Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CYSLTR2 (cysteinyl leukotriene receptor 2)

Identity

Alias_symbol (synonym)CysLT(2)
CYSLT2R
Other aliasCYSLT2
GPCR21
HG57
HPN321
KPG_011
PSEC0146
hGPCR21
HGNC (Hugo) CYSLTR2
LocusID (NCBI) 57105
Atlas_Id 52856
Location 13q14.2  [Link to chromosome band 13q14]
Location_base_pair Starts at 48653711 and ends at 48711225 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CYSLTR2 (13q14.2) / ARMCX4 (Xq22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYSLTR2   18274
Cards
Entrez_Gene (NCBI)CYSLTR2  57105  cysteinyl leukotriene receptor 2
AliasesCYSLT2; CYSLT2R; GPCR21; HG57; 
HPN321; KPG_011; PSEC0146; hGPCR21
GeneCards (Weizmann)CYSLTR2
Ensembl hg19 (Hinxton)ENSG00000152207 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000152207 [Gene_View]  chr13:48653711-48711225 [Contig_View]  CYSLTR2 [Vega]
ICGC DataPortalENSG00000152207
TCGA cBioPortalCYSLTR2
AceView (NCBI)CYSLTR2
Genatlas (Paris)CYSLTR2
WikiGenes57105
SOURCE (Princeton)CYSLTR2
Genetics Home Reference (NIH)CYSLTR2
Genomic and cartography
GoldenPath hg38 (UCSC)CYSLTR2  -     chr13:48653711-48711225 +  13q14.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYSLTR2  -     13q14.2   [Description]    (hg19-Feb_2009)
EnsemblCYSLTR2 - 13q14.2 [CytoView hg19]  CYSLTR2 - 13q14.2 [CytoView hg38]
Mapping of homologs : NCBICYSLTR2 [Mapview hg19]  CYSLTR2 [Mapview hg38]
OMIM605666   
Gene and transcription
Genbank (Entrez)AB038269 AB041947 AK291739 AY853711 BC069160
RefSeq transcript (Entrez)NM_001308465 NM_001308467 NM_001308468 NM_001308469 NM_001308470 NM_001308471 NM_001308476 NM_020377
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYSLTR2
Cluster EST : UnigeneHs.614318 [ NCBI ]
CGAP (NCI)Hs.614318
Alternative Splicing GalleryENSG00000152207
Gene ExpressionCYSLTR2 [ NCBI-GEO ]   CYSLTR2 [ EBI - ARRAY_EXPRESS ]   CYSLTR2 [ SEEK ]   CYSLTR2 [ MEM ]
Gene Expression Viewer (FireBrowse)CYSLTR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57105
GTEX Portal (Tissue expression)CYSLTR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS75   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS75  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS75
Splice isoforms : SwissVarQ9NS75
PhosPhoSitePlusQ9NS75
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)CLT2_recept    Cyst_leuk_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)CYSLTR2
DMDM Disease mutations57105
Blocks (Seattle)CYSLTR2
SuperfamilyQ9NS75
Human Protein AtlasENSG00000152207
Peptide AtlasQ9NS75
HPRD09293
IPIIPI00006914   
Protein Interaction databases
DIP (DOE-UCLA)Q9NS75
IntAct (EBI)Q9NS75
FunCoupENSG00000152207
BioGRIDCYSLTR2
STRING (EMBL)CYSLTR2
ZODIACCYSLTR2
Ontologies - Pathways
QuickGOQ9NS75
Ontology : AmiGOcysteinyl leukotriene receptor activity  leukotriene receptor activity  protein binding  cellular_component  plasma membrane  integral component of plasma membrane  immune response  phospholipase C-activating G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  G-protein coupled peptide receptor activity  positive regulation of cell death  positive regulation of angiogenesis  leukotriene signaling pathway  positive regulation of ERK1 and ERK2 cascade  
Ontology : EGO-EBIcysteinyl leukotriene receptor activity  leukotriene receptor activity  protein binding  cellular_component  plasma membrane  integral component of plasma membrane  immune response  phospholipase C-activating G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  G-protein coupled peptide receptor activity  positive regulation of cell death  positive regulation of angiogenesis  leukotriene signaling pathway  positive regulation of ERK1 and ERK2 cascade  
Pathways : BIOCARTAEicosanoid Metabolism [Genes]   
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction   
NDEx NetworkCYSLTR2
Atlas of Cancer Signalling NetworkCYSLTR2
Wikipedia pathwaysCYSLTR2
Orthology - Evolution
OrthoDB57105
GeneTree (enSembl)ENSG00000152207
Phylogenetic Trees/Animal Genes : TreeFamCYSLTR2
HOVERGENQ9NS75
HOGENOMQ9NS75
Homologs : HomoloGeneCYSLTR2
Homology/Alignments : Family Browser (UCSC)CYSLTR2
Gene fusions - Rearrangements
Fusion Cancer (Beijing)CYSLTR2 [13q14.2]  -  ARMCX4 [Xq22.1]  [FUSC002322]  [FUSC002322]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYSLTR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYSLTR2
dbVarCYSLTR2
ClinVarCYSLTR2
1000_GenomesCYSLTR2 
Exome Variant ServerCYSLTR2
ExAC (Exome Aggregation Consortium)CYSLTR2 (select the gene name)
Genetic variants : HAPMAP57105
Genomic Variants (DGV)CYSLTR2 [DGVbeta]
DECIPHERCYSLTR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYSLTR2 
Mutations
ICGC Data PortalCYSLTR2 
TCGA Data PortalCYSLTR2 
Broad Tumor PortalCYSLTR2
OASIS PortalCYSLTR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYSLTR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYSLTR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYSLTR2
DgiDB (Drug Gene Interaction Database)CYSLTR2
DoCM (Curated mutations)CYSLTR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYSLTR2 (select a term)
intoGenCYSLTR2
Cancer3DCYSLTR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605666   
Orphanet
MedgenCYSLTR2
Genetic Testing Registry CYSLTR2
NextProtQ9NS75 [Medical]
TSGene57105
GENETestsCYSLTR2
Target ValidationCYSLTR2
Huge Navigator CYSLTR2 [HugePedia]
snp3D : Map Gene to Disease57105
BioCentury BCIQCYSLTR2
ClinGenCYSLTR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57105
Chemical/Pharm GKB GenePA38518
Clinical trialCYSLTR2
Miscellaneous
canSAR (ICR)CYSLTR2 (select the gene name)
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYSLTR2
EVEXCYSLTR2
GoPubMedCYSLTR2
iHOPCYSLTR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Sep 25 19:04:39 CEST 2017

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