Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DAGLA (diacylglycerol lipase alpha)

Identity

Alias_namesC11orf11
chromosome 11 open reading frame 11
diacylglycerol lipase, alpha
Alias_symbol (synonym)KIAA0659
NSDDR
DAGLALPHA
Other aliasDAGL(ALPHA)
HGNC (Hugo) DAGLA
LocusID (NCBI) 747
Atlas_Id 56014
Location 11q12.2  [Link to chromosome band 11q12]
Location_base_pair Starts at 61680433 and ends at 61747002 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DAGLA (11q12.2) / DAGLA (11q12.2)DAGLA (11q12.2) / PPP1R32 (11q12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DAGLA   1165
Cards
Entrez_Gene (NCBI)DAGLA  747  diacylglycerol lipase alpha
AliasesC11orf11; DAGL(ALPHA); DAGLALPHA; NSDDR
GeneCards (Weizmann)DAGLA
Ensembl hg19 (Hinxton)ENSG00000134780 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134780 [Gene_View]  chr11:61680433-61747002 [Contig_View]  DAGLA [Vega]
ICGC DataPortalENSG00000134780
TCGA cBioPortalDAGLA
AceView (NCBI)DAGLA
Genatlas (Paris)DAGLA
WikiGenes747
SOURCE (Princeton)DAGLA
Genetics Home Reference (NIH)DAGLA
Genomic and cartography
GoldenPath hg38 (UCSC)DAGLA  -     chr11:61680433-61747002 +  11q12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DAGLA  -     11q12.2   [Description]    (hg19-Feb_2009)
EnsemblDAGLA - 11q12.2 [CytoView hg19]  DAGLA - 11q12.2 [CytoView hg38]
Mapping of homologs : NCBIDAGLA [Mapview hg19]  DAGLA [Mapview hg38]
OMIM614015   
Gene and transcription
Genbank (Entrez)AB014559 AI702626 AY275377 BC150176 BC150195
RefSeq transcript (Entrez)NM_006133
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DAGLA
Cluster EST : UnigeneHs.241564 [ NCBI ]
CGAP (NCI)Hs.241564
Alternative Splicing GalleryENSG00000134780
Gene ExpressionDAGLA [ NCBI-GEO ]   DAGLA [ EBI - ARRAY_EXPRESS ]   DAGLA [ SEEK ]   DAGLA [ MEM ]
Gene Expression Viewer (FireBrowse)DAGLA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)747
GTEX Portal (Tissue expression)DAGLA
Human Protein AtlasENSG00000134780-DAGLA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4D2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4D2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4D2
Splice isoforms : SwissVarQ9Y4D2
Catalytic activity : Enzyme3.1.1.- [ Enzyme-Expasy ]   3.1.1.-3.1.1.- [ IntEnz-EBI ]   3.1.1.- [ BRENDA ]   3.1.1.- [ KEGG ]   
PhosPhoSitePlusQ9Y4D2
Domaine pattern : Prosite (Expaxy)LIPASE_SER (PS00120)   
Domains : Interpro (EBI)AB_hydrolase    Fungal_lipase-like   
Domain families : Pfam (Sanger)Lipase_3 (PF01764)   
Domain families : Pfam (NCBI)pfam01764   
Conserved Domain (NCBI)DAGLA
DMDM Disease mutations747
Blocks (Seattle)DAGLA
SuperfamilyQ9Y4D2
Human Protein Atlas [tissue]ENSG00000134780-DAGLA [tissue]
Peptide AtlasQ9Y4D2
HPRD07092
IPIIPI00000706   IPI01011277   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4D2
IntAct (EBI)Q9Y4D2
FunCoupENSG00000134780
BioGRIDDAGLA
STRING (EMBL)DAGLA
ZODIACDAGLA
Ontologies - Pathways
QuickGOQ9Y4D2
Ontology : AmiGOplasma membrane  G-protein coupled glutamate receptor signaling pathway  neuroblast proliferation  integral component of membrane  arachidonic acid metabolic process  neurotransmitter biosynthetic process  varicosity  postsynaptic membrane  diacylglycerol catabolic process  metal ion binding  acylglycerol lipase activity  endocannabinoid signaling pathway  retrograde trans-synaptic signaling by endocannabinoid  
Ontology : EGO-EBIplasma membrane  G-protein coupled glutamate receptor signaling pathway  neuroblast proliferation  integral component of membrane  arachidonic acid metabolic process  neurotransmitter biosynthetic process  varicosity  postsynaptic membrane  diacylglycerol catabolic process  metal ion binding  acylglycerol lipase activity  endocannabinoid signaling pathway  retrograde trans-synaptic signaling by endocannabinoid  
Pathways : KEGGRetrograde endocannabinoid signaling   
NDEx NetworkDAGLA
Atlas of Cancer Signalling NetworkDAGLA
Wikipedia pathwaysDAGLA
Orthology - Evolution
OrthoDB747
GeneTree (enSembl)ENSG00000134780
Phylogenetic Trees/Animal Genes : TreeFamDAGLA
HOVERGENQ9Y4D2
HOGENOMQ9Y4D2
Homologs : HomoloGeneDAGLA
Homology/Alignments : Family Browser (UCSC)DAGLA
Gene fusions - Rearrangements
Tumor Fusion PortalDAGLA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDAGLA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DAGLA
dbVarDAGLA
ClinVarDAGLA
1000_GenomesDAGLA 
Exome Variant ServerDAGLA
ExAC (Exome Aggregation Consortium)ENSG00000134780
GNOMAD BrowserENSG00000134780
Genetic variants : HAPMAP747
Genomic Variants (DGV)DAGLA [DGVbeta]
DECIPHERDAGLA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDAGLA 
Mutations
ICGC Data PortalDAGLA 
TCGA Data PortalDAGLA 
Broad Tumor PortalDAGLA
OASIS PortalDAGLA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDAGLA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDAGLA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DAGLA
DgiDB (Drug Gene Interaction Database)DAGLA
DoCM (Curated mutations)DAGLA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DAGLA (select a term)
intoGenDAGLA
Cancer3DDAGLA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614015   
Orphanet
DisGeNETDAGLA
MedgenDAGLA
Genetic Testing Registry DAGLA
NextProtQ9Y4D2 [Medical]
TSGene747
GENETestsDAGLA
Target ValidationDAGLA
Huge Navigator DAGLA [HugePedia]
snp3D : Map Gene to Disease747
BioCentury BCIQDAGLA
ClinGenDAGLA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD747
Chemical/Pharm GKB GenePA162383158
Clinical trialDAGLA
Miscellaneous
canSAR (ICR)DAGLA (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDAGLA
EVEXDAGLA
GoPubMedDAGLA
iHOPDAGLA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:09:56 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.