Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CYP26B1 (cytochrome P450 family 26 subfamily B member 1)

Identity

Alias_namescytochrome P450, family 26, subfamily B, polypeptide 1
cytochrome P450 family 26 subfamily A member 1
Alias_symbol (synonym)P450RAI-2
HGNC (Hugo) CYP26B1
LocusID (NCBI) 56603
Atlas_Id 52458
Location 2p13.2  [Link to chromosome band 2p13]
Location_base_pair Starts at 72356367 and ends at 72374991 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP26B1   20581
Cards
Entrez_Gene (NCBI)CYP26B1  56603  cytochrome P450 family 26 subfamily B member 1
AliasesCYP26A2; P450RAI-2; P450RAI2; RHFCA
GeneCards (Weizmann)CYP26B1
Ensembl hg19 (Hinxton)ENSG00000003137 [Gene_View]  chr2:72356367-72374991 [Contig_View]  CYP26B1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000003137 [Gene_View]  chr2:72356367-72374991 [Contig_View]  CYP26B1 [Vega]
ICGC DataPortalENSG00000003137
TCGA cBioPortalCYP26B1
AceView (NCBI)CYP26B1
Genatlas (Paris)CYP26B1
WikiGenes56603
SOURCE (Princeton)CYP26B1
Genetics Home Reference (NIH)CYP26B1
Genomic and cartography
GoldenPath hg19 (UCSC)CYP26B1  -     chr2:72356367-72374991 -  2p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CYP26B1  -     2p13.2   [Description]    (hg38-Dec_2013)
EnsemblCYP26B1 - 2p13.2 [CytoView hg19]  CYP26B1 - 2p13.2 [CytoView hg38]
Mapping of homologs : NCBICYP26B1 [Mapview hg19]  CYP26B1 [Mapview hg38]
OMIM605207   614416   
Gene and transcription
Genbank (Entrez)AA484668 AF252297 AK294814 AK294933 AK295683
RefSeq transcript (Entrez)NM_001277742 NM_019885
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_007957 NT_022184 NW_004929300
Consensus coding sequences : CCDS (NCBI)CYP26B1
Cluster EST : UnigeneHs.91546 [ NCBI ]
CGAP (NCI)Hs.91546
Alternative Splicing GalleryENSG00000003137
Gene ExpressionCYP26B1 [ NCBI-GEO ]   CYP26B1 [ EBI - ARRAY_EXPRESS ]   CYP26B1 [ SEEK ]   CYP26B1 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP26B1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56603
GTEX Portal (Tissue expression)CYP26B1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NR63   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NR63  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NR63
Splice isoforms : SwissVarQ9NR63
Catalytic activity : Enzyme1.14.-.- [ Enzyme-Expasy ]   1.14.-.-1.14.-.- [ IntEnz-EBI ]   1.14.-.- [ BRENDA ]   1.14.-.- [ KEGG ]   
PhosPhoSitePlusQ9NR63
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-IV   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP26B1
DMDM Disease mutations56603
Blocks (Seattle)CYP26B1
SuperfamilyQ9NR63
Human Protein AtlasENSG00000003137
Peptide AtlasQ9NR63
HPRD05550
IPIIPI00008398   IPI00952755   IPI00917715   IPI00983422   
Protein Interaction databases
DIP (DOE-UCLA)Q9NR63
IntAct (EBI)Q9NR63
FunCoupENSG00000003137
BioGRIDCYP26B1
STRING (EMBL)CYP26B1
ZODIACCYP26B1
Ontologies - Pathways
QuickGOQ9NR63
Ontology : AmiGOcell fate determination  establishment of T cell polarity  retinoic acid binding  iron ion binding  cytoplasm  endoplasmic reticulum membrane  vitamin metabolic process  inflammatory response  male meiosis  spermatogenesis  retinoic acid 4-hydroxylase activity  retinoic acid 4-hydroxylase activity  proximal/distal pattern formation  positive regulation of gene expression  heme binding  embryonic limb morphogenesis  retinoic acid catabolic process  tongue morphogenesis  regulation of T cell differentiation  retinoic acid receptor signaling pathway  negative regulation of retinoic acid receptor signaling pathway  oxidation-reduction process  bone morphogenesis  establishment of skin barrier  cornification  cellular response to retinoic acid  positive regulation of tongue muscle cell differentiation  
Ontology : EGO-EBIcell fate determination  establishment of T cell polarity  retinoic acid binding  iron ion binding  cytoplasm  endoplasmic reticulum membrane  vitamin metabolic process  inflammatory response  male meiosis  spermatogenesis  retinoic acid 4-hydroxylase activity  retinoic acid 4-hydroxylase activity  proximal/distal pattern formation  positive regulation of gene expression  heme binding  embryonic limb morphogenesis  retinoic acid catabolic process  tongue morphogenesis  regulation of T cell differentiation  retinoic acid receptor signaling pathway  negative regulation of retinoic acid receptor signaling pathway  oxidation-reduction process  bone morphogenesis  establishment of skin barrier  cornification  cellular response to retinoic acid  positive regulation of tongue muscle cell differentiation  
Pathways : KEGGRetinol metabolism   
NDEx NetworkCYP26B1
Atlas of Cancer Signalling NetworkCYP26B1
Wikipedia pathwaysCYP26B1
Orthology - Evolution
OrthoDB56603
GeneTree (enSembl)ENSG00000003137
Phylogenetic Trees/Animal Genes : TreeFamCYP26B1
HOVERGENQ9NR63
HOGENOMQ9NR63
Homologs : HomoloGeneCYP26B1
Homology/Alignments : Family Browser (UCSC)CYP26B1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP26B1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP26B1
dbVarCYP26B1
ClinVarCYP26B1
1000_GenomesCYP26B1 
Exome Variant ServerCYP26B1
ExAC (Exome Aggregation Consortium)CYP26B1 (select the gene name)
Genetic variants : HAPMAP56603
Genomic Variants (DGV)CYP26B1 [DGVbeta]
DECIPHER (Syndromes)2:72356367-72374991  ENSG00000003137
CONAN: Copy Number AnalysisCYP26B1 
Mutations
ICGC Data PortalCYP26B1 
TCGA Data PortalCYP26B1 
Broad Tumor PortalCYP26B1
OASIS PortalCYP26B1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP26B1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYP26B1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYP26B1
DgiDB (Drug Gene Interaction Database)CYP26B1
DoCM (Curated mutations)CYP26B1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP26B1 (select a term)
intoGenCYP26B1
Cancer3DCYP26B1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605207    614416   
Orphanet20889   
MedgenCYP26B1
Genetic Testing Registry CYP26B1
NextProtQ9NR63 [Medical]
TSGene56603
GENETestsCYP26B1
Huge Navigator CYP26B1 [HugePedia]
snp3D : Map Gene to Disease56603
BioCentury BCIQCYP26B1
ClinGenCYP26B1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56603
Chemical/Pharm GKB GenePA134879191
Clinical trialCYP26B1
Miscellaneous
canSAR (ICR)CYP26B1 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP26B1
EVEXCYP26B1
GoPubMedCYP26B1
iHOPCYP26B1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Nov 18 19:35:13 CET 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.