Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYP4A22 (cytochrome P450 family 4 subfamily A member 22)

Identity

Alias (NCBI)-
HGNC (Hugo) CYP4A22
HGNC Previous namecytochrome P450, family 4, subfamily A, polypeptide 22
LocusID (NCBI) 284541
Atlas_Id 62258
Location 1p33  [Link to chromosome band 1p33]
Location_base_pair Starts at 47137425 and ends at 47147481 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP4A22   20575
Cards
Entrez_Gene (NCBI)CYP4A22  284541  cytochrome P450 family 4 subfamily A member 22
Aliases
GeneCards (Weizmann)CYP4A22
Ensembl hg19 (Hinxton)ENSG00000162365 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162365 [Gene_View]  ENSG00000162365 [Sequence]  chr1:47137425-47147481 [Contig_View]  CYP4A22 [Vega]
ICGC DataPortalENSG00000162365
TCGA cBioPortalCYP4A22
AceView (NCBI)CYP4A22
Genatlas (Paris)CYP4A22
WikiGenes284541
SOURCE (Princeton)CYP4A22
Genetics Home Reference (NIH)CYP4A22
Genomic and cartography
GoldenPath hg38 (UCSC)CYP4A22  -     chr1:47137425-47147481 +  1p33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYP4A22  -     1p33   [Description]    (hg19-Feb_2009)
GoldenPathCYP4A22 - 1p33 [CytoView hg19]  CYP4A22 - 1p33 [CytoView hg38]
ImmunoBaseENSG00000162365
genome Data Viewer NCBICYP4A22 [Mapview hg19]  
OMIM615341   
Gene and transcription
Genbank (Entrez)AY280371 AY280372 BC142607 BC142690 BC148248
RefSeq transcript (Entrez)NM_001010969 NM_001308102
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYP4A22
Alternative Splicing GalleryENSG00000162365
Gene ExpressionCYP4A22 [ NCBI-GEO ]   CYP4A22 [ EBI - ARRAY_EXPRESS ]   CYP4A22 [ SEEK ]   CYP4A22 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP4A22 [ Firebrowse - Broad ]
GenevisibleExpression of CYP4A22 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284541
GTEX Portal (Tissue expression)CYP4A22
Human Protein AtlasENSG00000162365-CYP4A22 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TCH4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TCH4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TCH4
Splice isoforms : SwissVarQ5TCH4
PhosPhoSitePlusQ5TCH4
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I    Cyt_P450_sf   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP4A22
DMDM Disease mutations284541
Blocks (Seattle)CYP4A22
SuperfamilyQ5TCH4
Human Protein Atlas [tissue]ENSG00000162365-CYP4A22 [tissue]
Peptide AtlasQ5TCH4
HPRD16776
IPIIPI00429358   IPI00647932   IPI00514763   
Protein Interaction databases
DIP (DOE-UCLA)Q5TCH4
IntAct (EBI)Q5TCH4
FunCoupENSG00000162365
BioGRIDCYP4A22
STRING (EMBL)CYP4A22
ZODIACCYP4A22
Ontologies - Pathways
QuickGOQ5TCH4
Ontology : AmiGOlipid hydroxylation  iron ion binding  extracellular space  endoplasmic reticulum membrane  heme binding  arachidonic acid omega-hydroxylase activity  oxidation-reduction process  omega-hydroxylase P450 pathway  laurate hydroxylase activity  16-hydroxypalmitate dehydrogenase activity  
Ontology : EGO-EBIlipid hydroxylation  iron ion binding  extracellular space  endoplasmic reticulum membrane  heme binding  arachidonic acid omega-hydroxylase activity  oxidation-reduction process  omega-hydroxylase P450 pathway  laurate hydroxylase activity  16-hydroxypalmitate dehydrogenase activity  
NDEx NetworkCYP4A22
Atlas of Cancer Signalling NetworkCYP4A22
Wikipedia pathwaysCYP4A22
Orthology - Evolution
OrthoDB284541
GeneTree (enSembl)ENSG00000162365
Phylogenetic Trees/Animal Genes : TreeFamCYP4A22
HOGENOMQ5TCH4
Homologs : HomoloGeneCYP4A22
Homology/Alignments : Family Browser (UCSC)CYP4A22
Gene fusions - Rearrangements
Fusion : QuiverCYP4A22
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP4A22 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP4A22
dbVarCYP4A22
ClinVarCYP4A22
1000_GenomesCYP4A22 
Exome Variant ServerCYP4A22
GNOMAD BrowserENSG00000162365
Varsome BrowserCYP4A22
Genetic variants : HAPMAP284541
Genomic Variants (DGV)CYP4A22 [DGVbeta]
DECIPHERCYP4A22 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYP4A22 
Mutations
ICGC Data PortalCYP4A22 
TCGA Data PortalCYP4A22 
Broad Tumor PortalCYP4A22
OASIS PortalCYP4A22 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP4A22  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCYP4A22
Mutations and Diseases : HGMDCYP4A22
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYP4A22
DgiDB (Drug Gene Interaction Database)CYP4A22
DoCM (Curated mutations)CYP4A22 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP4A22 (select a term)
intoGenCYP4A22
Cancer3DCYP4A22(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615341   
Orphanet
DisGeNETCYP4A22
MedgenCYP4A22
Genetic Testing Registry CYP4A22
NextProtQ5TCH4 [Medical]
TSGene284541
GENETestsCYP4A22
Target ValidationCYP4A22
Huge Navigator CYP4A22 [HugePedia]
snp3D : Map Gene to Disease284541
BioCentury BCIQCYP4A22
ClinGenCYP4A22
Clinical trials, drugs, therapy
Protein Interactions : CTD284541
Pharm GKB GenePA134979692
Clinical trialCYP4A22
Miscellaneous
canSAR (ICR)CYP4A22 (select the gene name)
HarmonizomeCYP4A22
DataMed IndexCYP4A22
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP4A22
EVEXCYP4A22
GoPubMedCYP4A22
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Aug 22 19:09:31 CEST 2020

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