Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CYSLTR1 (cysteinyl leukotriene receptor 1)

Identity

Alias_symbol (synonym)CysLT1
CysLT(1)
CYSLT1R
Other aliasCYSLT1
CYSLTR
HMTMF81
HGNC (Hugo) CYSLTR1
LocusID (NCBI) 10800
Atlas_Id 46481
Location Xq21.1  [Link to chromosome band Xq21]
Location_base_pair Starts at 78271472 and ends at 78327691 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CYSLTR1   17451
Cards
Entrez_Gene (NCBI)CYSLTR1  10800  cysteinyl leukotriene receptor 1
AliasesCYSLT1; CYSLT1R; CYSLTR; HMTMF81
GeneCards (Weizmann)CYSLTR1
Ensembl hg19 (Hinxton)ENSG00000173198 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173198 [Gene_View]  ENSG00000173198 [Sequence]  chrX:78271472-78327691 [Contig_View]  CYSLTR1 [Vega]
ICGC DataPortalENSG00000173198
TCGA cBioPortalCYSLTR1
AceView (NCBI)CYSLTR1
Genatlas (Paris)CYSLTR1
WikiGenes10800
SOURCE (Princeton)CYSLTR1
Genetics Home Reference (NIH)CYSLTR1
Genomic and cartography
GoldenPath hg38 (UCSC)CYSLTR1  -     chrX:78271472-78327691 -  Xq21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYSLTR1  -     Xq21.1   [Description]    (hg19-Feb_2009)
EnsemblCYSLTR1 - Xq21.1 [CytoView hg19]  CYSLTR1 - Xq21.1 [CytoView hg38]
Mapping of homologs : NCBICYSLTR1 [Mapview hg19]  CYSLTR1 [Mapview hg38]
OMIM300201   
Gene and transcription
Genbank (Entrez)AF119711 AF133266 AK023929 AK313643 BC035750
RefSeq transcript (Entrez)NM_001282186 NM_001282187 NM_001282188 NM_006639
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYSLTR1
Cluster EST : UnigeneHs.733809 [ NCBI ]
CGAP (NCI)Hs.733809
Alternative Splicing GalleryENSG00000173198
Gene ExpressionCYSLTR1 [ NCBI-GEO ]   CYSLTR1 [ EBI - ARRAY_EXPRESS ]   CYSLTR1 [ SEEK ]   CYSLTR1 [ MEM ]
Gene Expression Viewer (FireBrowse)CYSLTR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10800
GTEX Portal (Tissue expression)CYSLTR1
Human Protein AtlasENSG00000173198-CYSLTR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y271   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y271  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y271
Splice isoforms : SwissVarQ9Y271
PhosPhoSitePlusQ9Y271
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)CLT1_recept    Cyst_leuk_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)CYSLTR1
DMDM Disease mutations10800
Blocks (Seattle)CYSLTR1
SuperfamilyQ9Y271
Human Protein Atlas [tissue]ENSG00000173198-CYSLTR1 [tissue]
Peptide AtlasQ9Y271
HPRD02188
IPIIPI00009080   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y271
IntAct (EBI)Q9Y271
FunCoupENSG00000173198
BioGRIDCYSLTR1
STRING (EMBL)CYSLTR1
ZODIACCYSLTR1
Ontologies - Pathways
QuickGOQ9Y271
Ontology : AmiGOcysteinyl leukotriene receptor activity  inflammatory response to antigenic stimulus  galanin receptor activity  leukotriene receptor activity  protein binding  plasma membrane  integral component of plasma membrane  calcium ion transport  chemotaxis  defense response  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  respiratory gaseous exchange  G-protein coupled peptide receptor activity  membrane  leukotriene signaling pathway  
Ontology : EGO-EBIcysteinyl leukotriene receptor activity  inflammatory response to antigenic stimulus  galanin receptor activity  leukotriene receptor activity  protein binding  plasma membrane  integral component of plasma membrane  calcium ion transport  chemotaxis  defense response  cell surface receptor signaling pathway  G-protein coupled receptor signaling pathway  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  neuropeptide signaling pathway  respiratory gaseous exchange  G-protein coupled peptide receptor activity  membrane  leukotriene signaling pathway  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction   
NDEx NetworkCYSLTR1
Atlas of Cancer Signalling NetworkCYSLTR1
Wikipedia pathwaysCYSLTR1
Orthology - Evolution
OrthoDB10800
GeneTree (enSembl)ENSG00000173198
Phylogenetic Trees/Animal Genes : TreeFamCYSLTR1
HOVERGENQ9Y271
HOGENOMQ9Y271
Homologs : HomoloGeneCYSLTR1
Homology/Alignments : Family Browser (UCSC)CYSLTR1
Gene fusions - Rearrangements
Fusion : QuiverCYSLTR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYSLTR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYSLTR1
dbVarCYSLTR1
ClinVarCYSLTR1
1000_GenomesCYSLTR1 
Exome Variant ServerCYSLTR1
ExAC (Exome Aggregation Consortium)ENSG00000173198
GNOMAD BrowserENSG00000173198
Varsome BrowserCYSLTR1
Genetic variants : HAPMAP10800
Genomic Variants (DGV)CYSLTR1 [DGVbeta]
DECIPHERCYSLTR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYSLTR1 
Mutations
ICGC Data PortalCYSLTR1 
TCGA Data PortalCYSLTR1 
Broad Tumor PortalCYSLTR1
OASIS PortalCYSLTR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYSLTR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYSLTR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch CYSLTR1
DgiDB (Drug Gene Interaction Database)CYSLTR1
DoCM (Curated mutations)CYSLTR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYSLTR1 (select a term)
intoGenCYSLTR1
Cancer3DCYSLTR1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300201   
Orphanet
DisGeNETCYSLTR1
MedgenCYSLTR1
Genetic Testing Registry CYSLTR1
NextProtQ9Y271 [Medical]
TSGene10800
GENETestsCYSLTR1
Target ValidationCYSLTR1
Huge Navigator CYSLTR1 [HugePedia]
snp3D : Map Gene to Disease10800
BioCentury BCIQCYSLTR1
ClinGenCYSLTR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10800
Chemical/Pharm GKB GenePA38453
Clinical trialCYSLTR1
Miscellaneous
canSAR (ICR)CYSLTR1 (select the gene name)
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYSLTR1
EVEXCYSLTR1
GoPubMedCYSLTR1
iHOPCYSLTR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:18:17 CEST 2018
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