Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CYTH2 (cytohesin 2)

Identity

Alias (NCBI)ARNO
CTS18
CTS18.1
PSCD2
PSCD2L
SEC7L
Sec7p-L
Sec7p-like
cytohesin-2
HGNC (Hugo) CYTH2
HGNC Alias symbCTS18.1
Sec7p-L
ARNO
Sec7p-like
cytohesin-2
HGNC Previous namePSCD2L
 PSCD2
HGNC Previous namepleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2)
 pleckstrin homology, Sec7 and coiled-coil domains 2
LocusID (NCBI) 9266
Atlas_Id 50360
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 48469208 and ends at 48482314 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CYTH2 (19q13.33) / CYTH2 (19q13.33)CYTH2 (19q13.33) / TAF1D (11q21)HLA-B (6p21.33) / CYTH2 (19q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CYTH2   9502
Cards
Entrez_Gene (NCBI)CYTH2    cytohesin 2
AliasesARNO; CTS18; CTS18.1; PSCD2; 
PSCD2L; SEC7L; Sec7p-L; Sec7p-like; cytohesin-2
GeneCards (Weizmann)CYTH2
Ensembl hg19 (Hinxton)ENSG00000105443 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105443 [Gene_View]  ENSG00000105443 [Sequence]  chr19:48469208-48482314 [Contig_View]  CYTH2 [Vega]
ICGC DataPortalENSG00000105443
TCGA cBioPortalCYTH2
AceView (NCBI)CYTH2
Genatlas (Paris)CYTH2
SOURCE (Princeton)CYTH2
Genetics Home Reference (NIH)CYTH2
Genomic and cartography
GoldenPath hg38 (UCSC)CYTH2  -     chr19:48469208-48482314 +  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYTH2  -     19q13.33   [Description]    (hg19-Feb_2009)
GoldenPathCYTH2 - 19q13.33 [CytoView hg19]  CYTH2 - 19q13.33 [CytoView hg38]
ImmunoBaseENSG00000105443
Genome Data Viewer NCBICYTH2 [Mapview hg19]  
OMIM602488   
Gene and transcription
Genbank (Entrez)AB209573 AF318380 AK091443 AK292405 AK299590
RefSeq transcript (Entrez)NM_004228 NM_017457
Consensus coding sequences : CCDS (NCBI)CYTH2
Gene ExpressionCYTH2 [ NCBI-GEO ]   CYTH2 [ EBI - ARRAY_EXPRESS ]   CYTH2 [ SEEK ]   CYTH2 [ MEM ]
Gene Expression Viewer (FireBrowse)CYTH2 [ Firebrowse - Broad ]
GenevisibleExpression of CYTH2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9266
GTEX Portal (Tissue expression)CYTH2
Human Protein AtlasENSG00000105443-CYTH2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99418   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99418  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99418
PhosPhoSitePlusQ99418
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    SEC7 (PS50190)   
Domains : Interpro (EBI)PH-like_dom_sf    PH_domain    Sec7_C_sf    Sec7_dom    Sec7_dom_sf   
Domain families : Pfam (Sanger)PH (PF00169)    Sec7 (PF01369)   
Domain families : Pfam (NCBI)pfam00169    pfam01369   
Domain families : Smart (EMBL)PH (SM00233)  Sec7 (SM00222)  
Conserved Domain (NCBI)CYTH2
PDB (RSDB)1PBV    1R8M    1R8Q    1R8S    1S9D    4JMI    4JMO    4JWL    4JXH    4L5M    4Z21   
PDB Europe1PBV    1R8M    1R8Q    1R8S    1S9D    4JMI    4JMO    4JWL    4JXH    4L5M    4Z21   
PDB (PDBSum)1PBV    1R8M    1R8Q    1R8S    1S9D    4JMI    4JMO    4JWL    4JXH    4L5M    4Z21   
PDB (IMB)1PBV    1R8M    1R8Q    1R8S    1S9D    4JMI    4JMO    4JWL    4JXH    4L5M    4Z21   
Structural Biology KnowledgeBase1PBV    1R8M    1R8Q    1R8S    1S9D    4JMI    4JMO    4JWL    4JXH    4L5M    4Z21   
SCOP (Structural Classification of Proteins)1PBV    1R8M    1R8Q    1R8S    1S9D    4JMI    4JMO    4JWL    4JXH    4L5M    4Z21   
CATH (Classification of proteins structures)1PBV    1R8M    1R8Q    1R8S    1S9D    4JMI    4JMO    4JWL    4JXH    4L5M    4Z21   
SuperfamilyQ99418
AlphaFold pdb e-kbQ99418   
Human Protein Atlas [tissue]ENSG00000105443-CYTH2 [tissue]
HPRD03925
Protein Interaction databases
DIP (DOE-UCLA)Q99418
IntAct (EBI)Q99418
BioGRIDCYTH2
STRING (EMBL)CYTH2
ZODIACCYTH2
Ontologies - Pathways
QuickGOQ99418
Ontology : AmiGOGolgi membrane  guanyl-nucleotide exchange factor activity  protein binding  cytoplasm  cytosol  plasma membrane  adherens junction  bicellular tight junction  endocytosis  lipid binding  membrane  actin cytoskeleton organization  growth cone  regulation of ARF protein signal transduction  regulation of catalytic activity  inositol 1,4,5 trisphosphate binding  
Ontology : EGO-EBIGolgi membrane  guanyl-nucleotide exchange factor activity  protein binding  cytoplasm  cytosol  plasma membrane  adherens junction  bicellular tight junction  endocytosis  lipid binding  membrane  actin cytoskeleton organization  growth cone  regulation of ARF protein signal transduction  regulation of catalytic activity  inositol 1,4,5 trisphosphate binding  
Pathways : BIOCARTAADP-Ribosylation Factor [Genes]   
NDEx NetworkCYTH2
Atlas of Cancer Signalling NetworkCYTH2
Wikipedia pathwaysCYTH2
Orthology - Evolution
OrthoDB9266
GeneTree (enSembl)ENSG00000105443
Phylogenetic Trees/Animal Genes : TreeFamCYTH2
Homologs : HomoloGeneCYTH2
Homology/Alignments : Family Browser (UCSC)CYTH2
Gene fusions - Rearrangements
Fusion : QuiverCYTH2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYTH2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYTH2
dbVarCYTH2
ClinVarCYTH2
MonarchCYTH2
1000_GenomesCYTH2 
Exome Variant ServerCYTH2
GNOMAD BrowserENSG00000105443
Varsome BrowserCYTH2
ACMGCYTH2 variants
VarityQ99418
Genomic Variants (DGV)CYTH2 [DGVbeta]
DECIPHERCYTH2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYTH2 
Mutations
ICGC Data PortalCYTH2 
TCGA Data PortalCYTH2 
Broad Tumor PortalCYTH2
OASIS PortalCYTH2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYTH2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCYTH2
Mutations and Diseases : HGMDCYTH2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCYTH2
DgiDB (Drug Gene Interaction Database)CYTH2
DoCM (Curated mutations)CYTH2
CIViC (Clinical Interpretations of Variants in Cancer)CYTH2
Cancer3DCYTH2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602488   
Orphanet
DisGeNETCYTH2
MedgenCYTH2
Genetic Testing Registry CYTH2
NextProtQ99418 [Medical]
GENETestsCYTH2
Target ValidationCYTH2
Huge Navigator CYTH2 [HugePedia]
ClinGenCYTH2
Clinical trials, drugs, therapy
MyCancerGenomeCYTH2
Protein Interactions : CTDCYTH2
Pharm GKB GenePA33849
PharosQ99418
Clinical trialCYTH2
Miscellaneous
canSAR (ICR)CYTH2
HarmonizomeCYTH2
DataMed IndexCYTH2
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCYTH2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:06:01 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.