Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CYP24A1 (cytochrome P450, family 24, subfamily A, polypeptide 1)

Identity

Other namesCP24
CYP24
HCAI
P450-CC24
HGNC (Hugo) CYP24A1
LocusID (NCBI) 1591
Location 20q13.2
Location_base_pair Starts at 52769988 and ends at 52790516 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CYP24A1   2602
Entrez_Gene (NCBI)CYP24A1  1591  cytochrome P450, family 24, subfamily A, polypeptide 1
Cards
GeneCards (Weizmann)CYP24A1
Ensembl (Hinxton)ENSG00000019186 [Gene_View]  chr20:52769988-52790516 [Contig_View]  CYP24A1 [Vega]
AceView (NCBI)CYP24A1
Genatlas (Paris)CYP24A1
SOURCE (Stanford)NM_000782 NM_001128915
Genomic and cartography
GoldenPath (UCSC)CYP24A1  -  20q13.2   chr20:52769988-52790516 -  20q13.2   [Description]    (hg19-Feb_2009)
EnsemblCYP24A1 - 20q13.2 [CytoView]
Mapping of homologs : NCBICYP24A1 [Mapview]
OMIM126065   143880   
Gene and transcription
Genbank (Entrez)AI400154 AW022349 AY858838 BC109083 BC109084
RefSeq transcript (SRS)NM_000782 NM_001128915
RefSeq transcript (Entrez)NM_000782 NM_001128915
RefSeq genomic (SRS)AC_000152 NC_000020 NC_018931 NG_008334 NT_011362 NW_001838666 NW_004078102
RefSeq genomic (Entrez)AC_000152 NC_000020 NC_018931 NG_008334 NT_011362 NW_001838666 NW_004078102
Consensus coding sequences : CCDS (NCBI)CYP24A1
Cluster EST : UnigeneHs.89663 [ SRS ] Hs.89663 [ NCBI ]
CGAP (NCI)Hs.89663
Alternative Splicing : Fast-db (Paris)GSHG0019273
Alternative Splicing GalleryENSG00000019186
Gene ExpressionCYP24A1 [ NCBI-GEO ]   CYP24A1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ07973 (SRS) Q07973 (Uniprot)
NextProtQ07973
With graphics : InterProQ07973
Splice isoforms : SwissVarQ07973(Swissvar)
Domaine pattern : Prosite (SRS)CYTOCHROME_P450 (PS00086)   
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (SRS)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I   
Related proteins : CluSTrQ07973
Domain families : Pfam (SRS)p450 (PF00067)   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
DMDM1591
Blocks (Seattle)Q07973
Human Protein AtlasENSG00000019186
HPRD00522
IPIIPI00020586   IPI00656023   IPI00796070   
Protein Interaction databases
DIP (DOE-UCLA)Q07973
IntAct (EBI)Q07973
FunCoupENSG00000019186
REACTOMECYP24A1
Protein Interaction Database1591
BioGRIDCYP24A1
InParanoidQ07973
Interologous Interaction database Q07973
IntegromeDBCYP24A1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CYP24A1
SNP (GeneSNP Utah)CYP24A1
SNP : HGBaseCYP24A1
Genetic variants : HAPMAPCYP24A1
Somatic Mutations in Cancer : COSMICCYP24A1 
CONAN: Copy Number AnalysisCYP24A1 
Mutations and Diseases : HGMDCYP24A1
OMIM126065    143880   
GENETests126065    143880   
Disease Genetic AssociationCYP24A1
Huge Navigator CYP24A1 [HugePedia]  CYP24A1 [HugeCancerGEM]
Genomic VariantsCYP24A1  CYP24A1 [DGVbeta]
snp3D : Map Gene to Disease1591
General knowledge
Homologs : HomoloGeneCYP24A1
Homology/Alignments : Family Browser (UCSC)CYP24A1
Phylogenetic Trees/Animal Genes : TreeFamCYP24A1
Catalytic activity : Enzyme1.14.13.126 [ Enzyme-Expasy ]   1.14.13.126 [ Enzyme-SRS ]   1.14.13.126 [ IntEnz-EBI ]   1.14.13.126 [ BRENDA ]   1.14.13.126 [ KEGG ]   
Chemical/Protein Interactions : CTD1591
Chemical/Pharm GKB GenePA27097
Clinical trialCYP24A1
Cancer Resource (Charite)ENSG00000019186
Ontology : AmiGOosteoblast differentiation  iron ion binding  mitochondrial inner membrane  vitamin metabolic process  xenobiotic metabolic process  steroid metabolic process  25-hydroxycholecalciferol-24-hydroxylase activity  electron carrier activity  oxidoreductase activity  heme binding  1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity  response to vitamin D  vitamin D metabolic process  vitamin D catabolic process  small molecule metabolic process  oxidation-reduction process  vitamin D receptor signaling pathway  vitamin D receptor signaling pathway  
Ontology : EGO-EBIosteoblast differentiation  iron ion binding  mitochondrial inner membrane  vitamin metabolic process  xenobiotic metabolic process  steroid metabolic process  25-hydroxycholecalciferol-24-hydroxylase activity  electron carrier activity  oxidoreductase activity  heme binding  1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity  response to vitamin D  vitamin D metabolic process  vitamin D catabolic process  small molecule metabolic process  oxidation-reduction process  vitamin D receptor signaling pathway  vitamin D receptor signaling pathway  
Pathways : BIOCARTANuclear Receptors in Lipid Metabolism and Toxicity [Genes]   
Other databases
Probes
Litterature
PubMed103 Pubmed reference(s) in Entrez
PubGeneCYP24A1
iHOPCYP24A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:22:16 CEST 2013
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