Identity
HGNC
LOCATION
13q14.2
LOCUSID
ALIAS
CYSLT2,CYSLT2R,GPCR21,HG57,HPN321,KPG_011,PSEC0146,hGPCR21
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57105
MIM: 605666
HGNC: 18274
Ensembl: ENSG00000152207
Variants:
dbSNP: 57105
ClinVar: 57105
TCGA: ENSG00000152207
COSMIC: CYSLTR2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38088514 | 2024 | The IL-31/CysLT2R axis is associated with itching in patients with allergic rhinitis. | 0 |
| 38088514 | 2024 | The IL-31/CysLT2R axis is associated with itching in patients with allergic rhinitis. | 0 |
| 36834820 | 2023 | DNA Methylation and Gene Expression of the Cysteinyl Leukotriene Receptors as a Prognostic and Metastatic Factor for Colorectal Cancer Patients. | 1 |
| 36834820 | 2023 | DNA Methylation and Gene Expression of the Cysteinyl Leukotriene Receptors as a Prognostic and Metastatic Factor for Colorectal Cancer Patients. | 1 |
| 35777853 | 2022 | Plasmalogen-Mediated Activation of GPCR21 Regulates Cytolytic Activity of NK Cells against the Target Cells. | 1 |
| 35777853 | 2022 | Plasmalogen-Mediated Activation of GPCR21 Regulates Cytolytic Activity of NK Cells against the Target Cells. | 1 |
| 33288675 | 2021 | Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling. | 17 |
| 33588787 | 2021 | Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma. | 8 |
| 33753496 | 2021 | The CysLT(2)R receptor mediates leukotriene C(4)-driven acute and chronic itch. | 36 |
| 33288675 | 2021 | Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling. | 17 |
| 33588787 | 2021 | Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma. | 8 |
| 33753496 | 2021 | The CysLT(2)R receptor mediates leukotriene C(4)-driven acute and chronic itch. | 36 |
| 31614358 | 2020 | Mutations of GNAQ, GNA11, SF3B1, EIF1AX, PLCB4 and CYSLTR in Uveal Melanoma in Chinese Patients. | 6 |
| 31614358 | 2020 | Mutations of GNAQ, GNA11, SF3B1, EIF1AX, PLCB4 and CYSLTR in Uveal Melanoma in Chinese Patients. | 6 |
| 31126515 | 2019 | Variants in the CYSLTR2 are associated with asthma, atopy markers and helminths infections in the Brazilian population. | 3 |
Citation
Dessen P
CYSLTR2 (cysteinyl leukotriene receptor 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-09-01
Online version: http://atlasgeneticsoncology.org/gene/52856/cysltr2
