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CYP3A7 (cytochrome P450 family 3 subfamily A member 7)

Identity

Alias_namescytochrome P450, subfamily IIIA, polypeptide 7
cytochrome P450, family 3, subfamily A, polypeptide 7
Alias_symbol (synonym)CP37
P450-HFLA
Other aliasCYPIIIA7
P-450(HFL33)
P-450111A7
HGNC (Hugo) CYP3A7
LocusID (NCBI) 1551
Atlas_Id 52170
Location 7q22.1  [Link to chromosome band 7q22]
Location_base_pair Starts at 99302660 and ends at 99332823 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP3A7   2640
Cards
Entrez_Gene (NCBI)CYP3A7  1551  cytochrome P450 family 3 subfamily A member 7
AliasesCP37; CYPIIIA7; P-450(HFL33); P-450111A7; 
P450-HFLA
GeneCards (Weizmann)CYP3A7
Ensembl hg19 (Hinxton)ENSG00000160870 [Gene_View]  chr7:99302660-99332823 [Contig_View]  CYP3A7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000160870 [Gene_View]  chr7:99302660-99332823 [Contig_View]  CYP3A7 [Vega]
ICGC DataPortalENSG00000160870
TCGA cBioPortalCYP3A7
AceView (NCBI)CYP3A7
Genatlas (Paris)CYP3A7
WikiGenes1551
SOURCE (Princeton)CYP3A7
Genetics Home Reference (NIH)CYP3A7
Genomic and cartography
GoldenPath hg19 (UCSC)CYP3A7  -     chr7:99302660-99332823 -  7q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CYP3A7  -     7q22.1   [Description]    (hg38-Dec_2013)
EnsemblCYP3A7 - 7q22.1 [CytoView hg19]  CYP3A7 - 7q22.1 [CytoView hg38]
Mapping of homologs : NCBICYP3A7 [Mapview hg19]  CYP3A7 [Mapview hg38]
OMIM605340   
Gene and transcription
Genbank (Entrez)BC067436 BC069780 BX643367 BX647143 D00408
RefSeq transcript (Entrez)NM_000765
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_007983 NT_007933 NW_004929332
Consensus coding sequences : CCDS (NCBI)CYP3A7
Cluster EST : UnigeneHs.111944 [ NCBI ]
CGAP (NCI)Hs.111944
Alternative Splicing GalleryENSG00000160870
Gene ExpressionCYP3A7 [ NCBI-GEO ]   CYP3A7 [ EBI - ARRAY_EXPRESS ]   CYP3A7 [ SEEK ]   CYP3A7 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP3A7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1551
GTEX Portal (Tissue expression)CYP3A7
Protein : pattern, domain, 3D structure
UniProt/SwissProtP24462   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP24462  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP24462
Splice isoforms : SwissVarP24462
Catalytic activity : Enzyme1.14.14.1 [ Enzyme-Expasy ]   1.14.14.11.14.14.1 [ IntEnz-EBI ]   1.14.14.1 [ BRENDA ]   1.14.14.1 [ KEGG ]   
PhosPhoSitePlusP24462
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_CYP3A    Cyt_P450_E_grp-II   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP3A7
DMDM Disease mutations1551
Blocks (Seattle)CYP3A7
SuperfamilyP24462
Human Protein AtlasENSG00000160870
Peptide AtlasP24462
HPRD05630
IPIIPI00396632   IPI00164895   
Protein Interaction databases
DIP (DOE-UCLA)P24462
IntAct (EBI)P24462
FunCoupENSG00000160870
BioGRIDCYP3A7
STRING (EMBL)CYP3A7
ZODIACCYP3A7
Ontologies - Pathways
QuickGOP24462
Ontology : AmiGOmonooxygenase activity  iron ion binding  endoplasmic reticulum membrane  xenobiotic metabolic process  oxygen binding  heme binding  oxidation-reduction process  aromatase activity  
Ontology : EGO-EBImonooxygenase activity  iron ion binding  endoplasmic reticulum membrane  xenobiotic metabolic process  oxygen binding  heme binding  oxidation-reduction process  aromatase activity  
Pathways : KEGGSteroid hormone biosynthesis    Retinol metabolism    Chemical carcinogenesis   
NDEx NetworkCYP3A7
Atlas of Cancer Signalling NetworkCYP3A7
Wikipedia pathwaysCYP3A7
Orthology - Evolution
OrthoDB1551
GeneTree (enSembl)ENSG00000160870
Phylogenetic Trees/Animal Genes : TreeFamCYP3A7
HOVERGENP24462
HOGENOMP24462
Homologs : HomoloGeneCYP3A7
Homology/Alignments : Family Browser (UCSC)CYP3A7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP3A7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP3A7
dbVarCYP3A7
ClinVarCYP3A7
1000_GenomesCYP3A7 
Exome Variant ServerCYP3A7
ExAC (Exome Aggregation Consortium)CYP3A7 (select the gene name)
Genetic variants : HAPMAP1551
Genomic Variants (DGV)CYP3A7 [DGVbeta]
DECIPHER (Syndromes)7:99302660-99332823  ENSG00000160870
CONAN: Copy Number AnalysisCYP3A7 
Mutations
ICGC Data PortalCYP3A7 
TCGA Data PortalCYP3A7 
Broad Tumor PortalCYP3A7
OASIS PortalCYP3A7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP3A7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYP3A7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYP3A7
DgiDB (Drug Gene Interaction Database)CYP3A7
DoCM (Curated mutations)CYP3A7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP3A7 (select a term)
intoGenCYP3A7
Cancer3DCYP3A7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605340   
Orphanet
MedgenCYP3A7
Genetic Testing Registry CYP3A7
NextProtP24462 [Medical]
TSGene1551
GENETestsCYP3A7
Huge Navigator CYP3A7 [HugePedia]
snp3D : Map Gene to Disease1551
BioCentury BCIQCYP3A7
ClinGenCYP3A7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1551
Chemical/Pharm GKB GenePA122
Clinical trialCYP3A7
Miscellaneous
canSAR (ICR)CYP3A7 (select the gene name)
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP3A7
EVEXCYP3A7
GoPubMedCYP3A7
iHOPCYP3A7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:02:33 CET 2017

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