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DAAM2 (dishevelled associated activator of morphogenesis 2)

Identity

Alias_symbol (synonym)KIAA0381
Other aliasdJ90A20A.1
HGNC (Hugo) DAAM2
LocusID (NCBI) 23500
Atlas_Id 62279
Location 6p21.2  [Link to chromosome band 6p21]
Location_base_pair Starts at 39792383 and ends at 39904877 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DAAM2 (6p21.2) / CCDC80 (3q13.2)LRRC1 (6p12.1) / DAAM2 (6p21.2)USP49 (6p21.1) / DAAM2 (6p21.2)
LRRC1 DAAM2USP49 DAAM2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  t(6;6)(p12;p21) LRRC1/DAAM2
t(6;6)(p21;p21) USP49/DAAM2


External links

Nomenclature
HGNC (Hugo)DAAM2   18143
Cards
Entrez_Gene (NCBI)DAAM2  23500  dishevelled associated activator of morphogenesis 2
AliasesdJ90A20A.1
GeneCards (Weizmann)DAAM2
Ensembl hg19 (Hinxton)ENSG00000146122 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000146122 [Gene_View]  ENSG00000146122 [Sequence]  chr6:39792383-39904877 [Contig_View]  DAAM2 [Vega]
ICGC DataPortalENSG00000146122
TCGA cBioPortalDAAM2
AceView (NCBI)DAAM2
Genatlas (Paris)DAAM2
WikiGenes23500
SOURCE (Princeton)DAAM2
Genetics Home Reference (NIH)DAAM2
Genomic and cartography
GoldenPath hg38 (UCSC)DAAM2  -     chr6:39792383-39904877 +  6p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DAAM2  -     6p21.2   [Description]    (hg19-Feb_2009)
EnsemblDAAM2 - 6p21.2 [CytoView hg19]  DAAM2 - 6p21.2 [CytoView hg38]
Mapping of homologs : NCBIDAAM2 [Mapview hg19]  DAAM2 [Mapview hg38]
OMIM606627   
Gene and transcription
Genbank (Entrez)AB002379 AK127022 AK310941 AL596701 AL833083
RefSeq transcript (Entrez)NM_001201427 NM_015345
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DAAM2
Cluster EST : UnigeneHs.734949 [ NCBI ]
CGAP (NCI)Hs.734949
Alternative Splicing GalleryENSG00000146122
Gene ExpressionDAAM2 [ NCBI-GEO ]   DAAM2 [ EBI - ARRAY_EXPRESS ]   DAAM2 [ SEEK ]   DAAM2 [ MEM ]
Gene Expression Viewer (FireBrowse)DAAM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23500
GTEX Portal (Tissue expression)DAAM2
Human Protein AtlasENSG00000146122-DAAM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86T65   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86T65  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86T65
Splice isoforms : SwissVarQ86T65
PhosPhoSitePlusQ86T65
Domaine pattern : Prosite (Expaxy)DAD (PS51231)    FH2 (PS51444)    GBD_FH3 (PS51232)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    DAD_dom    FH2_Formin    FH3_dom    GBD/FH3_dom    GTPase-bd   
Domain families : Pfam (Sanger)Drf_FH3 (PF06367)    Drf_GBD (PF06371)    FH2 (PF02181)   
Domain families : Pfam (NCBI)pfam06367    pfam06371    pfam02181   
Domain families : Smart (EMBL)Drf_FH3 (SM01139)  Drf_GBD (SM01140)  FH2 (SM00498)  
Conserved Domain (NCBI)DAAM2
DMDM Disease mutations23500
Blocks (Seattle)DAAM2
SuperfamilyQ86T65
Human Protein Atlas [tissue]ENSG00000146122-DAAM2 [tissue]
Peptide AtlasQ86T65
HPRD09434
IPIIPI00514893   IPI00456691   IPI00982606   
Protein Interaction databases
DIP (DOE-UCLA)Q86T65
IntAct (EBI)Q86T65
FunCoupENSG00000146122
BioGRIDDAAM2
STRING (EMBL)DAAM2
ZODIACDAAM2
Ontologies - Pathways
QuickGOQ86T65
Ontology : AmiGOactin binding  determination of left/right symmetry  Rho GTPase binding  actin cytoskeleton organization  extracellular exosome  
Ontology : EGO-EBIactin binding  determination of left/right symmetry  Rho GTPase binding  actin cytoskeleton organization  extracellular exosome  
Pathways : KEGGWnt signaling pathway   
NDEx NetworkDAAM2
Atlas of Cancer Signalling NetworkDAAM2
Wikipedia pathwaysDAAM2
Orthology - Evolution
OrthoDB23500
GeneTree (enSembl)ENSG00000146122
Phylogenetic Trees/Animal Genes : TreeFamDAAM2
HOVERGENQ86T65
HOGENOMQ86T65
Homologs : HomoloGeneDAAM2
Homology/Alignments : Family Browser (UCSC)DAAM2
Gene fusions - Rearrangements
Fusion PortalLRRC1 DAAM2
Fusion PortalUSP49 DAAM2
Fusion : QuiverDAAM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDAAM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DAAM2
dbVarDAAM2
ClinVarDAAM2
1000_GenomesDAAM2 
Exome Variant ServerDAAM2
ExAC (Exome Aggregation Consortium)ENSG00000146122
GNOMAD BrowserENSG00000146122
Varsome BrowserDAAM2
Genetic variants : HAPMAP23500
Genomic Variants (DGV)DAAM2 [DGVbeta]
DECIPHERDAAM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDAAM2 
Mutations
ICGC Data PortalDAAM2 
TCGA Data PortalDAAM2 
Broad Tumor PortalDAAM2
OASIS PortalDAAM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDAAM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDAAM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DAAM2
DgiDB (Drug Gene Interaction Database)DAAM2
DoCM (Curated mutations)DAAM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DAAM2 (select a term)
intoGenDAAM2
Cancer3DDAAM2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606627   
Orphanet
DisGeNETDAAM2
MedgenDAAM2
Genetic Testing Registry DAAM2
NextProtQ86T65 [Medical]
TSGene23500
GENETestsDAAM2
Target ValidationDAAM2
Huge Navigator DAAM2 [HugePedia]
snp3D : Map Gene to Disease23500
BioCentury BCIQDAAM2
ClinGenDAAM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23500
Chemical/Pharm GKB GenePA27130
Clinical trialDAAM2
Miscellaneous
canSAR (ICR)DAAM2 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDAAM2
EVEXDAAM2
GoPubMedDAAM2
iHOPDAAM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:42:04 CEST 2018

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