Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene))

Identity

Alias_namesCYP2D
CYP2D@
CYP2D7P1
CYP2D7P
cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing) cluster
cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 1
cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene)
Other aliasCYP2D7AP
P450C2D
P450DB1
RNA40057
HGNC (Hugo) CYP2D7
LocusID (NCBI) 1564
Atlas_Id 62253
Location 22q13.2  [Link to chromosome band 22q13]
Location_base_pair Starts at 42139591 and ends at 42144575 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP2D7   2624
Cards
Entrez_Gene (NCBI)CYP2D7  1564  cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)
AliasesCYP2D; CYP2D7AP; CYP2D7P; CYP2D7P1; 
CYP2D@; P450C2D; P450DB1; RNA40057
GeneCards (Weizmann)CYP2D7
Ensembl hg19 (Hinxton)ENSG00000205702 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205702 [Gene_View]  chr22:42139591-42144575 [Contig_View]  CYP2D7 [Vega]
ICGC DataPortalENSG00000205702
TCGA cBioPortalCYP2D7
AceView (NCBI)CYP2D7
Genatlas (Paris)CYP2D7
WikiGenes1564
SOURCE (Princeton)CYP2D7
Genetics Home Reference (NIH)CYP2D7
Genomic and cartography
GoldenPath hg38 (UCSC)CYP2D7  -     chr22:42139591-42144575 -  22q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYP2D7  -     22q13.2   [Description]    (hg19-Feb_2009)
EnsemblCYP2D7 - 22q13.2 [CytoView hg19]  CYP2D7 - 22q13.2 [CytoView hg38]
Mapping of homologs : NCBICYP2D7 [Mapview hg19]  CYP2D7 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK308043 AY220845 BC108679 X07619 X07620
RefSeq transcript (Entrez)NM_001348386
RefSeq genomic (Entrez)NC_000022 NC_018933 NG_002362 NT_187682 NW_003315971 NW_009646207 NW_009646208 NW_014040930 NW_014040931 NW_015148968
Consensus coding sequences : CCDS (NCBI)CYP2D7
Cluster EST : UnigeneHs.333497 [ NCBI ]
CGAP (NCI)Hs.333497
Alternative Splicing GalleryENSG00000205702
Gene ExpressionCYP2D7 [ NCBI-GEO ]   CYP2D7 [ EBI - ARRAY_EXPRESS ]   CYP2D7 [ SEEK ]   CYP2D7 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP2D7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1564
GTEX Portal (Tissue expression)CYP2D7
Protein : pattern, domain, 3D structure
UniProt/SwissProtA0A087X1C5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA0A087X1C5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA0A087X1C5
Splice isoforms : SwissVarA0A087X1C5
PhosPhoSitePlusA0A087X1C5
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I    Cyt_P450_E_grp-I_CYP2D-like   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP2D7
DMDM Disease mutations1564
Blocks (Seattle)CYP2D7
SuperfamilyA0A087X1C5
Human Protein AtlasENSG00000205702
Peptide AtlasA0A087X1C5
HPRD13108
IPIIPI00970861   IPI01012300   IPI00969560   IPI01009344   IPI01010620   
Protein Interaction databases
DIP (DOE-UCLA)A0A087X1C5
IntAct (EBI)A0A087X1C5
FunCoupENSG00000205702
BioGRIDCYP2D7
STRING (EMBL)CYP2D7
ZODIACCYP2D7
Ontologies - Pathways
QuickGOA0A087X1C5
Ontology : AmiGOiron ion binding  cytoplasm  mitochondrion  xenobiotic metabolic process  xenobiotic metabolic process  integral component of membrane  arachidonic acid metabolic process  heme binding  exogenous drug catabolic process  exogenous drug catabolic process  oxidation-reduction process  aromatase activity  aromatase activity  
Ontology : EGO-EBIiron ion binding  cytoplasm  mitochondrion  xenobiotic metabolic process  xenobiotic metabolic process  integral component of membrane  arachidonic acid metabolic process  heme binding  exogenous drug catabolic process  exogenous drug catabolic process  oxidation-reduction process  aromatase activity  aromatase activity  
NDEx NetworkCYP2D7
Atlas of Cancer Signalling NetworkCYP2D7
Wikipedia pathwaysCYP2D7
Orthology - Evolution
OrthoDB1564
GeneTree (enSembl)ENSG00000205702
Phylogenetic Trees/Animal Genes : TreeFamCYP2D7
HOVERGENA0A087X1C5
HOGENOMA0A087X1C5
Homologs : HomoloGeneCYP2D7
Homology/Alignments : Family Browser (UCSC)CYP2D7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP2D7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP2D7
dbVarCYP2D7
ClinVarCYP2D7
1000_GenomesCYP2D7 
Exome Variant ServerCYP2D7
ExAC (Exome Aggregation Consortium)CYP2D7 (select the gene name)
Genetic variants : HAPMAP1564
Genomic Variants (DGV)CYP2D7 [DGVbeta]
DECIPHERCYP2D7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYP2D7 
Mutations
ICGC Data PortalCYP2D7 
TCGA Data PortalCYP2D7 
Broad Tumor PortalCYP2D7
OASIS PortalCYP2D7 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCYP2D7
BioMutasearch CYP2D7
DgiDB (Drug Gene Interaction Database)CYP2D7
DoCM (Curated mutations)CYP2D7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP2D7 (select a term)
intoGenCYP2D7
Cancer3DCYP2D7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenCYP2D7
Genetic Testing Registry CYP2D7
NextProtA0A087X1C5 [Medical]
TSGene1564
GENETestsCYP2D7
Target ValidationCYP2D7
Huge Navigator CYP2D7 [HugePedia]
snp3D : Map Gene to Disease1564
BioCentury BCIQCYP2D7
ClinGenCYP2D7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1564
Chemical/Pharm GKB GenePA134926902
Clinical trialCYP2D7
Miscellaneous
canSAR (ICR)CYP2D7 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP2D7
EVEXCYP2D7
GoPubMedCYP2D7
iHOPCYP2D7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:45:06 CEST 2017

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