Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYP4F3 (cytochrome P450 family 4 subfamily F member 3)

Identity

Alias_namesLTB4H
cytochrome P450, subfamily IVF, polypeptide 3 (leukotriene B4 omega hydroxylase)
cytochrome P450, family 4, subfamily F, polypeptide 3
Alias_symbol (synonym)CYP4F
Other aliasCPF3
HGNC (Hugo) CYP4F3
LocusID (NCBI) 4051
Atlas_Id 50797
Location 19p13.12  [Link to chromosome band 19p13]
Location_base_pair Starts at 15751707 and ends at 15771570 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GRIN2B (12p13.1) / CYP4F3 (19p13.12)WIZ (19p13.12) / CYP4F3 (19p13.12)WIZ 19p13.12 / CYP4F3 19p13.12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP4F3   2646
Cards
Entrez_Gene (NCBI)CYP4F3  4051  cytochrome P450 family 4 subfamily F member 3
AliasesCPF3; CYP4F; LTB4H
GeneCards (Weizmann)CYP4F3
Ensembl hg19 (Hinxton)ENSG00000186529 [Gene_View]  chr19:15751707-15771570 [Contig_View]  CYP4F3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000186529 [Gene_View]  chr19:15751707-15771570 [Contig_View]  CYP4F3 [Vega]
ICGC DataPortalENSG00000186529
TCGA cBioPortalCYP4F3
AceView (NCBI)CYP4F3
Genatlas (Paris)CYP4F3
WikiGenes4051
SOURCE (Princeton)CYP4F3
Genetics Home Reference (NIH)CYP4F3
Genomic and cartography
GoldenPath hg19 (UCSC)CYP4F3  -     chr19:15751707-15771570 +  19p13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CYP4F3  -     19p13.12   [Description]    (hg38-Dec_2013)
EnsemblCYP4F3 - 19p13.12 [CytoView hg19]  CYP4F3 - 19p13.12 [CytoView hg38]
Mapping of homologs : NCBICYP4F3 [Mapview hg19]  CYP4F3 [Mapview hg38]
OMIM601270   
Gene and transcription
Genbank (Entrez)AB002454 AF054821 AK296761 AK296802 AK298675
RefSeq transcript (Entrez)NM_000896 NM_001199208 NM_001199209
RefSeq genomic (Entrez)NC_000019 NC_018930 NG_007964 NT_011295 NW_004929414
Consensus coding sequences : CCDS (NCBI)CYP4F3
Cluster EST : UnigeneHs.106242 [ NCBI ]
CGAP (NCI)Hs.106242
Alternative Splicing GalleryENSG00000186529
Gene ExpressionCYP4F3 [ NCBI-GEO ]   CYP4F3 [ EBI - ARRAY_EXPRESS ]   CYP4F3 [ SEEK ]   CYP4F3 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP4F3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4051
GTEX Portal (Tissue expression)CYP4F3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ08477   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ08477  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ08477
Splice isoforms : SwissVarQ08477
PhosPhoSitePlusQ08477
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP4F3
DMDM Disease mutations4051
Blocks (Seattle)CYP4F3
SuperfamilyQ08477
Human Protein AtlasENSG00000186529
Peptide AtlasQ08477
HPRD03169
IPIIPI00002370   
Protein Interaction databases
DIP (DOE-UCLA)Q08477
IntAct (EBI)Q08477
FunCoupENSG00000186529
BioGRIDCYP4F3
STRING (EMBL)CYP4F3
ZODIACCYP4F3
Ontologies - Pathways
QuickGOQ08477
Ontology : AmiGOmonooxygenase activity  iron ion binding  endoplasmic reticulum membrane  icosanoid metabolic process  leukotriene metabolic process  integral component of membrane  oxygen binding  heme binding  leukotriene B4 catabolic process  leukotriene B4 catabolic process  leukotriene-B4 20-monooxygenase activity  alpha-tocopherol omega-hydroxylase activity  oxidation-reduction process  20-hydroxy-leukotriene B4 omega oxidase activity  20-aldehyde-leukotriene B4 20-monooxygenase activity  
Ontology : EGO-EBImonooxygenase activity  iron ion binding  endoplasmic reticulum membrane  icosanoid metabolic process  leukotriene metabolic process  integral component of membrane  oxygen binding  heme binding  leukotriene B4 catabolic process  leukotriene B4 catabolic process  leukotriene-B4 20-monooxygenase activity  alpha-tocopherol omega-hydroxylase activity  oxidation-reduction process  20-hydroxy-leukotriene B4 omega oxidase activity  20-aldehyde-leukotriene B4 20-monooxygenase activity  
Pathways : KEGGArachidonic acid metabolism   
NDEx NetworkCYP4F3
Atlas of Cancer Signalling NetworkCYP4F3
Wikipedia pathwaysCYP4F3
Orthology - Evolution
OrthoDB4051
GeneTree (enSembl)ENSG00000186529
Phylogenetic Trees/Animal Genes : TreeFamCYP4F3
HOVERGENQ08477
HOGENOMQ08477
Homologs : HomoloGeneCYP4F3
Homology/Alignments : Family Browser (UCSC)CYP4F3
Gene fusions - Rearrangements
Fusion : MitelmanGRIN2B/CYP4F3 [12p13.1/19p13.12]  [t(12;19)(p13;p13)]  
Fusion : MitelmanWIZ/CYP4F3 [19p13.12/19p13.12]  [t(19;19)(p13;p13)]  
Fusion: TCGAWIZ 19p13.12 CYP4F3 19p13.12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP4F3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP4F3
dbVarCYP4F3
ClinVarCYP4F3
1000_GenomesCYP4F3 
Exome Variant ServerCYP4F3
ExAC (Exome Aggregation Consortium)CYP4F3 (select the gene name)
Genetic variants : HAPMAP4051
Genomic Variants (DGV)CYP4F3 [DGVbeta]
DECIPHER (Syndromes)19:15751707-15771570  ENSG00000186529
CONAN: Copy Number AnalysisCYP4F3 
Mutations
ICGC Data PortalCYP4F3 
TCGA Data PortalCYP4F3 
Broad Tumor PortalCYP4F3
OASIS PortalCYP4F3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP4F3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYP4F3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYP4F3
DgiDB (Drug Gene Interaction Database)CYP4F3
DoCM (Curated mutations)CYP4F3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP4F3 (select a term)
intoGenCYP4F3
Cancer3DCYP4F3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601270   
Orphanet
MedgenCYP4F3
Genetic Testing Registry CYP4F3
NextProtQ08477 [Medical]
TSGene4051
GENETestsCYP4F3
Huge Navigator CYP4F3 [HugePedia]
snp3D : Map Gene to Disease4051
BioCentury BCIQCYP4F3
ClinGenCYP4F3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4051
Chemical/Pharm GKB GenePA234
Clinical trialCYP4F3
Miscellaneous
canSAR (ICR)CYP4F3 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP4F3
EVEXCYP4F3
GoPubMedCYP4F3
iHOPCYP4F3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 14:58:18 CEST 2017

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