Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CYP4F2 (cytochrome P450 family 4 subfamily F member 2)

Identity

Alias_namescytochrome P450, subfamily IVF, polypeptide 2
cytochrome P450, family 4, subfamily F, polypeptide 2
Other aliasCPF2
HGNC (Hugo) CYP4F2
LocusID (NCBI) 8529
Atlas_Id 54891
Location 19p13.12  [Link to chromosome band 19p13]
Location_base_pair Starts at 15878024 and ends at 15898120 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP4F2   2645
Cards
Entrez_Gene (NCBI)CYP4F2  8529  cytochrome P450 family 4 subfamily F member 2
AliasesCPF2
GeneCards (Weizmann)CYP4F2
Ensembl hg19 (Hinxton)ENSG00000186115 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186115 [Gene_View]  chr19:15878024-15898120 [Contig_View]  CYP4F2 [Vega]
ICGC DataPortalENSG00000186115
TCGA cBioPortalCYP4F2
AceView (NCBI)CYP4F2
Genatlas (Paris)CYP4F2
WikiGenes8529
SOURCE (Princeton)CYP4F2
Genetics Home Reference (NIH)CYP4F2
Genomic and cartography
GoldenPath hg38 (UCSC)CYP4F2  -     chr19:15878024-15898120 -  19p13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYP4F2  -     19p13.12   [Description]    (hg19-Feb_2009)
EnsemblCYP4F2 - 19p13.12 [CytoView hg19]  CYP4F2 - 19p13.12 [CytoView hg38]
Mapping of homologs : NCBICYP4F2 [Mapview hg19]  CYP4F2 [Mapview hg38]
OMIM604426   
Gene and transcription
Genbank (Entrez)AK290790 AK296200 AK300961 AK313705 BC067437
RefSeq transcript (Entrez)NM_001082
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYP4F2
Cluster EST : UnigeneHs.558423 [ NCBI ]
CGAP (NCI)Hs.558423
Alternative Splicing GalleryENSG00000186115
Gene ExpressionCYP4F2 [ NCBI-GEO ]   CYP4F2 [ EBI - ARRAY_EXPRESS ]   CYP4F2 [ SEEK ]   CYP4F2 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP4F2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8529
GTEX Portal (Tissue expression)CYP4F2
Human Protein AtlasENSG00000186115-CYP4F2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78329   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP78329  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP78329
Splice isoforms : SwissVarP78329
PhosPhoSitePlusP78329
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP4F2
DMDM Disease mutations8529
Blocks (Seattle)CYP4F2
SuperfamilyP78329
Human Protein Atlas [tissue]ENSG00000186115-CYP4F2 [tissue]
Peptide AtlasP78329
HPRD05112
IPIIPI00298792   
Protein Interaction databases
DIP (DOE-UCLA)P78329
IntAct (EBI)P78329
FunCoupENSG00000186115
BioGRIDCYP4F2
STRING (EMBL)CYP4F2
ZODIACCYP4F2
Ontologies - Pathways
QuickGOP78329
Ontology : AmiGOvery long-chain fatty acid metabolic process  long-chain fatty acid metabolic process  renal water homeostasis  pressure natriuresis  monooxygenase activity  iron ion binding  protein binding  cytoplasm  endoplasmic reticulum membrane  icosanoid metabolic process  leukotriene metabolic process  blood coagulation  regulation of blood pressure  arachidonic acid epoxygenase activity  apical plasma membrane  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen  drug metabolic process  alkane 1-monooxygenase activity  arachidonic acid metabolic process  epoxygenase P450 pathway  heme binding  organelle membrane  negative regulation of icosanoid secretion  positive regulation of icosanoid secretion  leukotriene B4 catabolic process  vitamin E metabolic process  menaquinone catabolic process  phylloquinone catabolic process  phylloquinone catabolic process  vitamin K catabolic process  intracellular membrane-bounded organelle  leukotriene-B4 20-monooxygenase activity  leukotriene-B4 20-monooxygenase activity  arachidonic acid omega-hydroxylase activity  alpha-tocopherol omega-hydroxylase activity  tocotrienol omega-hydroxylase activity  sodium ion homeostasis  oxidation-reduction process  20-hydroxy-leukotriene B4 omega oxidase activity  20-aldehyde-leukotriene B4 20-monooxygenase activity  omega-hydroxylase P450 pathway  
Ontology : EGO-EBIvery long-chain fatty acid metabolic process  long-chain fatty acid metabolic process  renal water homeostasis  pressure natriuresis  monooxygenase activity  iron ion binding  protein binding  cytoplasm  endoplasmic reticulum membrane  icosanoid metabolic process  leukotriene metabolic process  blood coagulation  regulation of blood pressure  arachidonic acid epoxygenase activity  apical plasma membrane  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen  drug metabolic process  alkane 1-monooxygenase activity  arachidonic acid metabolic process  epoxygenase P450 pathway  heme binding  organelle membrane  negative regulation of icosanoid secretion  positive regulation of icosanoid secretion  leukotriene B4 catabolic process  vitamin E metabolic process  menaquinone catabolic process  phylloquinone catabolic process  phylloquinone catabolic process  vitamin K catabolic process  intracellular membrane-bounded organelle  leukotriene-B4 20-monooxygenase activity  leukotriene-B4 20-monooxygenase activity  arachidonic acid omega-hydroxylase activity  alpha-tocopherol omega-hydroxylase activity  tocotrienol omega-hydroxylase activity  sodium ion homeostasis  oxidation-reduction process  20-hydroxy-leukotriene B4 omega oxidase activity  20-aldehyde-leukotriene B4 20-monooxygenase activity  omega-hydroxylase P450 pathway  
Pathways : KEGGArachidonic acid metabolism   
NDEx NetworkCYP4F2
Atlas of Cancer Signalling NetworkCYP4F2
Wikipedia pathwaysCYP4F2
Orthology - Evolution
OrthoDB8529
GeneTree (enSembl)ENSG00000186115
Phylogenetic Trees/Animal Genes : TreeFamCYP4F2
HOVERGENP78329
HOGENOMP78329
Homologs : HomoloGeneCYP4F2
Homology/Alignments : Family Browser (UCSC)CYP4F2
Gene fusions - Rearrangements
Fusion: Tumor Portal CYP4F2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP4F2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP4F2
dbVarCYP4F2
ClinVarCYP4F2
1000_GenomesCYP4F2 
Exome Variant ServerCYP4F2
ExAC (Exome Aggregation Consortium)ENSG00000186115
GNOMAD BrowserENSG00000186115
Genetic variants : HAPMAP8529
Genomic Variants (DGV)CYP4F2 [DGVbeta]
DECIPHERCYP4F2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYP4F2 
Mutations
ICGC Data PortalCYP4F2 
TCGA Data PortalCYP4F2 
Broad Tumor PortalCYP4F2
OASIS PortalCYP4F2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP4F2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYP4F2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYP4F2
DgiDB (Drug Gene Interaction Database)CYP4F2
DoCM (Curated mutations)CYP4F2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP4F2 (select a term)
intoGenCYP4F2
Cancer3DCYP4F2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604426   
Orphanet23060   
MedgenCYP4F2
Genetic Testing Registry CYP4F2
NextProtP78329 [Medical]
TSGene8529
GENETestsCYP4F2
Target ValidationCYP4F2
Huge Navigator CYP4F2 [HugePedia]
snp3D : Map Gene to Disease8529
BioCentury BCIQCYP4F2
ClinGenCYP4F2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8529
Chemical/Pharm GKB GenePA27121
Clinical trialCYP4F2
Miscellaneous
canSAR (ICR)CYP4F2 (select the gene name)
Probes
Litterature
PubMed117 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP4F2
EVEXCYP4F2
GoPubMedCYP4F2
iHOPCYP4F2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:46:42 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.