Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYP2J2 (cytochrome P450 family 2 subfamily J member 2)

Identity

Alias_namescytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2
cytochrome P450, family 2, subfamily J, polypeptide 2
Other aliasCPJ2
CYPIIJ2
HGNC (Hugo) CYP2J2
LocusID (NCBI) 1573
Atlas_Id 49722
Location 1p32.1  [Link to chromosome band 1p32]
Location_base_pair Starts at 60358980 and ends at 60392470 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NFIA (1p31.3) / CYP2J2 (1p32.1)NFIA 1p31.3 / CYP2J2 1p32.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP2J2   2634
Cards
Entrez_Gene (NCBI)CYP2J2  1573  cytochrome P450 family 2 subfamily J member 2
AliasesCPJ2; CYPIIJ2
GeneCards (Weizmann)CYP2J2
Ensembl hg19 (Hinxton)ENSG00000134716 [Gene_View]  chr1:60358980-60392470 [Contig_View]  CYP2J2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000134716 [Gene_View]  chr1:60358980-60392470 [Contig_View]  CYP2J2 [Vega]
ICGC DataPortalENSG00000134716
TCGA cBioPortalCYP2J2
AceView (NCBI)CYP2J2
Genatlas (Paris)CYP2J2
WikiGenes1573
SOURCE (Princeton)CYP2J2
Genetics Home Reference (NIH)CYP2J2
Genomic and cartography
GoldenPath hg19 (UCSC)CYP2J2  -     chr1:60358980-60392470 -  1p32.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CYP2J2  -     1p32.1   [Description]    (hg38-Dec_2013)
EnsemblCYP2J2 - 1p32.1 [CytoView hg19]  CYP2J2 - 1p32.1 [CytoView hg38]
Mapping of homologs : NCBICYP2J2 [Mapview hg19]  CYP2J2 [Mapview hg38]
OMIM601258   
Gene and transcription
Genbank (Entrez)AB080265 AF144566 AK055088 AK315387 BC032594
RefSeq transcript (Entrez)NM_000775
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_007931 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)CYP2J2
Cluster EST : UnigeneHs.152096 [ NCBI ]
CGAP (NCI)Hs.152096
Alternative Splicing GalleryENSG00000134716
Gene ExpressionCYP2J2 [ NCBI-GEO ]   CYP2J2 [ EBI - ARRAY_EXPRESS ]   CYP2J2 [ SEEK ]   CYP2J2 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP2J2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1573
GTEX Portal (Tissue expression)CYP2J2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51589   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51589  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51589
Splice isoforms : SwissVarP51589
Catalytic activity : Enzyme1.14.14.1 [ Enzyme-Expasy ]   1.14.14.11.14.14.1 [ IntEnz-EBI ]   1.14.14.1 [ BRENDA ]   1.14.14.1 [ KEGG ]   
PhosPhoSitePlusP51589
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I    Cyt_P450_E_grp-I_CYP2J-like   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP2J2
DMDM Disease mutations1573
Blocks (Seattle)CYP2J2
SuperfamilyP51589
Human Protein AtlasENSG00000134716
Peptide AtlasP51589
HPRD03159
IPIIPI00019411   
Protein Interaction databases
DIP (DOE-UCLA)P51589
IntAct (EBI)P51589
FunCoupENSG00000134716
BioGRIDCYP2J2
STRING (EMBL)CYP2J2
ZODIACCYP2J2
Ontologies - Pathways
QuickGOP51589
Ontology : AmiGOmonooxygenase activity  iron ion binding  endoplasmic reticulum membrane  icosanoid metabolic process  xenobiotic metabolic process  regulation of heart contraction  arachidonic acid epoxygenase activity  arachidonic acid epoxygenase activity  steroid hydroxylase activity  arachidonic acid 14,15-epoxygenase activity  arachidonic acid 11,12-epoxygenase activity  epoxygenase P450 pathway  epoxygenase P450 pathway  heme binding  linoleic acid metabolic process  oxidation-reduction process  extracellular exosome  aromatase activity  linoleic acid epoxygenase activity  
Ontology : EGO-EBImonooxygenase activity  iron ion binding  endoplasmic reticulum membrane  icosanoid metabolic process  xenobiotic metabolic process  regulation of heart contraction  arachidonic acid epoxygenase activity  arachidonic acid epoxygenase activity  steroid hydroxylase activity  arachidonic acid 14,15-epoxygenase activity  arachidonic acid 11,12-epoxygenase activity  epoxygenase P450 pathway  epoxygenase P450 pathway  heme binding  linoleic acid metabolic process  oxidation-reduction process  extracellular exosome  aromatase activity  linoleic acid epoxygenase activity  
Pathways : BIOCARTAEicosanoid Metabolism [Genes]   
Pathways : KEGGArachidonic acid metabolism    Linoleic acid metabolism    Serotonergic synapse    Ovarian steroidogenesis   
NDEx NetworkCYP2J2
Atlas of Cancer Signalling NetworkCYP2J2
Wikipedia pathwaysCYP2J2
Orthology - Evolution
OrthoDB1573
GeneTree (enSembl)ENSG00000134716
Phylogenetic Trees/Animal Genes : TreeFamCYP2J2
HOVERGENP51589
HOGENOMP51589
Homologs : HomoloGeneCYP2J2
Homology/Alignments : Family Browser (UCSC)CYP2J2
Gene fusions - Rearrangements
Fusion : MitelmanNFIA/CYP2J2 [1p31.3/1p32.1]  [t(1;1)(p31;p32)]  
Fusion: TCGANFIA 1p31.3 CYP2J2 1p32.1 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP2J2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP2J2
dbVarCYP2J2
ClinVarCYP2J2
1000_GenomesCYP2J2 
Exome Variant ServerCYP2J2
ExAC (Exome Aggregation Consortium)CYP2J2 (select the gene name)
Genetic variants : HAPMAP1573
Genomic Variants (DGV)CYP2J2 [DGVbeta]
DECIPHER (Syndromes)1:60358980-60392470  ENSG00000134716
CONAN: Copy Number AnalysisCYP2J2 
Mutations
ICGC Data PortalCYP2J2 
TCGA Data PortalCYP2J2 
Broad Tumor PortalCYP2J2
OASIS PortalCYP2J2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP2J2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYP2J2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYP2J2
DgiDB (Drug Gene Interaction Database)CYP2J2
DoCM (Curated mutations)CYP2J2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP2J2 (select a term)
intoGenCYP2J2
Cancer3DCYP2J2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601258   
Orphanet
MedgenCYP2J2
Genetic Testing Registry CYP2J2
NextProtP51589 [Medical]
TSGene1573
GENETestsCYP2J2
Huge Navigator CYP2J2 [HugePedia]
snp3D : Map Gene to Disease1573
BioCentury BCIQCYP2J2
ClinGenCYP2J2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1573
Chemical/Pharm GKB GenePA27112
Clinical trialCYP2J2
Miscellaneous
canSAR (ICR)CYP2J2 (select the gene name)
Probes
Litterature
PubMed91 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP2J2
EVEXCYP2J2
GoPubMedCYP2J2
iHOPCYP2J2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:58:16 CEST 2017

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