Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYP24A1 (cytochrome P450, family 24, subfamily A, polypeptide 1)

Identity

Other namesCP24
CYP24
HCAI
P450-CC24
HGNC (Hugo) CYP24A1
LocusID (NCBI) 1591
Location 20q13.2
Location_base_pair Starts at 52769988 and ends at 52790516 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CYP24A1   2602
Cards
Entrez_Gene (NCBI)CYP24A1  1591  cytochrome P450, family 24, subfamily A, polypeptide 1
GeneCards (Weizmann)CYP24A1
Ensembl (Hinxton)ENSG00000019186 [Gene_View]  chr20:52769988-52790516 [Contig_View]  CYP24A1 [Vega]
ICGC DataPortalENSG00000019186
cBioPortalCYP24A1
AceView (NCBI)CYP24A1
Genatlas (Paris)CYP24A1
WikiGenes1591
SOURCE (Princeton)NM_000782 NM_001128915
Genomic and cartography
GoldenPath (UCSC)CYP24A1  -  20q13.2   chr20:52769988-52790516 -  20q13.2   [Description]    (hg19-Feb_2009)
EnsemblCYP24A1 - 20q13.2 [CytoView]
Mapping of homologs : NCBICYP24A1 [Mapview]
OMIM126065   143880   
Gene and transcription
Genbank (Entrez)AI400154 AW022349 AY858838 BC109083 BC109084
RefSeq transcript (Entrez)NM_000782 NM_001128915
RefSeq genomic (Entrez)AC_000152 NC_000020 NC_018931 NG_008334 NT_011362 NW_001838666 NW_004929418
Consensus coding sequences : CCDS (NCBI)CYP24A1
Cluster EST : UnigeneHs.89663 [ NCBI ]
CGAP (NCI)Hs.89663
Alternative Splicing : Fast-db (Paris)GSHG0019273
Alternative Splicing GalleryENSG00000019186
Gene ExpressionCYP24A1 [ NCBI-GEO ]     CYP24A1 [ SEEK ]   CYP24A1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ07973 (Uniprot)
NextProtQ07973  [Medical]
With graphics : InterProQ07973
Splice isoforms : SwissVarQ07973 (Swissvar)
Catalytic activity : Enzyme1.14.13.126 [ Enzyme-Expasy ]   1.14.13.1261.14.13.126 [ IntEnz-EBI ]   1.14.13.126 [ BRENDA ]   1.14.13.126 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450 [organisation]   Cyt_P450_CS [organisation]   Cyt_P450_E_grp-I [organisation]  
Related proteins : CluSTrQ07973
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
DMDM Disease mutations1591
Blocks (Seattle)Q07973
Human Protein AtlasENSG00000019186 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ07973
HPRD00522
IPIIPI00020586   IPI00656023   IPI00796070   
Protein Interaction databases
DIP (DOE-UCLA)Q07973
IntAct (EBI)Q07973
FunCoupENSG00000019186
BioGRIDCYP24A1
InParanoidQ07973
Interologous Interaction database Q07973
IntegromeDBCYP24A1
STRING (EMBL)CYP24A1
Ontologies - Pathways
Ontology : AmiGOosteoblast differentiation  iron ion binding  mitochondrial inner membrane  vitamin metabolic process  xenobiotic metabolic process  steroid metabolic process  25-hydroxycholecalciferol-24-hydroxylase activity  oxidoreductase activity  heme binding  1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity  response to vitamin D  vitamin D metabolic process  vitamin D catabolic process  small molecule metabolic process  oxidation-reduction process  vitamin D receptor signaling pathway  
Ontology : EGO-EBIosteoblast differentiation  iron ion binding  mitochondrial inner membrane  vitamin metabolic process  xenobiotic metabolic process  steroid metabolic process  25-hydroxycholecalciferol-24-hydroxylase activity  oxidoreductase activity  heme binding  1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity  response to vitamin D  vitamin D metabolic process  vitamin D catabolic process  small molecule metabolic process  oxidation-reduction process  vitamin D receptor signaling pathway  
Pathways : BIOCARTANuclear Receptors in Lipid Metabolism and Toxicity [Genes]   
Pathways : KEGGSteroid biosynthesis    MicroRNAs in cancer   
Protein Interaction DatabaseCYP24A1
Wikipedia pathwaysCYP24A1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CYP24A1
snp3D : Map Gene to Disease1591
SNP (GeneSNP Utah)CYP24A1
SNP : HGBaseCYP24A1
Genetic variants : HAPMAPCYP24A1
Exome VariantCYP24A1
1000_GenomesCYP24A1 
ICGC programENSG00000019186 
Somatic Mutations in Cancer : COSMICCYP24A1 
CONAN: Copy Number AnalysisCYP24A1 
Mutations and Diseases : HGMDCYP24A1
Mutations and Diseases : intOGenCYP24A1
Genomic VariantsCYP24A1  CYP24A1 [DGVbeta]
dbVarCYP24A1
ClinVarCYP24A1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM126065    143880   
MedgenCYP24A1
GENETestsCYP24A1
Disease Genetic AssociationCYP24A1
Huge Navigator CYP24A1 [HugePedia]  CYP24A1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCYP24A1
Homology/Alignments : Family Browser (UCSC)CYP24A1
Phylogenetic Trees/Animal Genes : TreeFamCYP24A1
Chemical/Protein Interactions : CTD1591
Chemical/Pharm GKB GenePA27097
Clinical trialCYP24A1
Cancer Resource (Charite)ENSG00000019186
Other databases
Probes
Litterature
PubMed125 Pubmed reference(s) in Entrez
CoreMineCYP24A1
iHOPCYP24A1
OncoSearchCYP24A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 18:46:59 CEST 2014

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