| Nomenclature | | HGNC (Hugo) | CYP19A1 2594 |
| Entrez_Gene (NCBI) | CYP19A1 1588 cytochrome P450, family 19, subfamily A, polypeptide 1 |
| Cards | | GeneCards (Weizmann) | CYP19A1 |
| Ensembl (Hinxton) | ENSG00000137869 [Gene_View] chr15:51500254-51630795 [Contig_View] CYP19A1 [Vega] |
| AceView (NCBI) | CYP19A1 |
| Genatlas (Paris) | CYP19A1 |
| SOURCE (Stanford) | NM_000103 NM_031226 |
| Genomic and cartography | | GoldenPath (UCSC) | CYP19A1 - 15q21.2 chr15:51500254-51630795 - 15q21.2 [Description] (hg19-Feb_2009) |
| Ensembl | CYP19A1 - 15q21.2 [CytoView] |
| Mapping of homologs : NCBI | CYP19A1 [Mapview] |
| OMIM | 107910 139300 613546 |
| Gene and transcription |
| Genbank (Entrez) | AK291778 AM392533 AM393184 BC020767 BC022896 |
| RefSeq transcript (SRS) | NM_000103 NM_031226 |
| RefSeq transcript (Entrez) | NM_000103 NM_031226 |
| RefSeq genomic (SRS) | AC_000147 NC_000015 NC_018926 NG_007982 NT_010194 NW_001838218 NW_004078084 |
| RefSeq genomic (Entrez) | AC_000147 NC_000015 NC_018926 NG_007982 NT_010194 NW_001838218 NW_004078084 |
| Consensus coding sequences : CCDS (NCBI) | CYP19A1 |
| Cluster EST : Unigene | Hs.260074 [ SRS ] Hs.260074 [ NCBI ] |
| CGAP (NCI) | Hs.260074 |
| Alternative Splicing : Fast-db (Paris) | GSHG0010414 |
| Alternative Splicing Gallery | ENSG00000137869 |
| Gene Expression | CYP19A1 [ NCBI-GEO ] CYP19A1 [ EBI - ARRAY_EXPRESS ] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P11511 (SRS) P11511 (Uniprot) |
| NextProt | P11511 |
| With graphics : InterPro | P11511 |
| Splice isoforms : SwissVar | P11511(Swissvar) |
| Domaine pattern : Prosite (SRS) | CYTOCHROME_P450 (PS00086) |
| Domaine pattern : Prosite (Expaxy) | CYTOCHROME_P450 (PS00086) |
| Domains : Interpro (SRS) | Cyt_P450 Cyt_P450_CS Cyt_P450_E_grp-I |
| Domains : Interpro (EBI) | Cyt_P450 Cyt_P450_CS Cyt_P450_E_grp-I |
| Related proteins : CluSTr | P11511 |
| Domain families : Pfam (SRS) | p450 (PF00067) |
| Domain families : Pfam (Sanger) | p450 (PF00067) |
| Domain families : Pfam (NCBI) | pfam00067 |
| DMDM | 1588 |
| Blocks (Seattle) | P11511 |
| PDB (SRS) | 1TQA 3EQM 3S79 3S7S 4GL5 4GL7 |
| PDB (PDBSum) | 1TQA 3EQM 3S79 3S7S 4GL5 4GL7 |
| PDB (IMB) | 1TQA 3EQM 3S79 3S7S 4GL5 4GL7 |
| PDB (RSDB) | 1TQA 3EQM 3S79 3S7S 4GL5 4GL7 |
| Human Protein Atlas | ENSG00000137869 |
| HPRD | 00488 |
| IPI | IPI00465065 IPI00879236 IPI00792386 IPI00878829 IPI00878332 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P11511 |
| IntAct (EBI) | P11511 |
| FunCoup | ENSG00000137869 |
| REACTOME | CYP19A1 |
| Protein Interaction Database | 1588 |
| BioGRID | CYP19A1 |
| InParanoid | P11511 |
| Interologous Interaction database | P11511 |
| IntegromeDB | CYP19A1 |
| Polymorphism : SNP, mutations, diseases | | SNP Single Nucleotide Polymorphism (NCBI) | CYP19A1 |
| SNP (GeneSNP Utah) | CYP19A1 |
| SNP : HGBase | CYP19A1 |
| Genetic variants : HAPMAP | CYP19A1 |
| Somatic Mutations in Cancer : COSMIC | CYP19A1 |
| CONAN: Copy Number Analysis | CYP19A1 |
| Mutations and Diseases : HGMD | CYP19A1 |
| OMIM | 107910 139300 613546 |
| GENETests | 107910 139300 613546 |
| Disease Genetic Association | CYP19A1 |
| Huge Navigator |
CYP19A1 [HugePedia] CYP19A1 [HugeCancerGEM] |
| Genomic Variants | CYP19A1 CYP19A1 [DGVbeta] |
| snp3D : Map Gene to Disease | 1588 |
| General knowledge |
|---|
| Homologs : HomoloGene | CYP19A1 |
| Homology/Alignments : Family Browser (UCSC) | CYP19A1 |
| Phylogenetic Trees/Animal Genes : TreeFam | CYP19A1 |
| Catalytic activity : Enzyme | 1.14.14.1 [ Enzyme-Expasy ] 1.14.14.1 [ Enzyme-SRS ] 1.14.14.1 [ IntEnz-EBI ] 1.14.14.1 [ BRENDA ] 1.14.14.1 [ KEGG ] |
| Chemical/Protein Interactions : CTD | 1588 |
| Chemical/Pharm GKB Gene | PA27091 |
| Clinical trial | CYP19A1 |
| Cancer Resource (Charite) | ENSG00000137869 |
| Ontology : AmiGO | iron ion binding endoplasmic reticulum endoplasmic reticulum membrane cytosol steroid biosynthetic process estrogen biosynthetic process xenobiotic metabolic process synaptic vesicle steroid metabolic process bile acid metabolic process androgen metabolic process male gonad development electron carrier activity response to herbicide response to cesium ion response to ionizing radiation membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen biphenyl metabolic process dibenzo-p-dioxin metabolic process phthalate metabolic process oxygen binding heme binding hippocampus development hypothalamus development melatonin metabolic process adrenal gland development granulocyte differentiation response to estradiol stimulus response to testosterone stimulus progesterone metabolic process response to drug neuronal cell body terminal button dendritic spine response to morphine small molecule metabolic process cellular response to fibroblast growth factor stimulus regulation of synapse structure and activity bone development prostate gland growth aromatase activity cellular response to glucose stimulus cellular response to follicle-stimulating hormone stimulus cellular response to hydrostatic pressure |
| Ontology : EGO-EBI | iron ion binding endoplasmic reticulum endoplasmic reticulum membrane cytosol steroid biosynthetic process estrogen biosynthetic process xenobiotic metabolic process synaptic vesicle steroid metabolic process bile acid metabolic process androgen metabolic process male gonad development electron carrier activity response to herbicide response to cesium ion response to ionizing radiation membrane oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen biphenyl metabolic process dibenzo-p-dioxin metabolic process phthalate metabolic process oxygen binding heme binding hippocampus development hypothalamus development melatonin metabolic process adrenal gland development granulocyte differentiation response to estradiol stimulus response to testosterone stimulus progesterone metabolic process response to drug neuronal cell body terminal button dendritic spine response to morphine small molecule metabolic process cellular response to fibroblast growth factor stimulus regulation of synapse structure and activity bone development prostate gland growth aromatase activity cellular response to glucose stimulus cellular response to follicle-stimulating hormone stimulus cellular response to hydrostatic pressure |
| Other databases |
| Probes |
|---|
| Litterature | | PubMed | 499 Pubmed reference(s) in Entrez |
| PubGene | CYP19A1 |
| iHOP | CYP19A1 |
