Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYP11B1 (cytochrome P450, family 11, subfamily B, polypeptide 1)

Identity

Other namesCPN1
CYP11B
FHI
P450C11
HGNC (Hugo) CYP11B1
LocusID (NCBI) 1584
Location 8q24.3
Location_base_pair Starts at 143953773 and ends at 143961236 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)CYP11B1   2591
Cards
Entrez_Gene (NCBI)CYP11B1  1584  cytochrome P450, family 11, subfamily B, polypeptide 1
GeneCards (Weizmann)CYP11B1
Ensembl (Hinxton)ENSG00000160882 [Gene_View]  chr8:143953773-143961236 [Contig_View]  CYP11B1 [Vega]
ICGC DataPortalENSG00000160882
cBioPortalCYP11B1
AceView (NCBI)CYP11B1
Genatlas (Paris)CYP11B1
WikiGenes1584
SOURCE (Princeton)NM_000497 NM_001026213
Genomic and cartography
GoldenPath (UCSC)CYP11B1  -  8q24.3   chr8:143953773-143961236 -  8q24.3   [Description]    (hg19-Feb_2009)
EnsemblCYP11B1 - 8q24.3 [CytoView]
Mapping of homologs : NCBICYP11B1 [Mapview]
OMIM103900   202010   610613   
Gene and transcription
Genbank (Entrez)AF478474 AK094090 BC096285 BC096286 BC096287
RefSeq transcript (Entrez)NM_000497 NM_001026213
RefSeq genomic (Entrez)AC_000140 NC_000008 NC_018919 NG_007954 NT_008046 NW_001839142 NW_004929340
Consensus coding sequences : CCDS (NCBI)CYP11B1
Cluster EST : UnigeneHs.184927 [ NCBI ]
CGAP (NCI)Hs.184927
Alternative Splicing : Fast-db (Paris)GSHG0029919
Alternative Splicing GalleryENSG00000160882
Gene ExpressionCYP11B1 [ NCBI-GEO ]     CYP11B1 [ SEEK ]   CYP11B1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15538 (Uniprot)
NextProtP15538  [Medical]
With graphics : InterProP15538
Splice isoforms : SwissVarP15538 (Swissvar)
Catalytic activity : Enzyme1.14.15.4 [ Enzyme-Expasy ]   1.14.15.41.14.15.4 [ IntEnz-EBI ]   1.14.15.4 [ BRENDA ]   1.14.15.4 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450 [organisation]   Cyt_P450_CS [organisation]   Cyt_P450_mitochondrial [organisation]  
Related proteins : CluSTrP15538
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
DMDM Disease mutations1584
Blocks (Seattle)P15538
Human Protein AtlasENSG00000160882 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP15538
HPRD01943
IPIIPI00291348   IPI00976758   IPI00167781   IPI00607879   
Protein Interaction databases
DIP (DOE-UCLA)P15538
IntAct (EBI)P15538
FunCoupENSG00000160882
BioGRIDCYP11B1
InParanoidP15538
Interologous Interaction database P15538
IntegromeDBCYP11B1
STRING (EMBL)CYP11B1
Ontologies - Pathways
Ontology : AmiGOsteroid 11-beta-monooxygenase activity  steroid 11-beta-monooxygenase activity  iron ion binding  mitochondrion  mitochondrial inner membrane  mitochondrial inner membrane  C21-steroid hormone biosynthetic process  glucocorticoid biosynthetic process  mineralocorticoid biosynthetic process  xenobiotic metabolic process  immune response  steroid metabolic process  regulation of blood pressure  sterol metabolic process  heme binding  aldosterone biosynthetic process  aldosterone biosynthetic process  cellular response to hormone stimulus  cortisol biosynthetic process  cortisol biosynthetic process  cellular response to potassium ion  glucose homeostasis  small molecule metabolic process  
Ontology : EGO-EBIsteroid 11-beta-monooxygenase activity  steroid 11-beta-monooxygenase activity  iron ion binding  mitochondrion  mitochondrial inner membrane  mitochondrial inner membrane  C21-steroid hormone biosynthetic process  glucocorticoid biosynthetic process  mineralocorticoid biosynthetic process  xenobiotic metabolic process  immune response  steroid metabolic process  regulation of blood pressure  sterol metabolic process  heme binding  aldosterone biosynthetic process  aldosterone biosynthetic process  cellular response to hormone stimulus  cortisol biosynthetic process  cortisol biosynthetic process  cellular response to potassium ion  glucose homeostasis  small molecule metabolic process  
Pathways : KEGGSteroid hormone biosynthesis   
Protein Interaction DatabaseCYP11B1
Wikipedia pathwaysCYP11B1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CYP11B1
snp3D : Map Gene to Disease1584
SNP (GeneSNP Utah)CYP11B1
SNP : HGBaseCYP11B1
Genetic variants : HAPMAPCYP11B1
Exome VariantCYP11B1
1000_GenomesCYP11B1 
ICGC programENSG00000160882 
Somatic Mutations in Cancer : COSMICCYP11B1 
CONAN: Copy Number AnalysisCYP11B1 
Mutations and Diseases : HGMDCYP11B1
Genomic VariantsCYP11B1  CYP11B1 [DGVbeta]
dbVarCYP11B1
ClinVarCYP11B1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM103900    202010    610613   
MedgenCYP11B1
GENETestsCYP11B1
Disease Genetic AssociationCYP11B1
Huge Navigator CYP11B1 [HugePedia]  CYP11B1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCYP11B1
Homology/Alignments : Family Browser (UCSC)CYP11B1
Phylogenetic Trees/Animal Genes : TreeFamCYP11B1
Chemical/Protein Interactions : CTD1584
Chemical/Pharm GKB GenePA133
Clinical trialCYP11B1
Cancer Resource (Charite)ENSG00000160882
Other databases
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
CoreMineCYP11B1
iHOPCYP11B1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 16:52:06 CEST 2014

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