Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CYTH4 (cytohesin 4)

Identity

Alias_namesPSCD4
pleckstrin homology, Sec7 and coiled/coil domains 4
pleckstrin homology, Sec7 and coiled-coil domains 4
Alias_symbol (synonym)CYT4
cytohesin-4
Other aliasDJ63G5.1
HGNC (Hugo) CYTH4
LocusID (NCBI) 27128
Atlas_Id 43435
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 37282383 and ends at 37315348 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CYTH4   9505
Cards
Entrez_Gene (NCBI)CYTH4  27128  cytohesin 4
AliasesCYT4; DJ63G5.1; PSCD4; cytohesin-4
GeneCards (Weizmann)CYTH4
Ensembl hg19 (Hinxton)ENSG00000100055 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100055 [Gene_View]  ENSG00000100055 [Sequence]  chr22:37282383-37315348 [Contig_View]  CYTH4 [Vega]
ICGC DataPortalENSG00000100055
TCGA cBioPortalCYTH4
AceView (NCBI)CYTH4
Genatlas (Paris)CYTH4
WikiGenes27128
SOURCE (Princeton)CYTH4
Genetics Home Reference (NIH)CYTH4
Genomic and cartography
GoldenPath hg38 (UCSC)CYTH4  -     chr22:37282383-37315348 +  22q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYTH4  -     22q13.1   [Description]    (hg19-Feb_2009)
EnsemblCYTH4 - 22q13.1 [CytoView hg19]  CYTH4 - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBICYTH4 [Mapview hg19]  CYTH4 [Mapview hg38]
OMIM606514   
Gene and transcription
Genbank (Entrez)AF075458 AF125349 AK002145 AK024428 AK304453
RefSeq transcript (Entrez)NM_001318024 NM_013385
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYTH4
Cluster EST : UnigeneHs.170944 [ NCBI ]
CGAP (NCI)Hs.170944
Alternative Splicing GalleryENSG00000100055
Gene ExpressionCYTH4 [ NCBI-GEO ]   CYTH4 [ EBI - ARRAY_EXPRESS ]   CYTH4 [ SEEK ]   CYTH4 [ MEM ]
Gene Expression Viewer (FireBrowse)CYTH4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27128
GTEX Portal (Tissue expression)CYTH4
Human Protein AtlasENSG00000100055-CYTH4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UIA0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UIA0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UIA0
Splice isoforms : SwissVarQ9UIA0
PhosPhoSitePlusQ9UIA0
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    SEC7 (PS50190)   
Domains : Interpro (EBI)PH-like_dom_sf    PH_domain    Sec7_C_sf    Sec7_dom    Sec7_dom_sf   
Domain families : Pfam (Sanger)PH (PF00169)    Sec7 (PF01369)   
Domain families : Pfam (NCBI)pfam00169    pfam01369   
Domain families : Smart (EMBL)PH (SM00233)  Sec7 (SM00222)  
Conserved Domain (NCBI)CYTH4
DMDM Disease mutations27128
Blocks (Seattle)CYTH4
SuperfamilyQ9UIA0
Human Protein Atlas [tissue]ENSG00000100055-CYTH4 [tissue]
Peptide AtlasQ9UIA0
HPRD07354
IPIIPI00395879   IPI01018298   IPI00879140   IPI00878487   IPI00877882   IPI00877991   IPI00878224   IPI00878845   IPI00879378   
Protein Interaction databases
DIP (DOE-UCLA)Q9UIA0
IntAct (EBI)Q9UIA0
FunCoupENSG00000100055
BioGRIDCYTH4
STRING (EMBL)CYTH4
ZODIACCYTH4
Ontologies - Pathways
QuickGOQ9UIA0
Ontology : AmiGOGolgi membrane  ARF guanyl-nucleotide exchange factor activity  cytosol  plasma membrane  lipid binding  regulation of ARF protein signal transduction  
Ontology : EGO-EBIGolgi membrane  ARF guanyl-nucleotide exchange factor activity  cytosol  plasma membrane  lipid binding  regulation of ARF protein signal transduction  
NDEx NetworkCYTH4
Atlas of Cancer Signalling NetworkCYTH4
Wikipedia pathwaysCYTH4
Orthology - Evolution
OrthoDB27128
GeneTree (enSembl)ENSG00000100055
Phylogenetic Trees/Animal Genes : TreeFamCYTH4
HOVERGENQ9UIA0
HOGENOMQ9UIA0
Homologs : HomoloGeneCYTH4
Homology/Alignments : Family Browser (UCSC)CYTH4
Gene fusions - Rearrangements
Fusion : QuiverCYTH4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYTH4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYTH4
dbVarCYTH4
ClinVarCYTH4
1000_GenomesCYTH4 
Exome Variant ServerCYTH4
ExAC (Exome Aggregation Consortium)ENSG00000100055
GNOMAD BrowserENSG00000100055
Varsome BrowserCYTH4
Genetic variants : HAPMAP27128
Genomic Variants (DGV)CYTH4 [DGVbeta]
DECIPHERCYTH4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYTH4 
Mutations
ICGC Data PortalCYTH4 
TCGA Data PortalCYTH4 
Broad Tumor PortalCYTH4
OASIS PortalCYTH4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYTH4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYTH4
intOGen PortalCYTH4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CYTH4
DgiDB (Drug Gene Interaction Database)CYTH4
DoCM (Curated mutations)CYTH4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYTH4 (select a term)
intoGenCYTH4
Cancer3DCYTH4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606514   
Orphanet
DisGeNETCYTH4
MedgenCYTH4
Genetic Testing Registry CYTH4
NextProtQ9UIA0 [Medical]
TSGene27128
GENETestsCYTH4
Target ValidationCYTH4
Huge Navigator CYTH4 [HugePedia]
snp3D : Map Gene to Disease27128
BioCentury BCIQCYTH4
ClinGenCYTH4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27128
Chemical/Pharm GKB GenePA164718621
Clinical trialCYTH4
Miscellaneous
canSAR (ICR)CYTH4 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYTH4
EVEXCYTH4
GoPubMedCYTH4
iHOPCYTH4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:18:19 CEST 2018
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