Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYSLTR2 (cysteinyl leukotriene receptor 2)

Identity

Alias (NCBI)CYSLT2
CYSLT2R
GPCR21
HG57
HPN321
KPG_011
PSEC0146
hGPCR21
HGNC (Hugo) CYSLTR2
HGNC Alias symbCysLT(2)
CYSLT2R
LocusID (NCBI) 57105
Atlas_Id 52856
Location 13q14.2  [Link to chromosome band 13q14]
Location_base_pair Starts at 48653929 and ends at 48711225 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CYSLTR2 (13q14.2) / ARMCX4 (Xq22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)CYSLTR2   18274
Cards
Entrez_Gene (NCBI)CYSLTR2    cysteinyl leukotriene receptor 2
AliasesCYSLT2; CYSLT2R; GPCR21; HG57; 
HPN321; KPG_011; PSEC0146; hGPCR21
GeneCards (Weizmann)CYSLTR2
Ensembl hg19 (Hinxton)ENSG00000152207 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000152207 [Gene_View]  ENSG00000152207 [Sequence]  chr13:48653929-48711225 [Contig_View]  CYSLTR2 [Vega]
ICGC DataPortalENSG00000152207
TCGA cBioPortalCYSLTR2
AceView (NCBI)CYSLTR2
Genatlas (Paris)CYSLTR2
SOURCE (Princeton)CYSLTR2
Genetics Home Reference (NIH)CYSLTR2
Genomic and cartography
GoldenPath hg38 (UCSC)CYSLTR2  -     chr13:48653929-48711225 +  13q14.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYSLTR2  -     13q14.2   [Description]    (hg19-Feb_2009)
GoldenPathCYSLTR2 - 13q14.2 [CytoView hg19]  CYSLTR2 - 13q14.2 [CytoView hg38]
ImmunoBaseENSG00000152207
genome Data Viewer NCBICYSLTR2 [Mapview hg19]  
OMIM605666   
Gene and transcription
Genbank (Entrez)AB038269 AB041947 AK291739 AY853711 BC069160
RefSeq transcript (Entrez)NM_001308465 NM_001308467 NM_001308468 NM_001308469 NM_001308470 NM_001308471 NM_001308476 NM_001387012 NM_001387013 NM_001387014 NM_020377
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYSLTR2
Alternative Splicing GalleryENSG00000152207
Gene ExpressionCYSLTR2 [ NCBI-GEO ]   CYSLTR2 [ EBI - ARRAY_EXPRESS ]   CYSLTR2 [ SEEK ]   CYSLTR2 [ MEM ]
Gene Expression Viewer (FireBrowse)CYSLTR2 [ Firebrowse - Broad ]
GenevisibleExpression of CYSLTR2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57105
GTEX Portal (Tissue expression)CYSLTR2
Human Protein AtlasENSG00000152207-CYSLTR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS75   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS75  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS75
Splice isoforms : SwissVarQ9NS75
PhosPhoSitePlusQ9NS75
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)CLT2_recept    Cyst_leuk_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)CYSLTR2
Blocks (Seattle)CYSLTR2
SuperfamilyQ9NS75
Human Protein Atlas [tissue]ENSG00000152207-CYSLTR2 [tissue]
Peptide AtlasQ9NS75
HPRD09293
IPIIPI00006914   
Protein Interaction databases
DIP (DOE-UCLA)Q9NS75
IntAct (EBI)Q9NS75
BioGRIDCYSLTR2
STRING (EMBL)CYSLTR2
ZODIACCYSLTR2
Ontologies - Pathways
QuickGOQ9NS75
Ontology : AmiGOcysteinyl leukotriene receptor activity  leukotriene receptor activity  protein binding  cellular_component  plasma membrane  integral component of plasma membrane  immune response  G protein-coupled receptor signaling pathway  neuropeptide signaling pathway  G protein-coupled peptide receptor activity  leukotriene signaling pathway  
Ontology : EGO-EBIcysteinyl leukotriene receptor activity  leukotriene receptor activity  protein binding  cellular_component  plasma membrane  integral component of plasma membrane  immune response  G protein-coupled receptor signaling pathway  neuropeptide signaling pathway  G protein-coupled peptide receptor activity  leukotriene signaling pathway  
Pathways : BIOCARTAEicosanoid Metabolism [Genes]   
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction   
NDEx NetworkCYSLTR2
Atlas of Cancer Signalling NetworkCYSLTR2
Wikipedia pathwaysCYSLTR2
Orthology - Evolution
OrthoDB57105
GeneTree (enSembl)ENSG00000152207
Phylogenetic Trees/Animal Genes : TreeFamCYSLTR2
HOGENOMQ9NS75
Homologs : HomoloGeneCYSLTR2
Homology/Alignments : Family Browser (UCSC)CYSLTR2
Gene fusions - Rearrangements
Fusion Cancer (Beijing)CYSLTR2 [13q14.2]  -  ARMCX4 [Xq22.1]  [FUSC002322]  [FUSC002322]
Fusion : QuiverCYSLTR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYSLTR2 [hg38]
dbVarCYSLTR2
ClinVarCYSLTR2
MonarchCYSLTR2
1000_GenomesCYSLTR2 
Exome Variant ServerCYSLTR2
GNOMAD BrowserENSG00000152207
Varsome BrowserCYSLTR2
Genomic Variants (DGV)CYSLTR2 [DGVbeta]
DECIPHERCYSLTR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYSLTR2 
Mutations
ICGC Data PortalCYSLTR2 
TCGA Data PortalCYSLTR2 
Broad Tumor PortalCYSLTR2
OASIS PortalCYSLTR2 [ Somatic mutations - Copy number]
Cancer Gene: CensusCYSLTR2 
Somatic Mutations in Cancer : COSMICCYSLTR2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCYSLTR2
Mutations and Diseases : HGMDCYSLTR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYSLTR2
DgiDB (Drug Gene Interaction Database)CYSLTR2
DoCM (Curated mutations)CYSLTR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYSLTR2 (select a term)
intoGenCYSLTR2
Cancer3DCYSLTR2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605666   
Orphanet
DisGeNETCYSLTR2
MedgenCYSLTR2
Genetic Testing Registry CYSLTR2
NextProtQ9NS75 [Medical]
GENETestsCYSLTR2
Target ValidationCYSLTR2
Huge Navigator CYSLTR2 [HugePedia]
ClinGenCYSLTR2
Clinical trials, drugs, therapy
MyCancerGenomeCYSLTR2
Protein Interactions : CTD
Pharm GKB GenePA38518
PharosQ9NS75
Clinical trialCYSLTR2
Miscellaneous
canSAR (ICR)CYSLTR2 (select the gene name)
HarmonizomeCYSLTR2
DataMed IndexCYSLTR2
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCYSLTR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:17:45 CET 2021

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