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CYREN (cell cycle regulator of NHEJ)

Identity

Alias_symbol (synonym)MGC5242
FLJ27285
FLJ22450
MRI
Other aliasC7orf49
MRI-2
HGNC (Hugo) CYREN
LocusID (NCBI) 78996
Atlas_Id 56116
Location 7q33  [Link to chromosome band 7q33]
Location_base_pair Starts at 135165780 and ends at 135170826 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)CYREN   22432
Cards
Entrez_Gene (NCBI)CYREN  78996  cell cycle regulator of NHEJ
AliasesC7orf49; MRI; MRI-2
GeneCards (Weizmann)CYREN
Ensembl hg19 (Hinxton)ENSG00000122783 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122783 [Gene_View]  ENSG00000122783 [Sequence]  chr7:135165780-135170826 [Contig_View]  CYREN [Vega]
ICGC DataPortalENSG00000122783
TCGA cBioPortalCYREN
AceView (NCBI)CYREN
Genatlas (Paris)CYREN
WikiGenes78996
SOURCE (Princeton)CYREN
Genetics Home Reference (NIH)CYREN
Genomic and cartography
GoldenPath hg38 (UCSC)CYREN  -     chr7:135165780-135170826 -  7q33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYREN  -     7q33   [Description]    (hg19-Feb_2009)
EnsemblCYREN - 7q33 [CytoView hg19]  CYREN - 7q33 [CytoView hg38]
Mapping of homologs : NCBICYREN [Mapview hg19]  CYREN [Mapview hg38]
OMIM616980   
Gene and transcription
Genbank (Entrez)AI335567 AI632984 AK026103 AK130795 AL708733
RefSeq transcript (Entrez)NM_001243749 NM_001243751 NM_001243752 NM_001243753 NM_001243754 NM_001243755 NM_001305629 NM_001305630 NM_001363329 NM_001363330 NM_024033
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYREN
Cluster EST : UnigeneHs.744954 [ NCBI ]
CGAP (NCI)Hs.744954
Alternative Splicing GalleryENSG00000122783
Gene ExpressionCYREN [ NCBI-GEO ]   CYREN [ EBI - ARRAY_EXPRESS ]   CYREN [ SEEK ]   CYREN [ MEM ]
Gene Expression Viewer (FireBrowse)CYREN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)78996
GTEX Portal (Tissue expression)CYREN
Human Protein AtlasENSG00000122783-CYREN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BWK5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BWK5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BWK5
Splice isoforms : SwissVarQ9BWK5
PhosPhoSitePlusQ9BWK5
Domains : Interpro (EBI)MRI   
Domain families : Pfam (Sanger)MRI (PF15325)   
Domain families : Pfam (NCBI)pfam15325   
Conserved Domain (NCBI)CYREN
DMDM Disease mutations78996
Blocks (Seattle)CYREN
SuperfamilyQ9BWK5
Human Protein Atlas [tissue]ENSG00000122783-CYREN [tissue]
Peptide AtlasQ9BWK5
HPRD08333
IPIIPI00031497   IPI00884895   IPI00884968   IPI00942066   
Protein Interaction databases
DIP (DOE-UCLA)Q9BWK5
IntAct (EBI)Q9BWK5
FunCoupENSG00000122783
BioGRIDCYREN
STRING (EMBL)CYREN
ZODIACCYREN
Ontologies - Pathways
QuickGOQ9BWK5
Ontology : AmiGOprotein binding  nucleus  nucleus  cytoplasm  cytoplasm  double-strand break repair via nonhomologous end joining  double-strand break repair via nonhomologous end joining  negative regulation of double-strand break repair via nonhomologous end joining  
Ontology : EGO-EBIprotein binding  nucleus  nucleus  cytoplasm  cytoplasm  double-strand break repair via nonhomologous end joining  double-strand break repair via nonhomologous end joining  negative regulation of double-strand break repair via nonhomologous end joining  
NDEx NetworkCYREN
Atlas of Cancer Signalling NetworkCYREN
Wikipedia pathwaysCYREN
Orthology - Evolution
OrthoDB78996
GeneTree (enSembl)ENSG00000122783
Phylogenetic Trees/Animal Genes : TreeFamCYREN
HOVERGENQ9BWK5
HOGENOMQ9BWK5
Homologs : HomoloGeneCYREN
Homology/Alignments : Family Browser (UCSC)CYREN
Gene fusions - Rearrangements
Fusion : QuiverCYREN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYREN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYREN
dbVarCYREN
ClinVarCYREN
1000_GenomesCYREN 
Exome Variant ServerCYREN
ExAC (Exome Aggregation Consortium)ENSG00000122783
GNOMAD BrowserENSG00000122783
Varsome BrowserCYREN
Genetic variants : HAPMAP78996
Genomic Variants (DGV)CYREN [DGVbeta]
DECIPHERCYREN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYREN 
Mutations
ICGC Data PortalCYREN 
TCGA Data PortalCYREN 
Broad Tumor PortalCYREN
OASIS PortalCYREN [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCYREN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYREN
DgiDB (Drug Gene Interaction Database)CYREN
DoCM (Curated mutations)CYREN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYREN (select a term)
intoGenCYREN
Cancer3DCYREN(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616980   
Orphanet
DisGeNETCYREN
MedgenCYREN
Genetic Testing Registry CYREN
NextProtQ9BWK5 [Medical]
TSGene78996
GENETestsCYREN
Target ValidationCYREN
Huge Navigator CYREN [HugePedia]
snp3D : Map Gene to Disease78996
BioCentury BCIQCYREN
ClinGenCYREN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD78996
Chemical/Pharm GKB GenePA162380533
Clinical trialCYREN
Miscellaneous
canSAR (ICR)CYREN (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYREN
EVEXCYREN
GoPubMedCYREN
iHOPCYREN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:01:25 CET 2018

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