Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYP2A7 (cytochrome P450 family 2 subfamily A member 7)

Identity

Other aliasCPA7
CPAD
CYP2A
CYPIIA7
P450-IIA4
HGNC (Hugo) CYP2A7
LocusID (NCBI) 1549
Atlas_Id 57197
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 40875613 and ends at 40882255 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLPTM1 (19q13.32) / CYP2A7 (19q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP2A7   2611
Cards
Entrez_Gene (NCBI)CYP2A7  1549  cytochrome P450 family 2 subfamily A member 7
AliasesCPA7; CPAD; CYP2A; CYPIIA7; 
P450-IIA4
GeneCards (Weizmann)CYP2A7
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr19:40875613-40882255 [Contig_View]  CYP2A7 [Vega]
TCGA cBioPortalCYP2A7
AceView (NCBI)CYP2A7
Genatlas (Paris)CYP2A7
WikiGenes1549
SOURCE (Princeton)CYP2A7
Genetics Home Reference (NIH)CYP2A7
Genomic and cartography
GoldenPath hg38 (UCSC)CYP2A7  -     chr19:40875613-40882255 -  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYP2A7  -     19q13.2   [Description]    (hg19-Feb_2009)
EnsemblCYP2A7 - 19q13.2 [CytoView hg19]  CYP2A7 - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBICYP2A7 [Mapview hg19]  CYP2A7 [Mapview hg38]
OMIM608054   
Gene and transcription
Genbank (Entrez)BC117165 BC143325 M33317 U22029
RefSeq transcript (Entrez)NM_000764 NM_030589
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYP2A7
Cluster EST : UnigeneHs.719890 [ NCBI ]
CGAP (NCI)Hs.719890
Gene ExpressionCYP2A7 [ NCBI-GEO ]   CYP2A7 [ EBI - ARRAY_EXPRESS ]   CYP2A7 [ SEEK ]   CYP2A7 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP2A7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1549
GTEX Portal (Tissue expression)CYP2A7
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20853   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20853  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20853
Splice isoforms : SwissVarP20853
Catalytic activity : Enzyme1.14.14.1 [ Enzyme-Expasy ]   1.14.14.11.14.14.1 [ IntEnz-EBI ]   1.14.14.1 [ BRENDA ]   1.14.14.1 [ KEGG ]   
PhosPhoSitePlusP20853
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I    Cyt_P450_E_grp-I_CYP2A-like   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP2A7
DMDM Disease mutations1549
Blocks (Seattle)CYP2A7
SuperfamilyP20853
Peptide AtlasP20853
IPIIPI00302839   IPI00940937   IPI00873572   
Protein Interaction databases
DIP (DOE-UCLA)P20853
IntAct (EBI)P20853
BioGRIDCYP2A7
STRING (EMBL)CYP2A7
ZODIACCYP2A7
Ontologies - Pathways
QuickGOP20853
Ontology : AmiGOiron ion binding  endoplasmic reticulum membrane  arachidonic acid epoxygenase activity  steroid hydroxylase activity  epoxygenase P450 pathway  oxygen binding  heme binding  organelle membrane  oxidation-reduction process  aromatase activity  
Ontology : EGO-EBIiron ion binding  endoplasmic reticulum membrane  arachidonic acid epoxygenase activity  steroid hydroxylase activity  epoxygenase P450 pathway  oxygen binding  heme binding  organelle membrane  oxidation-reduction process  aromatase activity  
NDEx NetworkCYP2A7
Atlas of Cancer Signalling NetworkCYP2A7
Wikipedia pathwaysCYP2A7
Orthology - Evolution
OrthoDB1549
Phylogenetic Trees/Animal Genes : TreeFamCYP2A7
HOVERGENP20853
HOGENOMP20853
Homologs : HomoloGeneCYP2A7
Homology/Alignments : Family Browser (UCSC)CYP2A7
Gene fusions - Rearrangements
Fusion: Tumor Portal CYP2A7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP2A7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP2A7
dbVarCYP2A7
ClinVarCYP2A7
1000_GenomesCYP2A7 
Exome Variant ServerCYP2A7
ExAC (Exome Aggregation Consortium)
Genetic variants : HAPMAP1549
Genomic Variants (DGV)CYP2A7 [DGVbeta]
DECIPHERCYP2A7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYP2A7 
Mutations
ICGC Data PortalCYP2A7 
TCGA Data PortalCYP2A7 
Broad Tumor PortalCYP2A7
OASIS PortalCYP2A7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP2A7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYP2A7
BioMutasearch CYP2A7
DgiDB (Drug Gene Interaction Database)CYP2A7
DoCM (Curated mutations)CYP2A7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP2A7 (select a term)
intoGenCYP2A7
Cancer3DCYP2A7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608054   
Orphanet
MedgenCYP2A7
Genetic Testing Registry CYP2A7
NextProtP20853 [Medical]
TSGene1549
GENETestsCYP2A7
Target ValidationCYP2A7
Huge Navigator CYP2A7 [HugePedia]
snp3D : Map Gene to Disease1549
BioCentury BCIQCYP2A7
ClinGenCYP2A7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1549
Chemical/Pharm GKB GenePA27102
Clinical trialCYP2A7
Miscellaneous
canSAR (ICR)CYP2A7 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP2A7
EVEXCYP2A7
GoPubMedCYP2A7
iHOPCYP2A7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:46:38 CET 2017

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