families : Pfam (NCBI)pfam00042   
Conserved Domain (NCBI)CYGB
DMDM Disease mutations114757
Blocks (Seattle)CYGB
PDB (SRS)1UMO    1URV    1URY    1UT0    1UX9    1V5H    2DC3    3AG0    4B3W   
PDB (PDBSum)1UMO    1URV    1URY    1UT0    1UX9    1V5H    2DC3    3AG0    4B3W   
PDB (IMB)1UMO    1URV    1URY    1UT0    1UX9    1V5H    2DC3    3AG0    4B3W   
PDB (RSDB)1UMO    1URV    1URY    1UT0    1UX9    1V5H    2DC3    3AG0    4B3W   
Structural Biology KnowledgeBase1UMO    1URV    1URY    1UT0    1UX9    1V5H    2DC3    3AG0    4B3W   
SCOP (Structural Classification of Proteins)1UMO    1URV    1URY    1UT0    1UX9    1V5H    2DC3    3AG0    4B3W   
CATH (Classification of proteins structures)1UMO    1URV    1URY    1UT0    1UX9    1V5H    2DC3    3AG0    4B3W   
SuperfamilyQ8WWM9
Human Protein AtlasENSG00000161544
Peptide AtlasQ8WWM9
HPRD06479
IPIIPI00103373   
Protein Interaction databases
DIP (DOE-UCLA)Q8WWM9
IntAct (EBI)Q8WWM9
FunCoupENSG00000161544
BioGRIDCYGB
STRING (EMBL)CYGB
ZODIACCYGB
Ontologies - Pathways
QuickGOQ8WWM9
Ontology : AmiGOresponse to hypoxia  catalase activity  peroxidase activity  oxygen transporter activity  iron ion binding  protein binding  cytosol  response to oxidative stress  nitric oxide dioxygenase activity  negative regulation of fibroblast migration  oxygen transport  fatty acid oxidation  oxygen binding  heme binding  negative regulation of collagen biosynthetic process  neuron projection  neuronal cell body  fatty acid peroxidase activity  regulation of nitric-oxide synthase activity  cellular oxidant detoxification  cellular oxidant detoxification  negative regulation of hepatic stellate cell activation  
Ontology : EGO-EBIresponse to hypoxia  catalase activity  peroxidase activity  oxygen transporter activity  iron ion binding  protein binding  cytosol  response to oxidative stress  nitric oxide dioxygenase activity  negative regulation of fibroblast migration  oxygen transport  fatty acid oxidation  oxygen binding  heme binding  negative regulation of collagen biosynthetic process  neuron projection  neuronal cell body  fatty acid peroxidase activity  regulation of nitric-oxide synthase activity  cellular oxidant detoxification  cellular oxidant detoxification  negative regulation of hepatic stellate cell activation  
NDEx NetworkCYGB
Atlas of Cancer Signalling NetworkCYGB
Wikipedia pathwaysCYGB
Orthology - Evolution
OrthoDB114757
GeneTree (enSembl)ENSG00000161544
Phylogenetic Trees/Animal Genes : TreeFamCYGB
HOVERGENQ8WWM9
HOGENOMQ8WWM9
Homologs : HomoloGeneCYGB
Homology/Alignments : Family Browser (UCSC)CYGB
Gene fusions - Rearrangements
Fusion : MitelmanPTPRD/CYGB [9p24.1/17q25.1]  [t(9;17)(p23;q25)]  
Fusion: TCGAPTPRD 9p24.1 CYGB 17q25.1 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYGB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYGB
dbVarCYGB
ClinVarCYGB
1000_GenomesCYGB 
Exome Variant ServerCYGB
ExAC (Exome Aggregation Consortium)CYGB (select the gene name)
Genetic variants : HAPMAP114757
Genomic Variants (DGV)CYGB [DGVbeta]
DECIPHER (Syndromes)17:74523430-74533987  ENSG00000161544
CONAN: Copy Number AnalysisCYGB 
Mutations
ICGC Data PortalCYGB 
TCGA Data PortalCYGB 
Broad Tumor PortalCYGB
OASIS PortalCYGB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYGB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYGB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYGB
DgiDB (Drug Gene Interaction Database)CYGB
DoCM (Curated mutations)CYGB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYGB (select a term)
intoGenCYGB
Cancer3DCYGB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608759   
Orphanet
MedgenCYGB
Genetic Testing Registry CYGB
NextProtQ8WWM9 [Medical]
TSGene114757
GENETestsCYGB
Huge Navigator CYGB [HugePedia]
snp3D : Map Gene to Disease114757
BioCentury BCIQCYGB
ClinGenCYGB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD114757
Chemical/Pharm GKB GenePA27080
Clinical trialCYGB
Miscellaneous
canSAR (ICR)CYGB (select the gene name)
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYGB
EVEXCYGB
GoPubMedCYGB
iHOPCYGB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:02:26 CET 2017

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