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DACT3 (dishevelled binding antagonist of beta catenin 3)

Identity

Alias_namesRRR1
arginine rich region 1
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
Alias_symbol (synonym)MGC15476
DAPPER3
Other alias
HGNC (Hugo) DACT3
LocusID (NCBI) 147906
Atlas_Id 50253
Location 19q13.32  [Link to chromosome band 19q13]
Location_base_pair Starts at 46647564 and ends at 46654657 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DACT3   30745
Cards
Entrez_Gene (NCBI)DACT3  147906  dishevelled binding antagonist of beta catenin 3
AliasesDAPPER3; RRR1
GeneCards (Weizmann)DACT3
Ensembl hg19 (Hinxton)ENSG00000197380 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197380 [Gene_View]  chr19:46647564-46654657 [Contig_View]  DACT3 [Vega]
ICGC DataPortalENSG00000197380
TCGA cBioPortalDACT3
AceView (NCBI)DACT3
Genatlas (Paris)DACT3
WikiGenes147906
SOURCE (Princeton)DACT3
Genetics Home Reference (NIH)DACT3
Genomic and cartography
GoldenPath hg38 (UCSC)DACT3  -     chr19:46647564-46654657 -  19q13.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DACT3  -     19q13.32   [Description]    (hg19-Feb_2009)
EnsemblDACT3 - 19q13.32 [CytoView hg19]  DACT3 - 19q13.32 [CytoView hg38]
Mapping of homologs : NCBIDACT3 [Mapview hg19]  DACT3 [Mapview hg38]
OMIM611112   
Gene and transcription
Genbank (Entrez)AI769079 BC016161 BC034052 BE274342 BF515069
RefSeq transcript (Entrez)NM_001301046 NM_145056
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DACT3
Cluster EST : UnigeneHs.515490 [ NCBI ]
CGAP (NCI)Hs.515490
Alternative Splicing GalleryENSG00000197380
Gene ExpressionDACT3 [ NCBI-GEO ]   DACT3 [ EBI - ARRAY_EXPRESS ]   DACT3 [ SEEK ]   DACT3 [ MEM ]
Gene Expression Viewer (FireBrowse)DACT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)147906
GTEX Portal (Tissue expression)DACT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96B18   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96B18  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96B18
Splice isoforms : SwissVarQ96B18
PhosPhoSitePlusQ96B18
Domains : Interpro (EBI)Dact3    Dapper   
Domain families : Pfam (Sanger)Dapper (PF15268)   
Domain families : Pfam (NCBI)pfam15268   
Conserved Domain (NCBI)DACT3
DMDM Disease mutations147906
Blocks (Seattle)DACT3
SuperfamilyQ96B18
Human Protein AtlasENSG00000197380
Peptide AtlasQ96B18
HPRD17505
IPIIPI00059662   IPI00166706   IPI00873974   
Protein Interaction databases
DIP (DOE-UCLA)Q96B18
IntAct (EBI)Q96B18
FunCoupENSG00000197380
BioGRIDDACT3
STRING (EMBL)DACT3
ZODIACDACT3
Ontologies - Pathways
QuickGOQ96B18
Ontology : AmiGOprotein kinase C binding  protein kinase C binding  cytoplasm  beta-catenin binding  negative regulation of epithelial to mesenchymal transition  Wnt signaling pathway  negative regulation of Wnt signaling pathway  negative regulation of cell growth  negative regulation of catenin import into nucleus  identical protein binding  protein kinase A binding  protein kinase A binding  delta-catenin binding  delta-catenin binding  negative regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIprotein kinase C binding  protein kinase C binding  cytoplasm  beta-catenin binding  negative regulation of epithelial to mesenchymal transition  Wnt signaling pathway  negative regulation of Wnt signaling pathway  negative regulation of cell growth  negative regulation of catenin import into nucleus  identical protein binding  protein kinase A binding  protein kinase A binding  delta-catenin binding  delta-catenin binding  negative regulation of canonical Wnt signaling pathway  
NDEx NetworkDACT3
Atlas of Cancer Signalling NetworkDACT3
Wikipedia pathwaysDACT3
Orthology - Evolution
OrthoDB147906
GeneTree (enSembl)ENSG00000197380
Phylogenetic Trees/Animal Genes : TreeFamDACT3
HOVERGENQ96B18
HOGENOMQ96B18
Homologs : HomoloGeneDACT3
Homology/Alignments : Family Browser (UCSC)DACT3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDACT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DACT3
dbVarDACT3
ClinVarDACT3
1000_GenomesDACT3 
Exome Variant ServerDACT3
ExAC (Exome Aggregation Consortium)DACT3 (select the gene name)
Genetic variants : HAPMAP147906
Genomic Variants (DGV)DACT3 [DGVbeta]
DECIPHERDACT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDACT3 
Mutations
ICGC Data PortalDACT3 
TCGA Data PortalDACT3 
Broad Tumor PortalDACT3
OASIS PortalDACT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDACT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDACT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DACT3
DgiDB (Drug Gene Interaction Database)DACT3
DoCM (Curated mutations)DACT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DACT3 (select a term)
intoGenDACT3
Cancer3DDACT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611112   
Orphanet
MedgenDACT3
Genetic Testing Registry DACT3
NextProtQ96B18 [Medical]
TSGene147906
GENETestsDACT3
Target ValidationDACT3
Huge Navigator DACT3 [HugePedia]
snp3D : Map Gene to Disease147906
BioCentury BCIQDACT3
ClinGenDACT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD147906
Chemical/Pharm GKB GenePA162383145
Clinical trialDACT3
Miscellaneous
canSAR (ICR)DACT3 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDACT3
EVEXDACT3
GoPubMedDACT3
iHOPDACT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:51:15 CEST 2017

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