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CYP2U1 (cytochrome P450 family 2 subfamily U member 1)

Identity

Alias_namescytochrome P450, family 2, subfamily U, polypeptide 1
Alias_symbol (synonym)SPG49
Other aliasP450TEC
SPG56
HGNC (Hugo) CYP2U1
LocusID (NCBI) 113612
Atlas_Id 62255
Location 4q25  [Link to chromosome band 4q25]
Location_base_pair Starts at 107931561 and ends at 107953457 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP2U1   20582
Cards
Entrez_Gene (NCBI)CYP2U1  113612  cytochrome P450 family 2 subfamily U member 1
AliasesP450TEC; SPG49; SPG56
GeneCards (Weizmann)CYP2U1
Ensembl hg19 (Hinxton)ENSG00000155016 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155016 [Gene_View]  chr4:107931561-107953457 [Contig_View]  CYP2U1 [Vega]
ICGC DataPortalENSG00000155016
TCGA cBioPortalCYP2U1
AceView (NCBI)CYP2U1
Genatlas (Paris)CYP2U1
WikiGenes113612
SOURCE (Princeton)CYP2U1
Genetics Home Reference (NIH)CYP2U1
Genomic and cartography
GoldenPath hg38 (UCSC)CYP2U1  -     chr4:107931561-107953457 +  4q25   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYP2U1  -     4q25   [Description]    (hg19-Feb_2009)
EnsemblCYP2U1 - 4q25 [CytoView hg19]  CYP2U1 - 4q25 [CytoView hg38]
Mapping of homologs : NCBICYP2U1 [Mapview hg19]  CYP2U1 [Mapview hg38]
OMIM610670   615030   
Gene and transcription
Genbank (Entrez)AK026498 AK290002 AK298989 AK303284 AK304724
RefSeq transcript (Entrez)NM_183075
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYP2U1
Cluster EST : UnigeneHs.109087 [ NCBI ]
CGAP (NCI)Hs.109087
Alternative Splicing GalleryENSG00000155016
Gene ExpressionCYP2U1 [ NCBI-GEO ]   CYP2U1 [ EBI - ARRAY_EXPRESS ]   CYP2U1 [ SEEK ]   CYP2U1 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP2U1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)113612
GTEX Portal (Tissue expression)CYP2U1
Human Protein AtlasENSG00000155016-CYP2U1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z449   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z449  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z449
Splice isoforms : SwissVarQ7Z449
PhosPhoSitePlusQ7Z449
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I    Cyt_P450_E_grp-I_CYP2D-like   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP2U1
DMDM Disease mutations113612
Blocks (Seattle)CYP2U1
SuperfamilyQ7Z449
Human Protein Atlas [tissue]ENSG00000155016-CYP2U1 [tissue]
Peptide AtlasQ7Z449
HPRD13109
IPIIPI00783946   IPI00847660   IPI00965432   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z449
IntAct (EBI)Q7Z449
FunCoupENSG00000155016
BioGRIDCYP2U1
STRING (EMBL)CYP2U1
ZODIACCYP2U1
Ontologies - Pathways
QuickGOQ7Z449
Ontology : AmiGOmonooxygenase activity  iron ion binding  endoplasmic reticulum membrane  integral component of membrane  oxygen binding  heme binding  organelle membrane  oxidation-reduction process  aromatase activity  omega-hydroxylase P450 pathway  
Ontology : EGO-EBImonooxygenase activity  iron ion binding  endoplasmic reticulum membrane  integral component of membrane  oxygen binding  heme binding  organelle membrane  oxidation-reduction process  aromatase activity  omega-hydroxylase P450 pathway  
Pathways : KEGGArachidonic acid metabolism   
NDEx NetworkCYP2U1
Atlas of Cancer Signalling NetworkCYP2U1
Wikipedia pathwaysCYP2U1
Orthology - Evolution
OrthoDB113612
GeneTree (enSembl)ENSG00000155016
Phylogenetic Trees/Animal Genes : TreeFamCYP2U1
HOVERGENQ7Z449
HOGENOMQ7Z449
Homologs : HomoloGeneCYP2U1
Homology/Alignments : Family Browser (UCSC)CYP2U1
Gene fusions - Rearrangements
Tumor Fusion PortalCYP2U1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP2U1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP2U1
dbVarCYP2U1
ClinVarCYP2U1
1000_GenomesCYP2U1 
Exome Variant ServerCYP2U1
ExAC (Exome Aggregation Consortium)ENSG00000155016
GNOMAD BrowserENSG00000155016
Genetic variants : HAPMAP113612
Genomic Variants (DGV)CYP2U1 [DGVbeta]
DECIPHERCYP2U1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYP2U1 
Mutations
ICGC Data PortalCYP2U1 
TCGA Data PortalCYP2U1 
Broad Tumor PortalCYP2U1
OASIS PortalCYP2U1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP2U1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYP2U1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYP2U1
DgiDB (Drug Gene Interaction Database)CYP2U1
DoCM (Curated mutations)CYP2U1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP2U1 (select a term)
intoGenCYP2U1
Cancer3DCYP2U1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610670    615030   
Orphanet21723   
DisGeNETCYP2U1
MedgenCYP2U1
Genetic Testing Registry CYP2U1
NextProtQ7Z449 [Medical]
TSGene113612
GENETestsCYP2U1
Target ValidationCYP2U1
Huge Navigator CYP2U1 [HugePedia]
snp3D : Map Gene to Disease113612
BioCentury BCIQCYP2U1
ClinGenCYP2U1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD113612
Chemical/Pharm GKB GenePA134924269
Clinical trialCYP2U1
Miscellaneous
canSAR (ICR)CYP2U1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP2U1
EVEXCYP2U1
GoPubMedCYP2U1
iHOPCYP2U1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:09:46 CET 2017

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