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CYP4F8 (cytochrome P450 family 4 subfamily F member 8)

Identity

Alias_namescytochrome P450, subfamily IVF, polypeptide 8
cytochrome P450, family 4, subfamily F, polypeptide 8
Other aliasCPF8
CYPIVF8
HGNC (Hugo) CYP4F8
LocusID (NCBI) 11283
Atlas_Id 52257
Location 19p13.12  [Link to chromosome band 19p13]
Location_base_pair Starts at 15615218 and ends at 15629637 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BCL2L2-PABPN1 (14q11.2) / CYP4F8 (19p13.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP4F8   2648
Cards
Entrez_Gene (NCBI)CYP4F8  11283  cytochrome P450 family 4 subfamily F member 8
AliasesCPF8; CYPIVF8
GeneCards (Weizmann)CYP4F8
Ensembl hg19 (Hinxton)ENSG00000186526 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186526 [Gene_View]  chr19:15615218-15629637 [Contig_View]  CYP4F8 [Vega]
ICGC DataPortalENSG00000186526
TCGA cBioPortalCYP4F8
AceView (NCBI)CYP4F8
Genatlas (Paris)CYP4F8
WikiGenes11283
SOURCE (Princeton)CYP4F8
Genetics Home Reference (NIH)CYP4F8
Genomic and cartography
GoldenPath hg38 (UCSC)CYP4F8  -     chr19:15615218-15629637 +  19p13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYP4F8  -     19p13.12   [Description]    (hg19-Feb_2009)
EnsemblCYP4F8 - 19p13.12 [CytoView hg19]  CYP4F8 - 19p13.12 [CytoView hg38]
Mapping of homologs : NCBICYP4F8 [Mapview hg19]  CYP4F8 [Mapview hg38]
OMIM611545   
Gene and transcription
Genbank (Entrez)AF133298 AI401776 AK092612 AK096809 AK300478
RefSeq transcript (Entrez)NM_007253
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYP4F8
Cluster EST : UnigeneHs.268554 [ NCBI ]
CGAP (NCI)Hs.268554
Alternative Splicing GalleryENSG00000186526
Gene ExpressionCYP4F8 [ NCBI-GEO ]   CYP4F8 [ EBI - ARRAY_EXPRESS ]   CYP4F8 [ SEEK ]   CYP4F8 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP4F8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11283
GTEX Portal (Tissue expression)CYP4F8
Protein : pattern, domain, 3D structure
UniProt/SwissProtP98187   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP98187  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP98187
Splice isoforms : SwissVarP98187
Catalytic activity : Enzyme1.14.14.1 [ Enzyme-Expasy ]   1.14.14.11.14.14.1 [ IntEnz-EBI ]   1.14.14.1 [ BRENDA ]   1.14.14.1 [ KEGG ]   
PhosPhoSitePlusP98187
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_E_grp-I   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP4F8
DMDM Disease mutations11283
Blocks (Seattle)CYP4F8
SuperfamilyP98187
Human Protein AtlasENSG00000186526
Peptide AtlasP98187
HPRD08518
IPIIPI00024332   IPI00910702   IPI00909136   IPI01009297   
Protein Interaction databases
DIP (DOE-UCLA)P98187
IntAct (EBI)P98187
FunCoupENSG00000186526
BioGRIDCYP4F8
STRING (EMBL)CYP4F8
ZODIACCYP4F8
Ontologies - Pathways
QuickGOP98187
Ontology : AmiGOiron ion binding  endoplasmic reticulum membrane  icosanoid metabolic process  prostaglandin metabolic process  integral component of membrane  alkane 1-monooxygenase activity  oxygen binding  heme binding  organelle membrane  oxidation-reduction process  aromatase activity  
Ontology : EGO-EBIiron ion binding  endoplasmic reticulum membrane  icosanoid metabolic process  prostaglandin metabolic process  integral component of membrane  alkane 1-monooxygenase activity  oxygen binding  heme binding  organelle membrane  oxidation-reduction process  aromatase activity  
Pathways : KEGGArachidonic acid metabolism   
NDEx NetworkCYP4F8
Atlas of Cancer Signalling NetworkCYP4F8
Wikipedia pathwaysCYP4F8
Orthology - Evolution
OrthoDB11283
GeneTree (enSembl)ENSG00000186526
Phylogenetic Trees/Animal Genes : TreeFamCYP4F8
HOVERGENP98187
HOGENOMP98187
Homologs : HomoloGeneCYP4F8
Homology/Alignments : Family Browser (UCSC)CYP4F8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP4F8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP4F8
dbVarCYP4F8
ClinVarCYP4F8
1000_GenomesCYP4F8 
Exome Variant ServerCYP4F8
ExAC (Exome Aggregation Consortium)CYP4F8 (select the gene name)
Genetic variants : HAPMAP11283
Genomic Variants (DGV)CYP4F8 [DGVbeta]
DECIPHERCYP4F8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYP4F8 
Mutations
ICGC Data PortalCYP4F8 
TCGA Data PortalCYP4F8 
Broad Tumor PortalCYP4F8
OASIS PortalCYP4F8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP4F8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYP4F8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYP4F8
DgiDB (Drug Gene Interaction Database)CYP4F8
DoCM (Curated mutations)CYP4F8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP4F8 (select a term)
intoGenCYP4F8
Cancer3DCYP4F8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611545   
Orphanet
MedgenCYP4F8
Genetic Testing Registry CYP4F8
NextProtP98187 [Medical]
TSGene11283
GENETestsCYP4F8
Target ValidationCYP4F8
Huge Navigator CYP4F8 [HugePedia]
snp3D : Map Gene to Disease11283
BioCentury BCIQCYP4F8
ClinGenCYP4F8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11283
Chemical/Pharm GKB GenePA405
Clinical trialCYP4F8
Miscellaneous
canSAR (ICR)CYP4F8 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP4F8
EVEXCYP4F8
GoPubMedCYP4F8
iHOPCYP4F8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:30:27 CEST 2017

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