Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYP4F12 (cytochrome P450, family 4, subfamily F, polypeptide 12)

Identity

Alias_namescytochrome P450, subfamily IVF, polypeptide 12
cytochrome P450, family 4, subfamily F, polypeptide 12
Other aliasCYPIVF12
F22329_1
HGNC (Hugo) CYP4F12
LocusID (NCBI) 66002
Atlas_Id 62260
Location 19p13.12  [Link to chromosome band 19p13]
Location_base_pair Starts at 15783828 and ends at 15807984 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DPM1 (20q13.13) / CYP4F12 (19p13.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP4F12   18857
Cards
Entrez_Gene (NCBI)CYP4F12  66002  cytochrome P450, family 4, subfamily F, polypeptide 12
AliasesCYPIVF12; F22329_1
GeneCards (Weizmann)CYP4F12
Ensembl hg19 (Hinxton)ENSG00000186204 [Gene_View]  chr19:15783828-15807984 [Contig_View]  CYP4F12 [Vega]
Ensembl hg38 (Hinxton)ENSG00000186204 [Gene_View]  chr19:15783828-15807984 [Contig_View]  CYP4F12 [Vega]
ICGC DataPortalENSG00000186204
TCGA cBioPortalCYP4F12
AceView (NCBI)CYP4F12
Genatlas (Paris)CYP4F12
WikiGenes66002
SOURCE (Princeton)CYP4F12
Genetics Home Reference (NIH)CYP4F12
Genomic and cartography
GoldenPath hg19 (UCSC)CYP4F12  -     chr19:15783828-15807984 +  19p13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CYP4F12  -     19p13.12   [Description]    (hg38-Dec_2013)
EnsemblCYP4F12 - 19p13.12 [CytoView hg19]  CYP4F12 - 19p13.12 [CytoView hg38]
Mapping of homologs : NCBICYP4F12 [Mapview hg19]  CYP4F12 [Mapview hg38]
OMIM611485   
Gene and transcription
Genbank (Entrez)AB035130 AB035131 AK074412 AK075435 AK304138
RefSeq transcript (Entrez)NM_023944
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_008336 NT_011295 NW_004929414
Consensus coding sequences : CCDS (NCBI)CYP4F12
Cluster EST : UnigeneHs.131459 [ NCBI ]
CGAP (NCI)Hs.131459
Alternative Splicing GalleryENSG00000186204
Gene ExpressionCYP4F12 [ NCBI-GEO ]   CYP4F12 [ EBI - ARRAY_EXPRESS ]   CYP4F12 [ SEEK ]   CYP4F12 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP4F12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)66002
GTEX Portal (Tissue expression)CYP4F12
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCS2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCS2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCS2
Splice isoforms : SwissVarQ9HCS2
Catalytic activity : Enzyme1.14.14.1 [ Enzyme-Expasy ]   1.14.14.11.14.14.1 [ IntEnz-EBI ]   1.14.14.1 [ BRENDA ]   1.14.14.1 [ KEGG ]   
PhosPhoSitePlusQ9HCS2
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP4F12
DMDM Disease mutations66002
Blocks (Seattle)CYP4F12
SuperfamilyQ9HCS2
Human Protein AtlasENSG00000186204
Peptide AtlasQ9HCS2
HPRD07102
IPIIPI00289171   IPI01021964   IPI01022416   IPI01022988   IPI00552747   
Protein Interaction databases
DIP (DOE-UCLA)Q9HCS2
IntAct (EBI)Q9HCS2
FunCoupENSG00000186204
BioGRIDCYP4F12
STRING (EMBL)CYP4F12
ZODIACCYP4F12
Ontologies - Pathways
QuickGOQ9HCS2
Ontology : AmiGOvery long-chain fatty acid metabolic process  long-chain fatty acid metabolic process  renal water homeostasis  pressure natriuresis  iron ion binding  cytoplasm  endoplasmic reticulum membrane  xenobiotic metabolic process  arachidonic acid epoxygenase activity  integral component of membrane  apical plasma membrane  drug metabolic process  alkane 1-monooxygenase activity  arachidonic acid metabolic process  epoxygenase P450 pathway  heme binding  leukotriene B4 catabolic process  vitamin E metabolic process  intracellular membrane-bounded organelle  small molecule metabolic process  leukotriene-B4 20-monooxygenase activity  sodium ion homeostasis  oxidation-reduction process  aromatase activity  
Ontology : EGO-EBIvery long-chain fatty acid metabolic process  long-chain fatty acid metabolic process  renal water homeostasis  pressure natriuresis  iron ion binding  cytoplasm  endoplasmic reticulum membrane  xenobiotic metabolic process  arachidonic acid epoxygenase activity  integral component of membrane  apical plasma membrane  drug metabolic process  alkane 1-monooxygenase activity  arachidonic acid metabolic process  epoxygenase P450 pathway  heme binding  leukotriene B4 catabolic process  vitamin E metabolic process  intracellular membrane-bounded organelle  small molecule metabolic process  leukotriene-B4 20-monooxygenase activity  sodium ion homeostasis  oxidation-reduction process  aromatase activity  
NDEx NetworkCYP4F12
Atlas of Cancer Signalling NetworkCYP4F12
Wikipedia pathwaysCYP4F12
Orthology - Evolution
OrthoDB66002
GeneTree (enSembl)ENSG00000186204
Phylogenetic Trees/Animal Genes : TreeFamCYP4F12
HOVERGENQ9HCS2
HOGENOMQ9HCS2
Homologs : HomoloGeneCYP4F12
Homology/Alignments : Family Browser (UCSC)CYP4F12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP4F12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP4F12
dbVarCYP4F12
ClinVarCYP4F12
1000_GenomesCYP4F12 
Exome Variant ServerCYP4F12
ExAC (Exome Aggregation Consortium)CYP4F12 (select the gene name)
Genetic variants : HAPMAP66002
Genomic Variants (DGV)CYP4F12 [DGVbeta]
DECIPHER (Syndromes)19:15783828-15807984  ENSG00000186204
CONAN: Copy Number AnalysisCYP4F12 
Mutations
ICGC Data PortalCYP4F12 
TCGA Data PortalCYP4F12 
Broad Tumor PortalCYP4F12
OASIS PortalCYP4F12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP4F12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYP4F12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYP4F12
DgiDB (Drug Gene Interaction Database)CYP4F12
DoCM (Curated mutations)CYP4F12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP4F12 (select a term)
intoGenCYP4F12
Cancer3DCYP4F12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611485   
Orphanet
MedgenCYP4F12
Genetic Testing Registry CYP4F12
NextProtQ9HCS2 [Medical]
TSGene66002
GENETestsCYP4F12
Huge Navigator CYP4F12 [HugePedia]
snp3D : Map Gene to Disease66002
BioCentury BCIQCYP4F12
ClinGenCYP4F12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD66002
Chemical/Pharm GKB GenePA38717
Clinical trialCYP4F12
Miscellaneous
canSAR (ICR)CYP4F12 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP4F12
EVEXCYP4F12
GoPubMedCYP4F12
iHOPCYP4F12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:00:54 CET 2017

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